Aortic stenosis trials in Canada

In Canada 21 Also abroad 232

21 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease
Where
Montreal
Age
18 years and over
People
2,130
Run by
McGill University Health Centre/Research Institute of the McGill University Health Centre
See details and how to joinNCT04464655
No phaseTaking people
Valve Performance of the SAPIEN 3 Ultra RESILIA Valve: A Prospective Registry With Central Echocardiography Analysis.
Where
Québec
Age
18 years to 80 years
People
150
Run by
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
See details and how to joinNCT06420830
No phaseTaking people
Systematic Ambulatory ECG Monitoring Following TAVI
Where
Québec
Age
18 years and over
People
754
Run by
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
See details and how to joinNCT07739316
Phase 4Not yet taking people in Canada
Application of TAVI at Experienced Interventional Cardiac Centers Without On-site Cardiac Surgery (ATLAS Study)
Where
Edmonton
Age
18 years and over
People
600
Run by
University of Alberta
See details and how to joinNCT06818006
No phaseTaking people
Clinical Monitoring Strategy Versus Electrophysiology-guided Algorithmic Approach With a New LBBB After TAVI
Where
Edmonton, Halifax, Hamilton, London, Montreal, Ottawa, Saint John, Sherbrooke
Age
18 years and over
People
250 worldwide
Run by
Montreal Heart Institute
See details and how to joinNCT03303612
No phaseTaking people
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
Where
Hamilton, Québec, Vancouver
People
200 worldwide
Run by
Edwards Lifesciences
See details and how to joinNCT05172973
No phaseTaking people
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
Where
Hamilton, Québec, Vancouver
People
1,234 worldwide
Run by
Edwards Lifesciences
See details and how to joinNCT05172960
No phaseEnrolling by invitation
ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation
Where
Montreal, Ottawa, Saint John, Toronto, Vancouver
Age
18 years and over
People
1,500 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT05932615
No phaseNot yet taking people in Canada
Same-Day Versus Standard Hospital Discharge After TAVI (HOME-TAVI)
Where
Québec
Age
18 years and over
People
764 worldwide
Run by
Hospital Clinic of Barcelona
See details and how to joinNCT07738575
No phaseTaking people
A Study of Transcatheter Aortic Valve Replacement Case Selection and Valve Sizing Using the ABC Bicuspid Sizing Algorithm
Where
Calgary, Halifax, Hamilton, Newmarket, Ottawa, Québec, Toronto
People
290 worldwide
Run by
World Health Research Inc.
See details and how to joinNCT06991517
Phase 2/3Taking people
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
Where
Montreal, Québec, Winnipeg
Age
50 years and over
People
1,276 worldwide
Run by
Kardigan, Inc.
See details and how to joinNCT07001800 · EU 2025-522176-86-01
Phase 2Taking people
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Where
Cambridge, Montreal, North York, Ottawa, Québec
Age
50 years to 80 years
People
502 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05646381 · EU 2022-502135-19-00
No phaseTaking people
MiECC Versus Conventional Cardiopulmonary Bypass in Cardiac Surgery (MiECS)
Where
Toronto
Age
18 years to 85 years
People
1,300 worldwide
Run by
Aristotle University Of Thessaloniki
See details and how to joinNCT05487612
No phaseTaking people
Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR
Where
Québec
Age
18 years and over
People
310 worldwide
Run by
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
See details and how to joinNCT05459233
No phaseTaking people
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
Where
Hamilton, Vancouver
Age
65 years and over
People
2,250 worldwide
Run by
Edwards Lifesciences
See details and how to joinNCT04889872
No phaseTaking people
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement
Where
Edmonton, Halifax, Hamilton, Montreal, New Westminster, Ottawa, Regina, Saint John, Sherbrooke, Toronto, Vancouver, Winnipeg
People
4,000 worldwide
Run by
University of British Columbia
See details and how to joinNCT04634240
No phaseTaking people
Effect of Fetal Aortic Valvuloplasty on Outcomes
Where
Toronto
Age
23 weeks to 31 weeks
People
200 worldwide
Run by
Queen Silvia Children's Hospital, Gothenburg, Sweden
See details and how to joinNCT05386173
Phase 4Taking people
Angiotensin Receptor Blockers in Aortic Stenosis
Where
Québec
Age
20 years to 99 years
People
144 worldwide
Run by
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
See details and how to joinNCT04913870 · EU 2024-518389-28-00
No phaseTaking people
The Role of Cardiac Mechanics, Biomarkers and Frailty in Aortic Stenosis
Where
Montreal
Age
18 years and over
People
450
Run by
Christine Henri
See details and how to joinNCT02856620
No phaseTaking people
Translational-Omics in Aortic Stenosis (TOmAS) Biobank
Where
Montreal
Age
19 years and over
People
10,000
Run by
McGill University Health Centre/Research Institute of the McGill University Health Centre
See details and how to joinNCT05930899
No phaseTaking people
PARTNER 3 Trial - Aortic Valve-in-Valve
Where
Vancouver
People
125 worldwide
Run by
Edwards Lifesciences
See details and how to joinNCT03003299