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Amyloidosis: open trials in United States

67 open trials have a site in United States. Registry data; only the trial team decides who can take part.

  • NCT06128629

    MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

    Trial Treatment · Phase 3 · Intellia Therapeutics

    University of Michigan, Ann Arbor · Emory University School of Medicine, Atlanta · Johns Hopkins University, Baltimore · Boston University School of Medicine, Boston · Brigham and Women's Hospital, Boston · Medical University of South Carolina, Charleston · Northwestern University, Chicago · Cleveland Clinic, Cleveland · Ohio Health Research Institute, Columbus · University of Texas Southwestern Medical Center, Dallas · Baylor Scott & White Research Institute, Dallas · University of Colorado Denver, Denver · Barbara Ann Karmanos Cancer Institute, Detroit · Duke University Medical Center, Durham · Inova Fairfax Hospital, Falls Church · Baylor College of Medicine, Houston · Houston Methodist Hospital, Houston · Indiana University Health, Indianapolis · Mayo Clinic- Jacksonville, Jacksonville · St. Luke's Hospital, Kansas City · University of Kentucky Gill Heart Institute, Lexington · Cedars-Sinai Medical Center, Los Angeles · Western Greater Los Angeles VA Medical Center, Los Angeles · University of Wisconsin - Madison, Madison · Yale University School Of Medicine, New Haven · New York University (NYU) School of Medicine - Langone Medical Center, New York · Columbia University Medical Center, New York · Stanford University, Palo Alto · Penn Presbyterian Medical Center, Philadelphia · Allegheny General Hospital, Pittsburgh · University of Pittsburgh Medical Center, Pittsburgh · Baylor Scott and White - The Heart Hospital Baylor Plano, Plano · Oregon Health and Science university (OHSU), Portland · Virginia Commonwealth University - Department of Internal Medicine, Richmond · Mayo Clinic, Rochester · University of California, San Diego (UCSD) Medical Center, San Diego · University of Arizona, Tucson · MedStar Washington Hospital Center - MedStar Heart and Vascular Institute, Washington D.C. · Cleveland Clinic of Florida, Weston

    Registry updated 2026-11-04

  • NCT06978660

    Registry updated 2026-11-04

  • NCT05652335

    A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

    Trial Treatment · Phase 1 · Janssen Research & Development, LLC

    Levine Cancer Institute, Charlotte · Colorado Blood Cancer Institute, Denver · City of Hope, Duarte · MD Anderson Cancer Center, Houston · City of Hope Orange County Lennar Foundation Cancer Center, Irvine · Memorial Sloan-Kettering Cancer Center, New York · Icahn School of Medicine at Mt. Sinai, New York · University of Pennsylvania Division of Hematology Oncology Perelman Center for Advanced Medicine, Philadelphia · University of California San Francisco, San Francisco

    Registry updated 2026-11-03

  • NCT05974644

    Southeastern ATTR Amyloidosis Consortium: SEATTRAC Family Registry

    Research · Virginia Commonwealth University

    Virginia Commonwealth University, Richmond

    Registry updated 2026-11-03

  • NCT07224672

    A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Cyclophosphamide, Bortezomib, and Dexamethasone in Adult Participants With Newly Diagnosed Amyloid Light Chain (AL) Amyloidosis

    Trial Treatment · Phase 2 · GlaxoSmithKline

    Aurora · Boston · Hackensack · Los Angeles · Nashville · New Haven · Rochester · Salt Lake City

    Registry updated 2026-11-03

  • NCT07591038

    PET/CT Imaging in Carriers of TTR Mutations

    Research · University of Texas Southwestern Medical Center

    UT Southwestern Medical Center, Dallas

    Registry updated 2026-10-29

  • NCT01137643

    Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

    Research · UNC Lineberger Comprehensive Cancer Center

    Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, Chapel Hill

    Registry updated 2026-10-28

  • NCT07112924

    CCM OPEN HF Registry

    Research · Impulse Dynamics

    University of Michigan, Ann Arbor · Massachusetts General Hospital, Boston · Deborah Heart and Lung Center, Browns Mills · David Turbay, MD, El Paso · Texan Cardiovascular Institute, El Paso · The Stern Cardiovascular Foundation, Inc, Germantown · Hackensack University Medical Center, Hackensack · Heart House, Haddon Heights · University of Kansas Medical Center, Kansas City · Saint Luke's Hospital Mid America Heart Institute, Kansas City · Saint Luke's Hospital of Kansas City, Kansas City · Cardiovascular Specialists of New England Research Foundation, Londonderry · Centra Health, Inc. dba Stroobants Cardiovascular Center, Lynchburg · CardioVascular Associates of Mesa, Mesa · Advocate Aurora Health-St. Lukes, Milwaukee · Minneapolis Heart Institute Research Foundation, Minneapolis · Rutgers New Jersey Medical School/University Hospital, Newark · Henry Ford Providence Hospital, Novi · Oklahoma Heart Hospital Research Foundation, Oklahoma City · AdventHealth Orlando, Orlando · HonorHealth Research Institute, Phoenix · University of Arizona and Banner University Medical Center Phoenix, Phoenix · Legacy Medical Group Cardiology, Portland · Providence St. Vincent Medical Center, Portland · Peak Heart and Vascular, Surprise · AdventHealth Tampa, Tampa · CHRISTUS Trinity Mother Frances Health System, Tyler · PeaceHealth Southwest Medical Center, Vancouver · Reading Hospital, West Reading · Trinity Ann Arbor d/b/a Michigan Heart Ann Arbor, Ypsilanti

    Registry updated 2026-10-27

  • NCT07615270

    A Pilot Study of Anselamimab in Patients With AL Amyloidoma and Measurable Tissue Involvement

    Trial Treatment · Early phase 1 · Stanford University

    Stanford University, Palo Alto

    Registry updated 2026-10-27

  • NCT06365060

    Screening for AL Amyloidosis in Smoldering Multiple Myeloma

    Research · Tufts Medical Center

    University of Alabama Hospital, Birmingham · Tufts Medical Center, Boston · Atrium Health Levine Cancer Institute, Charlotte · The Ohio State University Comprehensive Cancer Center, Columbus · UT Southwestern, Harold C. Simmons Comprehensive Cancer Center, Dallas · UNC Lineberger Comprehensive Cancer Center, Durham · Cedars-Sinai Medical Center, Los Angeles · Columbia University Irving Medical Center, New York · Memorial Sloan-Kettering Cancer Center, New York · VCU Medical Center, Richmond · University of Utah, Huntsman Cancer Hospital, Salt Lake City · University of California San Francisco, San Francisco · Cleveland Clinic Florida, Weston Hospital, Weston

    Registry updated 2026-10-26

  • NCT07538518

    PET Imaging Study Using Evuzamitide to Detect Cardiac Amyloidosis in Patients With Inconclusive Nuclear Scans and Elevated TAD1 Levels

    Research · Lorena Saelices

    One Boston Medical Center Place, Boston · Bill and Rita Clements Advanced Medical Imaging Center, Dallas · Columbia University Irving Medical Center, New York

    Registry updated 2026-10-22

  • NCT06679946

    A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

    Trial Treatment · Phase 3 · Alnylam Pharmaceuticals

    Baltimore · Beverly Hills · Boston · Chicago · Cleveland · Columbus · Dallas · Durham · Glenview · Indianapolis · Kansas City · La Jolla · Nashville · New York · Omaha · Philadelphia · Phoenix · Rochester · Salt Lake City · Stanford · St Louis · Washington D.C.

    Registry updated 2026-10-21

  • NCT07207811

    CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

    Trial Treatment · Phase 3 · Novo Nordisk A/S

    Jefferson Health, Abington · LeHigh Valley Hospital, Allentown · University of Michigan Health System, Ann Arbor · Ascension Texas Cardiovascular Research Institute, Austin · St. Davids Heart and Vascular, Austin · John Hopkins Medicine, Baltimore · University of Maryland Medical Center (UMMC) - Children's Hospital (UMCH), Baltimore · Tufts Medical Center, Boston · Massachusetts General Hospital, Boston · Northwestern University Clinical and Translational Sciences Institute, Chicago · The University of Chicago Medicine, Chicago · The Carl and Edyth Lindner-Center for Research and Education at The Christ Hospital, Cincinnati · Cleveland Clinic Taussig Cancer Institute, Cleveland · OhioHealth Riverside Methodist Hospital, Columbus · Baylor Scott & White Research Institute - Annette C. and Harold C. Simmons Transplant Institute, Dallas · University of Texas Southwestern Medical Center, Dallas · Henry Ford Health, Detroit · Duke University Health System, Durham · Inova Fairfax Hospital - Inova Heart and Vascular Institute, Falls Church · Profound Research, Farmington Hills · UF Health Heart and Vascular Hospital, Gainesville · Northeast Georgia Heart Center, Pc (Nghc), Gainesville · Endeavor Health- Glenbrook Hospital, Glenview · Prisma Health, Greenville · Penn State Milton S.Hershey Medical Center - Penn State Hershey Cancer Institute, Hershey · The Queen's Medical Center, Honolulu · Baylor St. Luke Medical Center, Houston · Houston Methodist Hospital, Houston · Indiana University (IU) Health - Methodist Professional Center II, Indianapolis · Saint Luke's Hospital of Kansas City, Kansas City · University of California San Diego (UCSD) - Sulpizio Cardiovascular Center (SCVC), La Jolla · The Heart Group of Lancaster General Health, Lancaster · Cedars-Sinai Medical Center - Samuel Oschin Comprehensive Cancer Institute, Los Angeles · Keck School of Medicine USC - Healthcare Consultation Center 2 (HCCII), Los Angeles · North Shore University Hospital - Northwell Health, Manhasset · Intermountain Healthcare - Intermountain Medical Center - C. DuWayne Schmidt Chest Clinic, Murray · Saint Thomas Health, Nashville · Yale University School Of Medicine, New Haven · LCMC - LSU University Medical Center New Orleans LCMC Center, New Orleans · Mount SInai Medical Center, New York · Weill Medical College of Cornell University, New York · NYU Langone Health, New York · Columbia University Medical Center, New York · Sentara Cardiovascular Research Institute, Norfolk · University of Nebraska Medical Center, Omaha · UCI Medical Center, Orange · Profound Research LLC at Southern California Heart Specialists, Pasadena · Penn Medicine: University of Pennsylvania Health System, Philadelphia · Mayo Clinic in Arizona, Phoenix · Baylor Scott & White The Heart Hospital, Plano · Oregon Health and Science University, Portland · Virginia Commonwealth University Medical Center, Richmond · Mayo Clinic, Rochester · Laurelton Heart Specialist, PC, Rosedale · University of California San Francisco Medical Center, San Francisco · NorthBay Clinical Research, Santa Rosa · Providence Sacred Heart Medical Center and Children's Hospital, Spokane · Lucile Packard Children's Hospital, Stanford · Washington University School of Medicine, St Louis · Saint Louis University, St Louis · Yeshiva University - Albert Einstein College of Medicine - Montefiore Medical Center (MMC), The Bronx · Cardiology Associates Research, LLc, Tupelo · MedStar Heart & Vascular Institute (MHVI) - MedStar Washington Hospital Center, Washington D.C.

    Registry updated 2026-10-21

  • NCT07052903

    TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

    Trial Treatment · Phase 3 · Alnylam Pharmaceuticals

    Atlanta · Aurora · Austin · Baltimore · Boston · Brandon · Charleston · Charlotte · Charlottesville · Chicago · Cleveland · Columbus · Dallas · Detroit · Evanston · Falls Church · Gainesville · Houston · Indianapolis · Kansas City · Laguna Hills · La Jolla · Lancaster · Manhasset · Miami · New York · Norfolk · Norwich · Philadelphia · Plano · Portland · Richmond · Rochester · Salt Lake City · Seattle · Spokane · Stanford · St Louis · The Bronx · Tucker · Washington D.C.

    Registry updated 2026-10-20

  • NCT04561518

    ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

    Research · Alnylam Pharmaceuticals

    Austin · Baltimore · Boston · Columbus · Durham · Houston · Iowa City · Jacksonville · Kansas City · La Jolla · Los Angeles · New York · Philadelphia

    Registry updated 2026-10-13

  • NCT07583823

    Elevated Rate Pacing of Cardiac Amyloidosis

    Trial Treatment · University of Minnesota

    University of Minnesota, Minneapolis

    Registry updated 2026-10-13

  • NCT07358078

    DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

    Research · Alnylam Pharmaceuticals

    Beverly Hills · Boston · Charlotte · Dallas · Honolulu · Kansas City · La Jolla · Memphis · Naples · New Brunswick · Philadelphia · St Louis · Tucson

    Registry updated 2026-10-09

  • NCT05040373

    Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program

    Research · Alnylam Pharmaceuticals

    Iowa City

    Registry updated 2026-10-08

  • NCT07223203

    TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy

    Trial Treatment · Phase 3 · Alnylam Pharmaceuticals

    Aurora · Baltimore · Boston · Chapel Hill · Chicago · Dallas · Houston · Nashville · New York · Rochester

    Registry updated 2026-10-08

  • NCT05898646

    Daratumumab Maintenance Therapy for Improving Survival in Patients With Light Chain Amyloidosis, EMILIA Trial

    Trial Treatment · Phase 2 · Mayo Clinic

    Mayo Clinic in Rochester, Rochester · Mayo Clinic in Arizona, Scottsdale

    Registry updated 2026-10-01

  • NCT07285044

    Registry updated 2026-09-30

  • NCT07850284

    SMS-Based Remote Symptom Monitoring for Patients With Plasma Cell Disorders

    Research · Mayo Clinic

    Mayo Clinic in Rochester, Rochester

    Registry updated 2026-09-30

  • NCT06768489

    Registry updated 2026-09-25

  • NCT06465810

    Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

    Research · AstraZeneca

    Baltimore · Boston · Chicago · Dallas · Danville · Durham · Germantown · Greenville · Houston · Indianapolis · Kansas City · La Jolla · Los Angeles · Manhasset · Milwaukee · Nashville · New Brunswick · New Haven · New York · Philadelphia · Portland · Richmond · Rochester · San Francisco · Seattle · St Louis · Washington D.C.

    Registry updated 2026-09-23

  • NCT07654855

    Registry updated 2026-09-14

All Amyloidosis trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Amyloidosis trials in United States – Frontlight Research