Testing a Swallowable Heat-Sensing Capsule in Crohn's Disease and Healthy Adults
Tests a swallowable heat-sensing capsule in adults with Crohn's or healthy adults.
Key facts
- Who runs it
- Massachusetts General Hospital
- Where
- Boston, United StatesSee the site
- Trial code
- Registry title
- Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance
- Status
- Recruiting
- People taking part
- 25 people, planned
- Started
- 3 Jun 2025
- Expected to end
- 30 Apr 2027
- Type of study
- Interventional
- Treatments tested
- Feasibility to obtain thermal variance measurements using a wireless thermal capsule
- Record updated
- 2 October 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for healthy adults with no known illnesses. They swallow a small wireless capsule that measures temperature in the gut.
- Age
- 18 to 75 years old
- Sex
- All sexes can join
- Earlier treatment
- Cannot have had intestinal surgery in the past. Cannot have joined another drug or device study within 30 days before enrolment.
Main reasons for not taking part
- Trouble swallowing, or a condition that raises the risk of the capsule getting stuck, such as a narrowing or blockage of the gut
- History of inflammatory bowel disease, Crohn's disease, chronic constipation or rectal bleeding
- Kidney disease, congestive heart failure, or Type I or Type II diabetes
- Cardiac pacemaker or other implanted electromedical device, or an MRI planned within 7 days after swallowing the capsule
- Pregnant, suspected pregnant, or breast-feeding
This trial only enrols healthy participants. The registry sentence this rests on: Participant is considered healthy, with no known illnesses
The registry criteria, word for word
Show all 23 criteriaShow less
Who can take part
- Participant is 18 -75 years old
- Participant is considered healthy, with no known illnesses
- Participant can follow fasting requirements
- Participant can follow bowel prep instructions
- Participant can provide informed consent
Who cannot take part
- Participant with chronic usage of nonsteroidal anti-inflammatory drugs (NSAIDs)
- Participant who has had intestinal surgery in the past
- Participant has participated in an investigational drug or device research study within 30 days of enrollment that may interfere with the subject's safety or ability to participate in this study
- Participant with current dysphagia or any swallowing disorder
- Participant with any current condition believed to have an increased risk of capsule retention such as gastrointestinal strictures, intestinal tumors, bowel obstruction, incomplete colonoscopies or fistula
- Participant with a history of inflammatory bowel disease (IBD), intestinal Crohn's disease, chronic constipation, or rectal bleeding
- Participant with a history of congestive heart failure
- Participant with Type I or Type II Diabetes
- Participant has a cardiac pacemaker or other implanted electromedical device
- Participant with clinical evidence of renal disease, including clinically significant laboratory abnormalities of renal function within the past 6 months
- Participant is older than 75 years of age
- Participant with a diagnosis of gastroparesis or small bowel or large bowel dysmotility
- Participants with a known contradiction to metoclopramide
- Participants with a known contraindication to polyethylene glycol
- Participant with currently suspected or diagnosed with hematochezia, melena, iron deficiency with or without anemia
- Participant expected to undergo MRI examination within 7 days after ingestion of the capsule
- Participant with delayed gastric emptying
- Participant who is pregnant, suspected pregnant, or is actively breast-feeding
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Where in United States
- Massachusetts General HospitalBoston, United StatesContact: Anita ChungTaking people
About the trial
What the trial wants to find out
The goal of this research is to learn how a new device called the wireless thermal capsule (WTC) can collect thermal data to help see diseases that happen in the gastrointestinal (GI) tract, such as Crohn's Disease.
The group in the trial
- Healthy VolunteersTreatment being tested
25 healthy adult participants with no pre-existing gastrointestinal disorders will be enrolled at MGH
Treatment: Feasibility to obtain thermal variance measurements using a wireless thermal capsule
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance
- Plain-language title
- Testing a Swallowable Heat-Sensing Capsule in Crohn's Disease and Healthy AdultsGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT07033208, who can take part
- Record updated
- 2 October 2026