Aortic stenosis trials in Germany

In Germany 36 Also abroad 232

36 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseNot yet taking people in Germany
Validation Of anatomY-specific Aortic Valve Implantation Guided by Software Using EncantoR
Where
Bad Nauheim, Bad Oeynhausen, Berlin, Dortmund, Dresden, Frankfurt, Hamburg, Kiel, Leipzig, München
Age
18 years and over
People
300 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT07696182
No phaseTaking people
Observational Study to Collect Data of Patient Which Recieving a TAVI in TAVI Procedure
Where
Freiburg im Breisgau
Age
18 years and over
People
300
Run by
IHF GmbH - Institut für Herzinfarktforschung
See details and how to joinNCT07215143
No phaseTaking people
Multicenter Study for the Validation of Willem AI: Aortic StenoSis Early Diagnosis With AI-electrocardiogram Study
Where
Bonn, Munich
Age
18 years and over
People
5,000
Run by
Idoven 1903 S.L.
See details and how to joinNCT07479992
No phaseTaking people
SYMmetric Valve fraME Expansion To Reduce hYpoattenuated Leaflet Thickening After Balloon-expandable TAVI: the SYMMETRY Trial
Where
Düsseldorf
Age
70 years and over
People
422 worldwide
Run by
Erasmus Medical Center
See details and how to joinNCT07872020
No phaseEnrolling by invitation
ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation
Where
Bad Nauheim, Cologne, Dortmund, Frankfurt, Kiel, München, Ulm
Age
18 years and over
People
1,500 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT05932615
No phaseTaking people
Non-Interventional Study on the Prevalence of Cardiac Amyloidosis in Patients With Higher-Grade Aortic Valve Stenosis - Evaluation Using Echocardiography, Computed Tomography, Tc99-SPECT/CT and Cardiac Magnetic Resonance Imaging (CMR)
Where
Tübingen
Age
18 years and over
People
600
Run by
University Hospital Tuebingen
See details and how to joinNCT07752732
No phaseNot yet taking people in Germany
Balloon- Versus Self-Expanding Intraannular TAVI in Small Aortic Annuli
Where
Hamburg
Age
18 years and over
People
510
Run by
Universitätsklinikum Hamburg-Eppendorf
See details and how to joinNCT07794306
No phaseEnrolling by invitation
Transfemoral TAVI With or Without Coronary Angiogram in Patients With Severe Aortic Stenosis (PURE TAVI)
Where
Düsseldorf, Essen, Freiburg im Breisgau, Lübeck, Ulm
Age
18 years and over
People
620 worldwide
Run by
Rede Optimus Hospitalar SA
See details and how to joinNCT06898086
No phaseTaking people
LANDMARK Trial: a Randomised Controlled Trial of Myval THV
Where
Bad Krozingen, Bad Nauheim, Braunschweig, Dresden, Hamburg, Leipzig, Regensburg
Age
18 years and over
People
988 worldwide
Run by
Meril Life Sciences Pvt. Ltd.
See details and how to joinNCT04275726
No phaseTaking people
Prospective, Long-term Evaluation of the SAPIEN 3 Ultra RESILIA Valve
Where
Bad Oeynhausen
Age
18 years and over
People
500
Run by
Institut für Pharmakologie und Präventive Medizin
See details and how to joinNCT06953206
Phase 3Taking people
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Where
Frankfurt am Main
Age
2 years to 11 years
People
9 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597006
No phaseTaking people
Post-Market Clinical Follow Up Study With Navitor Valve
Where
Bad Bevensen, Berlin, Cologne, Dortmund, Erlangen, Frankfurt, Hamburg, Kiel, München, Rostock, Ulm
Age
18 years to 100 years
People
1,000 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT06008080
Phase 3Taking people
PROTamine Application in patients underGOing tRAnScatheter aortic valve replacement (PROTAGORAS)
Where
Augsburg, Munich
Age
18 years and over
People
954 worldwide
Run by
Klinikum der Universitaet Muenchen AöR
See details and how to join2024-512024-10-01
No phaseTaking people
Mechanisms Of Disease Progression in Aortic Stenosis - the MODAS Study
Where
Bonn, Cologne, Düsseldorf
Age
18 years and over
People
938
Run by
Heinrich-Heine University, Duesseldorf
See details and how to joinNCT05851209
Phase 2Taking people
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Where
Ahaus, Berlin, Bonn, Dresden, Essen, Frankfurt am Main, Hamburg, Kaiserslautern, Leipzig, Mannheim, Muenster, Munich, Oldenburg
Age
50 years to 80 years
People
502 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05646381 · EU 2022-502135-19-00
Phase 4Taking people
Personalized, CT-guided Antithrombotic Therapy Versus Lifelong Single Antiplatelet Therapy to Reduce Thromboembolic and Bleeding Events in Non-atrial Fibrillation Patients After Transcatheter Aortic Valve Implantation
Where
Tübingen
Age
18 years to 110 years
People
2,500 worldwide
Run by
St. Antonius Hospital
See details and how to joinNCT06168370 · EU 2023-504637-42-01
Phase 3Taking people
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Where
Frankfurt am Main, Freiburg im Breisgau, Hanover
Age
6 years to 11 years
People
60 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597019
No phaseTaking people
Surgical vs Transcatheter Aortic Valve Replacement in YOUNG Patients
Where
Frankfurt, Hamburg, München, Trier
Age
65 years to 75 years
People
1,180 worldwide
Run by
Ceric Sàrl
See details and how to joinNCT06861361
No phaseNot yet taking people in Germany
Valvosoft Outcomes Registry for Real-World Evidence
Where
Hamburg, Kiel
Age
18 years and over
People
200 worldwide
Run by
Cardiawave SA
See details and how to joinNCT07520591
No phaseTaking people
MiECC Versus Conventional Cardiopulmonary Bypass in Cardiac Surgery (MiECS)
Where
Coswig, Göttingen, Ulm
Age
18 years to 85 years
People
1,300 worldwide
Run by
Aristotle University Of Thessaloniki
See details and how to joinNCT05487612
Phase 4Taking people
Impact of Beta-blocker on Outcome Among Patients Undergoing Transcatheter Aortic Valve Replacement (B-TAVR)
Where
Bad Krozingen, Bad Nauheim, Bad Oeynhausen, Giessen, Kiel
Age
18 years and over
People
498 worldwide
Run by
University Hospital, Basel, Switzerland
See details and how to joinNCT06472934 · EU 2024-518731-11-00
No phaseTaking people
VRAP-Heart - Virtual Reality Assisted Patient Empowerment for Interventions in Structural Heart Disease
Where
Cologne, Düsseldorf
Age
18 years and over
People
300
Run by
Heinrich-Heine University, Duesseldorf
See details and how to joinNCT05552352
No phaseTaking people
Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure
Where
Freiburg im Breisgau, Mainz, Tübingen
Age
18 years and over
People
1,000 worldwide
Run by
Semmelweis University
See details and how to joinNCT07016477
No phaseTaking people
Effect of Fetal Aortic Valvuloplasty on Outcomes
Where
Bonn, Heidelberg, Munich
Age
23 weeks to 31 weeks
People
200 worldwide
Run by
Queen Silvia Children's Hospital, Gothenburg, Sweden
See details and how to joinNCT05386173
No phaseTaking people
MYVAL Transcatheter Heart Valve System - Prospective German Multicenter Registry
Where
Lübeck
Age
18 years and over
People
2,000
Run by
Prof. Dr. med. Ingo Eitel
See details and how to joinNCT06804148