Amyloidosis trials in United States

In United States 69 Also abroad 184

69 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis
Where
Eden Prairie
People
52,121 worldwide
Run by
AstraZeneca
See details and how to joinNCT06355934
No phaseTaking people
Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF
Where
Boston
Age
65 years and over
People
515
Run by
Massachusetts General Hospital
See details and how to joinNCT05577819
No phaseTaking people
Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers
Where
Cleveland, Dallas, New York
Age
30 years to 80 years
People
500
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT05489549
Phase 3Not yet taking people in United States
An Open-Label Study to Evaluate the Long-Term Safety and Efficacy of ALXN2220 in Adults With Transthyretin Amyloid Cardiomyopathy
Where
Atlanta, Aurora, Boston, Chapel Hill, Charleston, Cleveland, Columbus, Danville, Durham, Falls Church, Fort Worth, Greenville, Houston, Indianapolis, Irvine, Jacksonville, Kansas City, La Jolla, Madison, Memphis, New York, Palo Alto, Philadelphia, Portland, Richmond, Salt Lake City, San Francisco, Seattle, St Louis, Stony Brook, Washington D.C., Weston
People
1,180 worldwide
Run by
Alexion Pharmaceuticals, Inc.
See details and how to joinNCT07789483 · EU 2026-526755-57-00
No phaseTaking people
Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
Where
Boston, Chicago, Germantown, Jacksonville, Palo Alto, Portland
Age
18 years and over
People
500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07690436
Phase 4Taking people
Ultrasound Therapy In Cardiac Amyloidosis
Where
Boston
Age
18 years to 90 years
People
70
Run by
Brigham and Women's Hospital
See details and how to joinNCT04667494
Phase 1/2Taking people
Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis
Where
Dallas, Nashville, Salt Lake City
Age
18 years and over
People
37
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT05145816
Phase 1/2Taking people
Elranatamab in Patients With Relapsed or Refractory AL Amyloidosis
Where
Boston, Cleveland, New Haven
Age
18 years and over
People
49
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT06569147
Phase 1/2Taking people
A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis)
Where
Boston, Buffalo, Columbus, Denver, Detroit, Duarte, Houston, Nashville
Age
18 years and over
People
220 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT06292780 · EU 2023-507809-34-00
No phaseEnrolling by invitation
Prospective Evaluation of Artificial Intelligence-enabled Screening for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Where
New Haven
Age
18 years and over
People
150
Run by
Yale University
See details and how to joinNCT07398950
Phase 1Enrolling by invitation
PET Imaging With [18F]Fluselenamyl in People With Cardiac Amyloidosis
Where
St Louis
Age
18 years and over
People
50
Run by
Washington University School of Medicine
See details and how to joinNCT07771621
No phaseTaking people
Cardiovascular Multimodality Imaging Study
Where
The Bronx
Age
18 years and over
People
10,000
Run by
Montefiore Medical Center
See details and how to joinNCT06610019
Phase 2Not yet taking people in United States
Dose Schedule Study of BCMA Bispecific Antibody, Elranatamab, for Newly Diagnosed Immunoglobulin Light Chain (AL) Amyloidosis
Where
Cleveland, Rochester
Age
18 years and over
People
64
Run by
Case Comprehensive Cancer Center
See details and how to joinNCT07524634
Phase 3Taking people
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Where
Atlanta, Aurora, Austin, Baltimore, Boston, Charleston, Chicago, Cleveland, Dallas, Detroit, Durham, Falls Church, Greenville, Jacksonville, Kansas City, La Jolla, Los Angeles, Miami, New Brunswick, New Haven, New York, Philadelphia, Pittsburgh, Portland, Richmond, Rochester, Rosedale, Salt Lake City, San Francisco, Seattle, Stanford, St Louis, Washington D.C., Weston
Age
18 years to 75 years
People
587 worldwide
Run by
Eidos Therapeutics, a BridgeBio company
See details and how to joinNCT06563895 · EU 2024-513547-82-00
Phase 4Taking people
Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis
Where
St Louis
Age
18 years to 80 years
People
150 worldwide
Run by
Eidos Therapeutics, a BridgeBio company
See details and how to joinNCT07695701 · EU 2026-526068-19-00
Phase 1Taking people
A Phase 1 Study of 99mTc-p5+14 in Healthy Volunteers and Patients With AL or ATTR Systemic Amyloidosis
Where
Knoxville
Age
18 years and over
People
31
Run by
University of Tennessee Graduate School of Medicine
See details and how to joinNCT05951816
No phaseTaking people
Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases (EchoNet-Screening)
Where
Los Angeles
Age
18 years and over
People
300
Run by
Cedars-Sinai Medical Center
See details and how to joinNCT05139797
No phaseEnrolling by invitation
AI Echocardiographic Screening of Cardiac Amyloidosis
Where
Chicago, Los Angeles, Palo Alto, Portland
Age
22 years and over
People
500
Run by
Cedars-Sinai Medical Center
See details and how to joinNCT06664866
No phaseTaking people
CAPACITY (Cardiac Amyloidosis and Physical ACtivITY) Study
Where
Charlotte
Age
18 years and over
People
50
Run by
Wake Forest University Health Sciences
See details and how to joinNCT06096675
Phase 2Enrolling by invitation
124I-Evuzamitide PET/CT Imaging In Patients With Lumbar Spinal Stenosis and Carpal Tunnel Syndrome
Where
Knoxville
Age
60 years and over
People
40
Run by
University of Tennessee Graduate School of Medicine
See details and how to joinNCT06907849
Phase 3Taking people
[64Cu]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid Cardiomyopathy
Where
Boston
Age
18 years and over
People
20
Run by
Brigham and Women's Hospital
See details and how to joinNCT07560306
Phase 2Taking people
Teclistamab-Daratumumab in AL Amyloidosis
Where
Boston, Milwaukee, New York
Age
18 years to 100 years
People
25
Run by
Rajshekhar Chakraborty, MD
See details and how to joinNCT07110844
Phase 1/2Taking people
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
Where
Boston, Cleveland, Detroit, Nashville, New York, Phoenix, Rochester, San Francisco, St Louis, Tampa
Age
18 years and over
People
91 worldwide
Run by
Alexion Pharmaceuticals, Inc.
See details and how to joinNCT07081646
No phaseTaking people
Registry of Older Patients With Cancer
Where
Boone, Chapel Hill, Greenville, Hendersonville, Morehead City, New Bern, Raleigh
Age
65 years and over
People
3,000
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT01137825
No phaseTaking people
Dietary Reporting In The Amyloidoses
Where
Detroit
Age
18 years and over
People
40
Run by
Barbara Ann Karmanos Cancer Institute
See details and how to joinNCT05738005