Asthma trials in United States

In United States 148 Also abroad 509

115 of 148 trials · From ClinicalTrials.gov, checked 14 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
Where
Amarillo, Baltimore, Baytown, Brooksville, Colorado Springs, Columbia, Dallas, Doral, Flint, Gainesville, Gastonia, Glenview, Hialeah, Houston, Kendall, Kerrville, Lewisville, McKinney, Miami, Miami Lakes, North Dartmouth, North Miami, Northridge, Olive Branch, Palm Springs, Pasadena, Rancho Cucamonga, Rincon, Riverton, Tampa, The Bronx, Towson, Valencia, West Hills, Winston-Salem
Age
12 years to 80 years
People
786 worldwide
Run by
Generate Biomedicines
See details and how to joinNCT07276724 · EU 2025-521950-41-00
Phase 3Taking people
Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment
Where
Ann Arbor, Aurora, Bethesda, Cleveland, Durham, Northfield, Salt Lake City, The Bronx
Age
6 years and over
People
230 worldwide
Run by
AstraZeneca
See details and how to joinNCT07444567
Phase 3Taking people
A Study to Investigate the Efficacy and Safety of GSK5784283 Compared With Placebo in Participants With Uncontrolled Asthma (PERSIST ASTHMA-2)
Where
Albuquerque, DuBois, Houston, Humble, Miami, Miami Lakes, Philadelphia, San Diego, Southfield, Tampa, Tomball
Age
12 years to 80 years
People
370 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07782996
Phase 3Taking people
A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma
Where
Ann Arbor, Atlanta, Baltimore, Boston, Chapel Hill, Cincinnati, Cleveland, Columbia, Coppell, Dallas, Detroit, Frisco, Hawthorne, Houston, La Jolla, Little Rock, Long Beach, Montgomery, Northfield, Oklahoma City, Orange, Phoenix, San Antonio, San Diego, Savannah, Schenectady, Staten Island, Temple, Toledo
Age
5 years to 11 years
People
231 worldwide
Run by
AstraZeneca
See details and how to joinNCT06023589
Phase 3Taking people
Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
Where
Albany, Albuquerque, Anchorage, Atlanta, Austin, Baytown, Beaumont, Bellaire, Bellingham, Boston, Burke, Burlington, Charleston, Charlotte, Cincinnati, Columbus, Corpus Christi, Corsicana, Cortland, Dallas, Dayton, Denver, Destin, Detroit, Durham, Ellicott City, El Paso, Fayetteville, Findlay, Frisco, Gilbert, Hawthorne, Hollis, Houston, Huntington Beach, Indianapolis, Jacksonville, Kansas City, Kendall, Kerrville, Lafayette, Lanham, Largo, Lincoln, Little Rock, Long Beach, Louisville, Madera, Mankato, McKinney, Meridian, Miami, Mission Viejo, Missoula, Moreno Valley, Nashville, Newark, New Orleans, New York, Normal, Northfield, Ocean City, Oklahoma City, Omaha, Orange, Orlando, Overland Park, Paramus, Pembroke Pines, Phoenix, Pittsburgh, Redondo Beach, River Forest, Riverside, Rochester, Rock Hill, San Antonio, San Diego, San Francisco, Silver Spring, Sioux Falls, Snellville, St Louis, Tampa, The Bronx, Toledo, Tyler, Vancouver, Vestal, Watertown, West Jordan, Westminster, White Marsh, Wilmington, Yukon
Age
12 years to 17 years
People
440 worldwide
Run by
AstraZeneca
See details and how to joinNCT06307665
Phase 1Taking people
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation
Where
Boston
Age
18 years to 50 years
People
313
Run by
Benjamin Medoff
See details and how to joinNCT00595491
Phase 2Taking people
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
Where
Ann Arbor, Boerne, Champaign, Chandler, Charlotte, Colorado Springs, Cypress, Dallas, DuBois, East Point, Edmond, Gastonia, Henderson, Hendersonville, Houston, Huntersville, Kansas City, Lancaster, McKinney, Mobile, New Brunswick, Newport Beach, Northridge, Oklahoma City, Richmond, Riverdale, Rock Hill, San Jose, St Louis, Toledo, Tulsa, Walnut Creek
Age
18 years to 75 years
People
252 worldwide
Run by
Pfizer
See details and how to joinNCT06977581 · EU 2024-517866-40-00
Phase 2Taking people
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
Where
Boston, Colorado Springs, Doral, Kirkland, Las Vegas, Nashville, Newport Beach, New York, Northridge, Ocala, Owensboro, Pensacola, Pittsburgh, Rolling Hills Estates, Tampa, Tempe, Westchester
Age
18 years to 75 years
People
531 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07219173
Phase 3Taking people
A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a)
Where
Aventura, Columbia, Cypress, Henderson, Medford, Miami, Naples, Owensboro, Spartanburg, Tomball
Age
18 years and over
People
110 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07645248
Phase 4Not yet taking people in United States
Novel Method for Removal of Orally Deposited Inhaled Fluticasone Propionate
Where
Madison
Age
18 years and over
People
20
Run by
University of Wisconsin, Madison
See details and how to joinNCT07664527
Phase 3Taking people
A Study to Learn About the Study Medicine Called Tilrekimig ( PF-07275315) in People With Severe Asthma
Where
Austin, Dallas, Edinburg, El Paso, Hannibal, McAllen, Oklahoma City, Pittsburgh, River Forest, The Bronx, Tomball
Age
12 years to 80 years
People
1,100 worldwide
Run by
Pfizer
See details and how to joinNCT07869043
No phaseNot yet taking people in United States
Reducing Exposure With Air Cleaners and Technology
Where
Berkeley, San Francisco
Age
13 years and over
People
100
Run by
University of California, Berkeley
See details and how to joinNCT07914010
No phaseNot yet taking people in United States
Asthma Ctrl SMART Trial
Where
Aurora, Cincinnati
Age
12 years to 18 years
People
389
Run by
Children's Hospital Medical Center, Cincinnati
See details and how to joinNCT07512622
Phase 2Taking people
Rademikibart IV for Acute Asthma and COPD Exacerbation
Where
Miami, St Louis
Age
18 years to 85 years
People
40
Run by
Connect Biopharm LLC
See details and how to joinNCT07705737
Phase 3Taking people
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)
Where
Bakersfield, Colchester, Dayton, Fall River, Houston, Inglewood, Kansas City, Lancaster, Miami, New York, Oklahoma City, Orlando, Rock Hill, San Antonio, Southfield, St Louis, Sugar Land, Tamarac, Tampa, West Covina, Williamsburg, Ypsilanti
Age
12 years to 80 years
People
786 worldwide
Run by
Generate Biomedicines
See details and how to joinNCT07359846
No phaseNot yet taking people in United States
Bilevel Positive Airway Pressure (BPAP) for Severe Asthma
Where
Columbus, New York, Philadelphia
Age
5 years to 17 years
People
36
Run by
Columbia University
See details and how to joinNCT07582211
Phase 1Taking people
A Study to Learn How Different Amounts of the Study Medicine Called PF-08103402 Are Tolerated and Act in the Body in Healthy Adults or Adults With Mild To-moderate Asthma
Where
New Haven
Age
18 years to 65 years
People
133 worldwide
Run by
Pfizer
See details and how to joinNCT07660731 · EU 2026-526260-21-00
No phaseNot yet taking people in United States
Artificially Intelligent Robot Control
Where
Miami
Age
4 years and over
People
80
Run by
University of Miami
See details and how to joinNCT07738016
Phase 2Taking people
A Study of JNJ-95597528 in Participants With Inadequately Controlled Moderate to Severe Asthma
Where
Boston, Edmond, Minneapolis, Oklahoma, St Louis, The Bronx, Westminster
Age
18 years to 85 years
People
440 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07746687 · EU 2026-526262-24-00
Phase 2Taking people
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
Where
Asheville, Austin, Bakersfield, Bellevue, Bellingham, Boerne, Boise, Cutler Bay, Dallas, DuBois, Edmond, El Paso, Farmington Hills, Forney, Grand Island, Grants Pass, Greenville, Hialeah, Horseheads, Huntersville, Huntington Beach, Hutchinson, Kansas City, Kings Mountain, Kingwood, Knoxville, La Mesa, Leesburg, Loma Linda, Long Beach, Louisville, Maspeth, McKinney, Medford, Miami, Miami Lakes, Millville, Milwaukee, Mullica Hill, Newport Beach, Noblesville, Omaha, Orlando, Palmetto Bay, Philadelphia, Pinehurst, Portland, Rock Hill, Roy, San Jose, Smithfield, St Louis, Sugar Land, Tampa, Toledo, Toms River, Victoria, Warren, West Des Moines, White Marsh, Wilmington, Winter Park, Worcester
Age
18 years to 75 years
People
540 worldwide
Run by
AstraZeneca
See details and how to joinNCT06932263 · EU 2024-519116-14-00
Phase 3Taking people
A Study to Learn About the Study Medicine Called Tilrekimig in People With Severe Asthma
Where
Bakersfield, Baytown, Flint, Garland, Mesquite, Miami, Monroe, Smyrna, Southfield, Tulsa, Union City, Victoria, White Marsh
Age
12 years to 80 years
People
1,100 worldwide
Run by
Pfizer
See details and how to joinNCT07772921 · EU 2026-526565-18-00
No phaseNot yet taking people in United States
R34 Asthma Depression
Where
New York
Age
60 years and over
People
60
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT07895576
No phaseTaking people
BREATHE: An Efficacy-implementation Trial Among Black Adults With Uncontrolled Asthma
Where
Beacon, Brooklyn
Age
18 years and over
People
400
Run by
Columbia University
See details and how to joinNCT05341726
Phase 4Taking people
Ventilation and Perfusion in Asthmatics
Where
Miami
Age
18 years to 75 years
People
40
Run by
University of Miami
See details and how to joinNCT07426458
Phase 2Taking people
Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma
Where
Austin, Bellevue, Charleston, Detroit, Edmond, El Paso, Los Angeles, McKinney, Melbourne, Miami, Pittsburgh, Richfield, Richmond, San Antonio, San Jose, Spartanburg, St Louis, Stow, Toledo, Tyler, White Marsh
Age
18 years to 75 years
People
600 worldwide
Run by
Windward Bio
See details and how to joinNCT07120503 · EU 2025-521391-58-00