Familial hypercholesterolaemia trials in Italy

In Italy 13 Also abroad 115

13 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Lipid Transport Disorder Italian Genetic Record (LIPIGEN)
Where
Sesto San Giovanni
People
15,000
Run by
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi)
See details and how to joinNCT06362473
Phase 2/3Taking people
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
Where
Piacenza, Rome
Age
6 years to 17 years
People
153 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07058077 · EU 2024-519068-42-00
Phase 3Not yet taking people in Italy
A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events
Where
Milan, Naples, Negrar
Age
18 years and over
People
103 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT07474649
Phase 3Taking people
Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies
Where
Milan, Modena, Roma
Age
2 years to 100 years
People
195 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05682378
No phaseNot yet taking people in Italy
Berberol P for Mild-to-Moderate Hypercholesterolaemia
Where
Guidonia Montecelio, Piacenza, Rome, Urbino
Age
18 years to 70 years
People
255
Run by
Liaquat University of Medical & Health Sciences
See details and how to joinNCT07789366
No phaseTaking people
Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administration on Coronary Plaque Volumes Measured by Coronary Computed Tomography Angiography (CCTA) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)
Where
Caserta, Catania, Cinisello Balsamo, Florence, Naples, Padova, Palermo, Roma, Torino
Age
12 years and over
People
52 worldwide
Run by
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi)
See details and how to joinNCT07447648
No phaseTaking people
Effects of Statins and Hormone Replacement Therapy in Coagulation Profile of Menopausal Women With Dyslipidemia
Where
Pisa
Age
45 years to 55 years
People
70
Run by
University of Pisa
See details and how to joinNCT07742488
Phase 3Taking people
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Where
Milan, Roma, Torino, Verona
Age
6 years to 11 years
People
60 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597019
No phaseTaking people
Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Bempedoic Acid in Italy
Where
Naples
Age
18 years and over
People
1,500
Run by
Federico II University
See details and how to joinNCT07374861
No phaseTaking people
Evaluation of Adherence, Persistence and Efficacy of Treatment With PCSK9 Inhibitors in Italy
Where
Arzignano, Bari, Caserta, Catanzaro, Eboli, Foggia, Genova, Lecce, Messina, Milan, Naples, Novara, Parma, Pescara, Rivoli, Roma, Salerno, Sassari, Siena, Torino
Age
18 years to 80 years
People
5,000
Run by
Federico II University
See details and how to joinNCT05430828
No phaseTaking people
Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Inclisiran in Italy
Where
Naples
Age
18 years and over
People
3,000
Run by
Federico II University
See details and how to joinNCT06287177
No phaseTaking people
Effect of Two Food Supplements on Lipid Profile in Patients With Mild Hypercholesterolemia
Where
Pavia
Age
35 years to 70 years
People
40
Run by
Fondazione IRCCS Policlinico San Matteo di Pavia
See details and how to joinNCT07295327
No phaseTaking people
Evaluation of the Effects of Two Dietary Supplement Formulations on the Lipid Profile in Mild Hypercholesterolemia
Where
Bologna
Age
18 years to 69 years
People
99
Run by
IBSA Farmaceutici Italia Srl
See details and how to joinNCT06810466