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Taking people in United StatesPhase 4

My Path to Quit Tobacco

Key facts

Who runs it
University of Wisconsin, Madison
Where
Indianapolis, Kansas City, Milwaukee, Phoenix, and Richmond, United StatesSee the 5 sites
Trial code
Status
Recruiting
Phase
Phase 4
People taking part
1,550 people, planned
Started
6 Jul 2026
Expected to end
Jan 2030
Type of study
Interventional, 3 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Nicotine patch
  • Quitline Counseling Phone Calls
  • Counseling Sessions
  • Pathways to Freedom
  • Monetary Incentive
Record updated
10 November 2026

Who can take part

Age
21 years and older
Sex
Women and men
Healthy volunteers
Can take part

The registry criteria, word for word

Show all 5 criteriaShow less

Who can take part

  • self-identify as Black
  • smoke cigarettes (greater than or equal to 1 cigarette on greater than or equal to 4 days/week)
  • motivated to quit smoking
  • willing to discontinue any non-study smoking cessation pharmacotherapy use during study treatment

Who cannot take part

  • currently taking bupropion for non-smoking cessation reasons

Where in United States

  • Indiana UniversityIndianapolis, United StatesContact: Megan Piper, PhDNot yet recruiting
  • University of Kansas Medical Center Research Institute, IncKansas City, United StatesContact: Megan Piper, PhDNot yet recruiting
  • UW School of Medicine and Public HealthMilwaukee, United StatesContact: Megan Piper, PhDTaking people
  • Arizona State UniversityPhoenix, United StatesContact: Megan Piper, PhDNot yet recruiting
  • Virginia Commonwealth UniversityRichmond, United StatesContact: Megan Piper, PhDNot yet recruiting

About the trial

What the trial wants to find out

The overarching goal of this program of research is to reduce smoking-related health disparities by increasing smoking cessation among Black adults. The goal of this research proposal is to determine whether more intensive, culturally specific, evidence-based interventions are more effective at promoting long-term cessation and other key patient-centered outcomes compared to the usual evidence-based standard of care: services provided by a state-run quitline. This study compares the relative effectiveness of three different treatments (Standard, Intensive, and Intensive Incentivized) on long-term smoking cessation (biochemically confirmed abstinence from combusted tobacco at 26-weeks post-target quit day) among Black adults who smoke and want to quit.

The 3 groups in the trial

  • Standard InterventionExisting treatment, for comparison

    The Standard Intervention will include 2 weeks of nicotine patches + 4 quitline-style counseling phone calls.

    Treatment: Nicotine patch and Quitline Counseling Phone Calls

  • Intensive InterventionTreatment being tested

    The Intensive Intervention will include 8 weeks of nicotine patches (if eligible) + 8 counseling sessions (choice of individual phone or virtual group) + the Pathways to Freedom video content on the study website with additional smoking cessation content.

    Treatment: Nicotine patch, Counseling Sessions, and Pathways to Freedom

  • Intensive Incentivized InterventionTreatment being tested

    The Intensive Incentivized Intervention will include all components provided in the Intensive intervention (8 weeks of nicotine patches (if eligible) + 8 counseling sessions (choice of individual phone or virtual group) + the Pathways to Freedom video content on the study website with additional smoking cessation content) and up to $50 for completing counseling sessions ($5 for completing sessions 1-6 and $10 for completing sessions 7 and 8)

    Treatment: Nicotine patch, Counseling Sessions, Pathways to Freedom, and Monetary Incentive

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Comparing Three Multicomponent Interventions to Help Adults Quit Smoking
Record updated
10 November 2026