Acute lymphoblastic leukaemia: open trials in Australia

23 open trials have a site in Australia. Registry data; only the trial team decides who can take part.

NCT06395103
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
Queensland Children's Hospital-Oncology & Haematology (Site 1996), Brisbane · Royal Children's Hospital-Children's Cancer Centre (Site 1994), Melbourne · Sydney Children's Hospital (Site 1997), Randwick
Registry updated 2026-10-30
NCT06124157
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
Trial Treatment · Phase 2 · National Cancer Institute (NCI)
John Hunter Children's Hospital, Hunter Regional Mail Centre · Royal Children's Hospital, Parkville · Perth Children's Hospital, Perth · Queensland Children's Hospital, South Brisbane
Registry updated 2026-10-27
NCT07155226
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
Trial Treatment · Phase 1/2 · AstraZeneca
Fitzroy · Perth
Registry updated 2026-10-23
NCT05327894
Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia
Trial Treatment · Phase 3 · Princess Maxima Center for Pediatric Oncology
North Adelaide- Womens and Childrens Hospital, Adelaide · Australian and New Zealand Children's Haematology/Oncology Group, Clayton · Monash Children's Hosptial, Clayton · New Lambton Heights- John Hunter Children's Hospital, New Lambton Heights · Royal Children's Hospital (Children's Cancer Centre), Parkville · Perth Children's Hospital, Perth · Queensland Children's Hospital, South Brisbane · Sydney Childrens Hospital, Sydney · The Childrens Hospital At Westmead, Westmead
Registry updated 2026-10-19
NCT07109219
Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia
Trial Treatment · Phase 1/2 · AstraZeneca
Melbourne
Registry updated 2026-10-15
NCT07387926
Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+) or ABL-class Ph-like Acute Lymphoblastic Leukemia (ALL)
Trial Treatment · Phase 1/2 · Novartis Pharmaceuticals
Sydney
Registry updated 2026-10-15
NCT06137118
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
Trial Treatment · Phase 1/2 · AstraZeneca
Melbourne
Registry updated 2026-10-13
NCT04065399
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Trial Treatment · Phase 1/2 · Syndax Pharmaceuticals
Alfred Hospital, Melbourne · Peter MacCallum Cancer Centre (PMCC), Melbourne · Sir Charles Gairdner Hospital, Nedlands · Royal Melbourne Hospital (RMH), Parkville · Royal North Shore Hospital, Saint Leonards
Registry updated 2026-10-09
NCT06514794
A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)
Trial Treatment · Phase 2 · Allotera Therapeutics
Peter Mac Callum Cancer Institute, Melbourne · Royal Children's Melbourne, Melbourne
Registry updated 2026-09-28
NCT03666000
Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)
Trial Treatment · Phase 1 · Imugene Limited
Royal Adelaide Hospital, Adelaide · Royal Prince Alfred Hospital, Camperdown · St Vincent's Hospital Melbourne, Fitzroy · Barwon Health - Andrew Love Cancer Centre, Geelong · Liverpool Hospital, Liverpool
Registry updated 2026-09-08
NCT01949129
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
Trial Treatment · Phase 2/3 · St. Anna Kinderkrebsforschung
Children's Cancer Centre The Royal Children's Hospital, Melbourne · Princess Margaret Hospital for Children, Perth · Sydney Children's Hospital, Randwick · Lady Cilento Children's Hospital, South Brisbane · The Children's Hospital at Westmead Oncology Unit, Sydney
Registry updated 2026-09-04
NCT04546399
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Trial Treatment · Phase 2 · National Cancer Institute (NCI)
John Hunter Children's Hospital, Hunter Regional Mail Centre · Perth Children's Hospital, Perth · Sydney Children's Hospital, Randwick · Queensland Children's Hospital, South Brisbane · The Children's Hospital at Westmead, Westmead
Registry updated 2026-09-01
NCT03959085
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
Trial Treatment · Phase 3 · Children's Oncology Group
Monash Medical Center-Clayton Campus, Clayton · John Hunter Children's Hospital, Hunter Regional Mail Centre · Women's and Children's Hospital-Adelaide, North Adelaide · Royal Children's Hospital, Parkville · Perth Children's Hospital, Perth · Royal Hobart Hospital, Saint Hobart · Queensland Children's Hospital, South Brisbane · The Children's Hospital at Westmead, Westmead
Registry updated 2026-08-25
NCT04726241
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Trial Treatment · Phase 1/2 · PedAL BCU, LLC
Royal Children's Hospital, Parkville · Perth Children's Hospital, Perth · Queensland Children's Hospital, South Brisbane · The Children's Hospital at Westmead, Westmead
Registry updated 2026-08-25
NCT07070219
A Study of CTD402 in T-ALL/LBL Patients
Trial Treatment · Phase 1/2 · Imviva Bio
Royal Prince Alfred, Sydney
Registry updated 2026-08-19
NCT07325305
Physical Activity and Exercise During Early Treatment Phases for Childhood Acute Lymphoblastic Leukaemia to Protect Against Muscle Loss and Improve Frailty Outcomes
Trial Treatment · Murdoch Childrens Research Institute
Royal Children's Hospital, Melbourne
Registry updated 2026-07-06
NCT01790152
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
Research · Children's Oncology Group
Perth Children's Hospital, Perth · Princess Margaret Hospital for Children, Perth
Registry updated 2026-05-18
NCT06051409
A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)
Trial Treatment · Phase 3 · Ascentage Pharma Group Inc.
Royal Adelaide Hospital, Adelaide · Alfred Health, Melbourne · Royal Perth Hospital, Perth · Royal North Shore Hospital, St Leonards
Registry updated 2026-04-30
NCT03590171
International Study for Treatment of High Risk Childhood Relapsed ALL 2010
Trial Treatment · Phase 2 · Charite University, Berlin, Germany
Australian & New Zealand Childhood Hematology & Oncology Group, Clayton
Registry updated 2026-03-17
NCT06166706
Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia
Research · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Perth Children's Hospital, Perth
Registry updated 2025-04-09
NCT03643276
Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017
Trial Treatment · Phase 3 · Martin Schrappe
Sydney Children's Hospital, Sydney · The Children's Hospital at Westmead, Westmead
Registry updated 2025-04-06
NCT05476770
Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
Trial Treatment · Phase 1 · Therapeutic Advances in Childhood Leukemia Consortium
Sydney Children's Hospital, Sydney · Children's Hospital at Westmead, Westmead
Registry updated 2024-12-06
NCT05509855
A Long-Term Safety Follow-Up Study for Patients Treat With WU-CART-007
Research · Allotera Therapeutics
Peter MacCullam Cancer Center, Melbourne
Registry updated 2024-11-20

All Acute lymphoblastic leukaemia trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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