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Taking people in United StatesPhase 2

Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage

Key facts

Who runs it
The University of Texas Medical Branch, Galveston
Where
Galveston, United StatesSee the site
Trial code
Status
Recruiting
Phase
Phase 2
People taking part
15 people, planned
Started
2 Jan 2026
Expected to end
Aug 2027
Type of study
Interventional, 3 groupsOne group gets no study treatment, for comparison.
Treatments tested
  • Lidocaine
  • Lidocaine and Dexamethasone
Record updated
3 November 2026

Who can take part

Age
18 years to 100 years
Sex
Women and men
Healthy volunteers
Cannot take part

The registry criteria, word for word

Show all 11 criteriaShow less

Who can take part

  • Age ≥18 years
  • Diagnosed with aneurysmal SAH, Hunt and Hess Grades 1-2
  • Consent to study procedures and follow-up evaluations

Who cannot take part

  • Previous MMA interventions
  • Previous craniotomies or need for craniotomy
  • Known allergies to lidocaine or steroids
  • Arteriovenous malformations
  • Dural Arteriovenous Fistulas
  • Other significant intracranial pathologies
  • Hemodynamic instability preventing safe intervention
  • Need for external ventricular drain

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 100 years old?

Where in United States

  • University of Texas Medical Branch - GalvestonGalveston, United StatesContact: Matias CostaTaking people

About the trial

What the trial wants to find out

The goal of this clinical trial is to learn if an infusion of lidocaine, with or without steroids, into the middle meningeal artery (MMA) helps relieve severe headaches in patients with spontaneous subarachnoid hemorrhage (SAH). It will also study the safety of this treatment.

The 3 groups in the trial

  • Lidocaine (50 mg bilaterally)Treatment being tested

    The participants will receive 50 mg of lidocaine.

    Treatment: Lidocaine

  • Lidocaine (50 mg) + Dexamethasone (10 mg bilaterally)Treatment being tested

    The participant will receive Lidocaine (50 mg) + Dexamethasone (10 mg bilaterally)

    Treatment: Lidocaine and Dexamethasone

  • No injection (Control group)No study treatment, for comparison

    The participant will not receive an injection.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Endovascular Infusion of Lidocaine and Steroids in the Middle Meningeal Artery for Pain Management in Spontaneous Subarachnoid Hemorrhage Patients
Fit questions
Built from NCT07294118, who can take part
Record updated
3 November 2026