Comparing two food supplements for people with mild high cholesterol
Compares Cynacol with Metacol on cholesterol levels in people with mild hypercholesterolemia.
Plain-language title generated from the registry record
Registry title: Effect of Two Food Supplements on Lipid Profile in Patients With Mild Hypercholesterolemia
Key facts
- Where
- Pavia, ItalySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 35 and 70 years old?
Source: NCT07295327, who can take part
Where in Italy
- Fondazione IRCCS Policlinico San MatteoPavia, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Fondazione IRCCS Policlinico San Matteo di Pavia
- Trial code
- NCT07295327
- Record updated
- 19 December 2025
- Original description
The primary outcome is to evaluate the effect of Cynacol on the change in LDL-C levels compared to Metacol after 90 days of supplementation.Read full original descriptionShow less
Randomized and Comparative Clinical Study on the Lipid-lowering Efficacy and Tolerability of Two Food Supplements in Mild Hypercholesterolemia
The primary outcome is to evaluate the effect of Cynacol on the change in LDL-C levels compared to Metacol after 90 days of supplementation.
The secondary outcomes are to evaluate:
- the change of TC, non-HDL cholesterol (non-HDL-C), apolipoprotein B (apoB), Tg, HDL-C levels after 90 days of supplementation with Cynacol compared to Metacol. The safety outcome is collection of the adverse events not related, related or possibly related to the study products.
Inclusion: age between 35-70 years; both genders; LDL-C levels between 115 and 190 mg/dl; subjects able to understand the informed consent and sign it before enrollment in the study.
Exclusion: taking hypolipidemic drugs or supplements that affect lipid metabolism; personal history of cardiovascular disease or equivalent risk factors; diabetes mellitus; known thyroid, liver, kidney or muscle diseases; any medical or surgical condition that makes patient compliance with the study protocol complex or inconsistent; any known allergy or hypersensitivity to one or more components of the food supplements; Tg levels ≥ 400 mg/dl; obesity [body mass index (BMI) ≥ 30 kg/m²].