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The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study

Key facts

Who runs it
Duke University
Where
Boston, Durham, Miami, and Pittsburgh, United StatesSee the 4 sites
Trial code
Status
Not yet recruiting
People taking part
400 people, planned
Starts
1 Feb 2027
Expected to end
1 Aug 2030
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Community Paramedic Standard of Care (CP SOC)
  • CROSSROADS
Record updated
14 October 2026

Who can take part

Age
18 years and older
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

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Who can take part

  • 18 years old or older
  • Has interacted with a CP team (and, thus, experienced a non-fatal opioid and/or stimulant overdose) in the last 30 days
  • Has independent legal agency
  • Able to independently provide informed consent; and
  • Able to speak and understand English

Who cannot take part

  • Active, severe, and untreated mental illness that would make providing consent impossible

Where in United States

  • Boston Medical CenterBoston, United StatesContact: Alysse Wurcel, MD (principal investigator)Not yet recruiting
  • Duke UniversityDurham, United StatesContact: Margaret Roach, MPHNot yet recruiting
  • University of MiamiMiami, United StatesContact: Kathryn Nowotny, PhD (principal investigator)Not yet recruiting
  • University of PittsburghPittsburgh, United StatesContact: Emily Dauria, PhD (principal investigator)Not yet recruiting

About the trial

What the trial wants to find out

The goal of this clinical trial is to develop and test the CROSSROADS intervention. CROSSROADS is designed for people who have recently survived an opioid and/or stimulant-related non-fatal overdose and had contact with staff from a Community Paramedic (CP) program.

Read full original descriptionShow less

Participants will be randomly placed into one of two groups:

1) Standard of care from the CP program, or 2) CROSSROADS, which includes CP care plus a Medical-Legal Partnership (MLP). The MLP helps people with legal problems that can affect their health-- like issues with housing or public benefits.

Researchers will test if the CROSSROADS intervention reduces drug use and involvement with the criminal legal system.

People in the study will be followed for one year and asked to complete surveys at the beginning, and again at 1 month, 6 months, and 12 months.

The 2 groups in the trial

  • Community Paramedic Standard of Care (CP SOC)Existing treatment, for comparison

    The community paramedic (CP) standard of care (SOC) has three basic components across all study sites. The core components of the CP SOC are that CPs: 1) are deployed via 911 as an opioid and/or stimulant overdose response; 2) provide Medications for Opioid Use Disorder (MOUD), harm reduction service referrals, and link patients to health and social programs as needed; and 3) provide long-term follow-up care in the field after initial contact.

  • CROSSROADSTreatment being tested

    The community paramedic (CP) standard of care (SOC) has three basic components across the sites. The core components of the CP SOC are that CPs: 1) are deployed via 911 as an opioid and/or stimulant overdose response; 2) provide Medications for Opioid Use Disorder (MOUD), harm reduction service referrals, and link patients to health and social programs as needed; and 3) provide long-term follow-up care in the field after initial contact. The CROSSROADS intervention will utilize these SOC aspects and build in technology-supported medical-legal partnerships (MLP) via Docs for Health (D4H) that identifies and addresses health-harming legal needs (HHLN). While CP SOC may refer to services that address some HHLN, the key component of the CROSSROADS intervention is the direct identification and addressing of HHLN via D4H.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services (CROSSROADS) Study
Record updated
14 October 2026