Tests safety of human neural stem cells in Huntington's disease
Tests whether implanted hNSC-01 cells are safe for adults with Huntington's disease.
Plain-language title generated from the registry record
Registry title: Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease
Key facts
- Where
- Irvine, United StatesSee the site
- Phase
- Phase 1/2
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07451613, who can take part
Where in United States
- University of California, IrvineIrvine, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Leslie Thompson
- Trial code
- NCT07451613
- Record updated
- 13 April 2026
- Original description
The purpose of this research study is to determine whether an implantation of hNSC-01 is a safe and tolerable study intervention for Huntington's disease. This study is the first time that hNSC-01 is being tested in people.Read full original descriptionShow less
Phase 1B/2A Study of the Safety and Tolerability of Human Neural Stem Cells for Huntington's Disease
The purpose of this research study is to determine whether an implantation of hNSC-01 is a safe and tolerable study intervention for Huntington's disease. This study is the first time that hNSC-01 is being tested in people.
Inclusion: Have decision-making capacity and be able to provide written informed consent; Are between 18 to 65 years of age; Have genetically confirmed diagnosis of Huntington's Disease; Able to undergo MRI scans, tolerate neurosurgical procedure, blood draws and lumbar puncture.
Exclusion: Test positive for human immunodeficiency virus (HIV), hepatitis C or chronic hepatitis B at Screening; Are pregnant; Have an implanted deep brain stimulation device.
Please note this may not be a complete list of eligibility criteria.