Acute lymphoblastic leukaemia trials in Canada

In Canada 30 Also abroad 563

30 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 4Taking people
Asciminib Roll-over Study
Where
Montreal
Age
7 years to 100 years
People
347 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT04877522 · EU 2023-507557-16-00
No phaseTaking people
Pediatric Orthopaedic Implant Safety & Efficacy
Where
Vancouver
Age
0 years to 25 years
People
4,000
Run by
University of British Columbia
See details and how to joinNCT05361980
Phase 3Taking people
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
Where
Calgary, Halifax, Montreal, Ottawa, Winnipeg
Age
18 years to 39 years
People
303 worldwide
Run by
Alliance for Clinical Trials in Oncology
See details and how to joinNCT03150693
Phase 1/2Taking people
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Where
Calgary, Montreal, Toronto
Age
6 months to 25 years
People
90 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06395103 · EU 2023-507178-41-00
Phase 2/3Taking people
A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)
Where
Toronto
Age
12 years and over
People
340 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07570173 · EU 2025-522267-15-00
Phase 2Taking people
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
Where
Calgary, Edmonton, Halifax, Hamilton, Montreal, Québec, Sherbrooke, Toronto, Vancouver, Winnipeg
Age
366 days to 46 years
People
222 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06124157
Phase 1/2Taking people
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
Where
Montreal, Toronto
Age
16 years and over
People
85 worldwide
Run by
AstraZeneca
See details and how to joinNCT07155226 · EU 2025-521299-76-00
Phase 1/2Taking people
Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia
Where
Toronto, Vancouver
Age
12 years and over
People
83 worldwide
Run by
AstraZeneca
See details and how to joinNCT07109219 · EU 2025-522372-93-00
Phase 1Taking people
CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies
Where
Calgary, Ottawa, Toronto, Vancouver
Age
1 year and over
People
24
Run by
British Columbia Cancer Agency
See details and how to joinNCT06208735
Phase 3Taking people
Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies
Where
Fredericton, Montreal
Age
18 years and over
People
63 worldwide
Run by
CSL Behring
See details and how to joinNCT07648264 · EU 2026-525626-38-00
Phase 1/2Taking people
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
Where
Montreal, Toronto
Age
12 years and over
People
255 worldwide
Run by
AstraZeneca
See details and how to joinNCT06137118 · EU 2023-505840-20-00
Phase 1/2Taking people
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Where
Toronto
Age
30 days and over
People
447 worldwide
Run by
Syndax Pharmaceuticals
See details and how to joinNCT04065399 · EU 2024-513759-34-00
Phase 3Taking people
Study of Out of Specification for Tisagenlecleucel
Where
Hamilton, Montreal, Ottawa, Québec, Toronto
Age
0 years to 100 years
People
200 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT04094311
Phase 2/3Taking people
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
Where
Calgary, Montral, Montreal, Toronto, Vancouver, Winnipeg
Age
1 month to 18 years
People
1,800 worldwide
Run by
St. Anna Kinderkrebsforschung
See details and how to joinNCT01949129 · EU 2024-512657-24-00
Phase 2Taking people
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Where
Calgary, Edmonton, Halifax, Montreal, Québec, Sherbrooke, St. John's, Vancouver, Winnipeg
Age
1 year to 30 years
People
461 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT04546399
Phase 3Taking people
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
Where
Calgary, Edmonton, Halifax, Hamilton, Kingston, London, Montreal, Ottawa, Québec, Saskatoon, Sherbrooke, St. John's, Toronto, Vancouver, Winnipeg
Age
365 days to 25 years
People
5,951 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT03959085
Phase 1/2Taking people
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Where
Calgary, Edmonton, Halifax, London, Montreal, Ottawa, Québec, Sherbrooke, Toronto, Vancouver, Winnipeg
Age
Up to 22 years
People
960 worldwide
Run by
PedAL BCU, LLC
See details and how to joinNCT04726241
No phaseTaking people
A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
Where
London
Age
6 years to 39 years
People
330 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT05702645
Phase 2Not yet taking people in Canada
Subcutaneous Blinatumomab Plus Ponatinib for BCR-ABL+ B-ALL
Where
Edmonton
Age
18 years and over
People
80
Run by
University of Alberta
See details and how to joinNCT07301424
Phase 1/2Taking people
TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II
Where
Calgary, Edmonton, Hamilton, Montreal, Québec, Vancouver
Age
Up to 1 year
People
90 worldwide
Run by
Tanja Andrea Gruber
See details and how to joinNCT05848687
No phaseTaking people
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
Where
Calgary, Hamilton, Montreal, Ottawa, Québec, Toronto
People
420 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT01790152
Phase 1Not yet taking people in Canada
Phase I Clinical Trial of ThINKK Adoptive Immunotherapy After Allogeneic Hematopoietic Transplantation in Children With Leukemia or Neuroblastoma
Where
Montreal, Toronto
Age
2 years to 12 years
People
12
Run by
Michel Duval
See details and how to joinNCT07518654
Phase 1/2Taking people
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
Where
Calgary, Edmonton
Age
12 years and over
People
606 worldwide
Run by
Sumitomo Pharma America, Inc.
See details and how to joinNCT04988555
No phaseTaking people
Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease
Where
Edmonton
Age
10 years to 18 years
People
20
Run by
University of Alberta
See details and how to joinNCT06325280
No phaseTaking people
HIIT in Pediatric Heart Transplant Recipients (MedBIKE™)
Where
Edmonton
Age
10 years to 18 years
People
10
Run by
University of Alberta
See details and how to joinNCT05451979