Alzheimer disease: open trials in Spain

58 open trials have a site in Spain. Registry data; only the trial team decides who can take part.

NCT07011732
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Hospital General Universitario de Elche, Elche · Oroitu S.L., Getxo · Hospital Ruber Juan Bravo, Madrid · Hospital Clínico San Carlos, Madrid · Hospital Universitario Virgen de la Victoria, Málaga · Clínica Universidad de navarra, Pamplona · Hospital Universitario De Salamanca, Salamanca · Hospital Victoria Eugenia De La Cruz Roja Espanola, Sevilla · Consorci Sanitari de Terrassa, Terrassa · Hospital Universitario Rio Hortega, Valladolid · Clinica Montecanal S.L., Zaragoza
Registry updated 2026-11-06
NCT07213700
InRAD Observational Study
Research · Stichting International Registry for Alzheimer's Disease and other Dementias Foundation
Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona
Registry updated 2026-11-06
NCT07284472
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
Trial Treatment · Phase 2/3 · Exciva GmbH
Hospital Germans Trias i Pujol, Badalona · Hospital Clínico San Carlos, Madrid · Hospital San Juan de Dios De Sevilla, Sevilla · Hospital Universitario Rio Hortega, Valladolid · Complejo Asistencial de Zamora. Hospital Provincial de Zamora, Zamora
Registry updated 2026-11-06
NCT07688213
A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
Trial Treatment · Phase 2 · Sanofi
Barcelonabeta Brain Research Center, Barcelona · Hospital Universitari Vall d'Hebron, Barcelona · Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona · Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcón · Hospital Universitario Y Politecnico La Fe, Valencia · Clinica Montecanal S.L., Zaragoza
Registry updated 2026-11-06
NCT07781657
Study to Test Effects and Safety of RO7568282 in Early Symptomatic Alzheimer's Disease
Trial Treatment · Phase 2 · Hoffmann-La Roche
Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona · Hospital de la Santa Creu i Sant Pau, Barcelona · Policlinica Gipuzkoa S.A., Donostia · Hospital Universitario 12 de Octubre, Madrid · Hospital Clínico San Carlos, Madrid · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-11-06
NCT06159673
ACP-204 in Adults With Alzheimer's Disease Psychosis
Trial Treatment · Phase 2/3 · ACADIA Pharmaceuticals Inc.
Hospital Germans Trias i Pujol, Badalona · Hospital Universitario Regional de Málaga, Málaga · Hospital Universitario Virgen De La Macarena, Sevilla · Complejo Asistencial de Zamora. Hospital Provincial de Zamora, Zamora
Registry updated 2026-11-05
NCT07918417
Exercise in Alzheimer's Disease: Functional Biomarkers
Trial Treatment · European University Miguel de Cervantes
Miguel de Cervantes European University, Valladolid
Registry updated 2026-11-05
NCT06194799
ACP-204 in Adults With Alzheimer's Disease Psychosis Open Label Extension Study
Trial Treatment · Phase 3 · ACADIA Pharmaceuticals Inc.
Hospital Germans Trias i Pujol, Badalona · Hospital Universitario Regional de Málaga, Málaga · Hospital Universitario Virgen De La Macarena, Sevilla · Complejo Asistencial de Zamora. Hospital Provincial de Zamora, Zamora
Registry updated 2026-11-04
NCT06540833
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
Trial Treatment · Phase 2 · Intra-Cellular Therapies, Inc.
Hosp. Gral. de Albacete, Albacete · Hosp. Prov. de Zamora, Zamora · Hosp. Viamed Montecanal, Zaragoza
Registry updated 2026-11-03
NCT06651567
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia
Trial Treatment · Phase 2 · Intra-Cellular Therapies, Inc.
Hospital General Universitario de Albacete, Albacete · Hospital Germans Trias i Pujol, Badalona · Hospital Universitario de Getafe, Getafe · Hospital Quironsalud Malaga, Málaga · Complejo Asistencial de Zamora. Hospital Provincial de Zamora, Zamora · Clinica Montecanal S.L., Zaragoza
Registry updated 2026-11-03
NCT06585787
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Trial Treatment · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Hospital Universitari de Santa Maria, Lleida · Hospital Clínico San Carlos, Madrid · Hospital Universitario Puerta de Hierro de Majadahonda, Majadahonda · Hospital Quironsalud Malaga, Málaga · Hospital Universitario De Salamanca, Salamanca · Hospital Victoria Eugenia De La Cruz Roja Espanola, Sevilla · Hospital Universitario Rio Hortega, Valladolid · Clinica Montecanal S.L., Zaragoza
Registry updated 2026-10-27
NCT06976216
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Hospital Clinic de Barcelona, Barcelona · Hospital Universitari de Santa Maria, Lleida · Hospital Clínico San Carlos, Madrid · Clínica Universidad de navarra, Pamplona · Hospital Universitari General de Catalunya, Sant Cugat del Vallès · Hospital Victoria Eugenia De La Cruz Roja Espanola, Sevilla
Registry updated 2026-10-27
2023-506609-21-00
Sleep and body temperature as markers of progression of Alzheimer's disease in Down syndrome.
Trial Treatment · Phase 2 · Fundacio Institut De Recerca De L Hospital De La Santa Creu I Sant Pau
This trial only enrols participants with Down syndrome
Hospital de la Santa Creu i Sant Pau, Barcelona
Registry updated 2026-10-20
NCT07033494
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Hospital Clinic de Barcelona, Barcelona · Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona · Hospital del Mar, Barcelona · Fundacio Assistencial De Mutua De Terrassa Fpc, Terrassa
Registry updated 2026-10-20
NCT07177352
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Trial Treatment · Phase 3 · Hoffmann-La Roche
Fundación ACE, Barcelona · Hospital de la Santa Creu i Sant Pau, Barcelona · Hospital Vall d'Hebron, Barcelona · Hospital Universitario Reina Sofia, Córdoba · Hospital de Dénia;Servicio de Neurología, Denia · Policlínica Guipuzkoa, Donosti-San Sebastián · Hospital San Cecilio, Granada · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario de la Princesa, Madrid · Fundació Hospitalàries Martorell;Neurology, Martorell · Hospital Quiron de Madrid, Pozuelo de Alarcón · Hospital Virgen Del Rocio, Seville · Hospital Mutua De Terrasa, Terrassa · Hospital Universitario Dr. Peset, Valencia · Hospital Universitario la Fe, Valencia
Registry updated 2026-10-19
NCT05980949
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
Trial Treatment · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Hospital Clínico San Carlos, Madrid · Hospital Universitario Puerta de Hierro de Majadahonda, Majadahonda · Hospital Quironsalud Malaga, Málaga · Hospital Universitario De Salamanca, Salamanca · Hospital Victoria Eugenia De La Cruz Roja Espanola, Sevilla · Hospital Universitario Rio Hortega, Valladolid · Complejo Asistencial de Zamora. Hospital Provincial de Zamora, Zamora · Clinica Montecanal S.L., Zaragoza
Registry updated 2026-10-16
NCT06937229
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Hospital General Universitario de Elche, Elche · Oroitu S.L., Getxo · Hospital Clínico San Carlos, Madrid · Hospital Ruber Juan Bravo, Madrid · Hospital Universitario Virgen de la Victoria, Málaga · Clínica Universidad de navarra, Pamplona · Hospital Universitario De Salamanca, Salamanca · Hospital Victoria Eugenia De La Cruz Roja Espanola, Sevilla · Fundacio Assistencial De Mutua De Terrassa Fpc, Terrassa · Hospital Universitario Rio Hortega, Valladolid · Clinica Montecanal S.L., Zaragoza
Registry updated 2026-10-16
2024-517187-36-01
A Study of Treatments for the Prevention of Disease Progression in Individuals at Risk for or With Early Onset Alzheimer’s Disease Caused by a Genetic Mutation
Trial Treatment · Phase 2/3 · Washington University School Of Medicine
Hospital Clinic de Barcelona, Barcelona
Registry updated 2026-10-13
NCT07636811
A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Trial Treatment · Phase 2 · Alnylam Pharmaceuticals
This trial only enrols participants with Down syndrome
Hospital de la Santa Creu i Sant Pau, Barcelona · Gestion Hospitalaria Del Sur S.A., Dos Hermanas · Hospital Clínico San Carlos, Madrid · Hospital Universitario Regional de Málaga, Málaga · Clínica Universidad de navarra, Pamplona · Hospital Universitario Dr. Peset Aleixandre, Valencia
Registry updated 2026-10-13
NCT06976203
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona · Policlinica Gipuzkoa S.A., Donostia · Hospital Ruber Juan Bravo, Madrid · Hospital Universitario 12 de Octubre, Madrid · Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcón · Hospital Universitario Marqués de Valdecilla, Santander · Hospital Universitario Dr. Peset Aleixandre, Valencia
Registry updated 2026-10-08
NCT07214727
A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease
Trial Treatment · Phase 1 · Alnylam Pharmaceuticals
Hospital Clinic de Barcelona, Barcelona · Hospital Clínico San Carlos, Madrid · Hospital Universitari General de Catalunya, Sant Cugat del Vallès
Registry updated 2026-10-08
NCT00869817
Dominantly Inherited Alzheimer Network (DIAN)
Research · Washington University School of Medicine
Hospital Clinic Barcelona, Barcelona
Registry updated 2026-10-05
2025-524314-29-00
A study to learn about the effects of Trontinemab in participants at risk for Alzheimer‘s disease
Trial Treatment · Phase 3 · F. Hoffmann-La Roche AG
Hospital de la Santa Creu i Sant Pau, Barcelona · Barcelonabeta Brain Research Center, Barcelona · Hospital Clinic de Barcelona, Barcelona · Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona · Policlinica Gipuzkoa S.A., Donostia · Fundacion CITA Alzheimer, Donostia · Hospital Universitari de Santa Maria, Lleida · Hospital Universitario 12 de Octubre, Madrid · Foundation for Research on Neurological Diseases (Fundacion CIEN), Madrid · Clínica Universidad de navarra, Pamplona · Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcón · Hospital Universitario Marqués de Valdecilla, Santander · Hospital Universitari General de Catalunya, Sant Cugat del Vallès · University Hospital Virgen Del Rocio S.L., Sevilla · Hospital Universitario Y Politecnico La Fe, Valencia
Registry updated 2026-10-01
NCT07847944
Neuroprotective Effects of Oleanolic Acid and Erythrodiol in Prodromal Alzheimer's Disease
Trial Treatment · Spanish National Research Council
Instituto de la Grasa, CSIC, Seville
Registry updated 2026-09-29
NCT07698431
Personalized Brain Health Service and Dementia Prevention
Trial Treatment · Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Fundació Pasqual Maragall, Barcelona
Registry updated 2026-09-16

All Alzheimer disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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