Digital Neurotherapy and Coaching for Depression Symptoms in Polycystic Kidney Disease
Tests two non-drug approaches against education alone for depression in ADPKD.
Plain-language title generated from the registry record
Registry title: Managing Depressive Symptoms in ADPKD
Key facts
- Where
- Rochester, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT07745920, who can take part
Where in United States
- Mayo ClinicRochester, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mayo Clinic
- Trial code
- NCT07745920
- Record updated
- 7 August 2026
- Original description
The purpose of this research is to evaluate the feasibility and effectiveness of Digital Neurotherapy (DNT) or Capacity Coaching (CC) for managing symptoms of depression and self reported pain in Autosomal Dominant Polycystic Kidney Disease (ADPKD) compared to education alone.Read full original descriptionShow less
A Pilot Study for Managing Depressive Symptoms in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
The purpose of this research is to evaluate the feasibility and effectiveness of Digital Neurotherapy (DNT) or Capacity Coaching (CC) for managing symptoms of depression and self reported pain in Autosomal Dominant Polycystic Kidney Disease (ADPKD) compared to education alone.
Inclusion: Confirmed clinical diagnosis of ADPKD using Pei-Ravine criteria; Pre-End Stage Kidney Disease, with Stage 1-5 CKD (eGFR >10 ml/min/1.73m2, with no anticipated dialysis or transplant within 12 months); Clinical or self-diagnosis of depression; English-language fluency.
Exclusion: Anticipated dialysis or transplant within 6 months; Prior chronic dialysis; Prior organ (liver or kidney) transplant; Suicidal ideation/unstable mental illness of any kind; Significant cognitive impairment (Mini Mental Status Exam (MMSE)); eGFR <10 ml/min/1.73m2; Lack of access/ability to use internet-based programs; Lack of English language fluency.