Atrial fibrillation trials in Canada

In Canada 48 Also abroad 723

48 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
Where
Edmonton, Greater Sudbury, Hamilton, Longueuil, Moncton, Montreal, Oshawa, Québec, Rimouski, Scarborough Village, Sherbrooke, Terrebonne, Trois-Rivières, Victoria
Age
18 years and over
People
1,200 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07175428
Phase 3Taking people
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
Where
Hamilton, Longueuil, Sherbrooke
Age
18 years and over
People
15,364 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07626411 · EU 2025-521617-97-00
No phaseNot yet taking people in Canada
Paroxysmal Atrial Fibrillation Repeat Ablation Strategies With Durably Isolated Pulmonary Veins
Where
Ottawa
Age
18 years and over
People
60
Run by
Ottawa Heart Institute Research Corporation
See details and how to joinNCT07910825
No phaseTaking people
PULSED AF Post-Approval Study
Where
London, Montreal, Toronto
Age
18 years and over
People
580 worldwide
Run by
Medtronic Cardiac Ablation Solutions
See details and how to joinNCT06578104
Phase 2Taking people
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
Where
Calgary, Halifax, Hamilton, London, Montreal, Newmarket, Québec, Sherbrooke, Toronto, Vancouver
Age
18 years and over
People
165 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07217067
No phaseTaking people
Renal Denervation in Patients With Atrial Fibrillation and Hypertension
Where
London
Age
18 years and over
People
10
Run by
Pavel Antiperovitch
See details and how to joinNCT07893821
No phaseTaking people
Pericardiotomy in Cardiac Surgery
Where
Halifax, Hamilton, Montreal, Toronto
Age
18 years and over
People
1,400 worldwide
Run by
Population Health Research Institute
See details and how to joinNCT06486636
No phaseTaking people
Treating Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: Ablation or Medication
Where
Halifax, Hamilton, London, Montreal
Age
18 years and over
People
84
Run by
Nova Scotia Health Authority
See details and how to joinNCT07272902
No phaseTaking people
PulseSelect™ PFA Global Registry
Where
Montreal, Vancouver
Age
18 years and over
People
1,950 worldwide
Run by
Medtronic Cardiac Ablation Solutions
See details and how to joinNCT06393920
Phase 3Taking people
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
Where
Hamilton
Age
18 years and over
People
2,628 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07430956 · EU 2025-521618-25-00
Phase 3Taking people
ReVeRA-301: Etripamil in Atrial Fibrillation Phase 3
Where
Montreal
Age
18 years and over
People
750 worldwide
Run by
Milestone Pharmaceuticals Inc.
See details and how to joinNCT06716021 · EU 2024-516251-40-01
No phaseTaking people
BoxX-NoAF Clinical Trial
Where
Hamilton, London, Montreal, New Westminster
Age
65 years and over
People
960 worldwide
Run by
AtriCure, Inc.
See details and how to joinNCT06989775
No phaseTaking people
Surgical Ablation of AF Efficacy Trial
Where
Hamilton
Age
18 years and over
People
2,000
Run by
Population Health Research Institute
See details and how to joinNCT05434819
Phase 4Taking people
COmparison of Bleeding Risk Between Rivaroxaban and Apixaban in Patients With Atrial Fibrillation
Where
Gatineau, Halifax, Kingston, Laval, Montreal, Ottawa, Victoria
Age
18 years and over
People
3,018
Run by
Ottawa Hospital Research Institute
See details and how to joinNCT04642430
Phase 4Taking people
Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill Patients
Where
Ajax, Bowmanville, Oshawa, Toronto
Age
16 years and over
People
3,853
Run by
Scarborough General Hospital
See details and how to joinNCT07173855
No phaseTaking people
Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias
Where
Edmonton, Kitchener, Montreal, Newmarket
Age
18 years and over
People
20,000 worldwide
Run by
Heart Rhythm Clinical and Research Solutions, LLC
See details and how to joinNCT04088071
No phaseTaking people
The Fourth Left Atrial Appendage Occlusion Study
Where
Burlington, Calgary, Cambridge, Hamilton, Kitchener, London, Montreal, Newmarket, Ottawa, Québec, Regina, Saskatoon, Sherbrooke, St. Catharines, Toronto, Vancouver, Winnipeg
Age
18 years and over
People
4,000 worldwide
Run by
Hamilton Health Sciences Corporation
See details and how to joinNCT05963698
No phaseNot yet taking people in Canada
WSO BEAT STROKE Initiative
Where
London
Age
18 years and over
People
2,400
Run by
Luciano A. Sposato
See details and how to joinNCT06606054
No phaseTaking people
Safety of Perioperative Anticoagulation Management in People With Active Cancer Undergoing Cancer-Related Surgery or Procedures (ACE-HIGH Study)
Where
Ottawa
Age
18 years and over
People
700
Run by
Ottawa Hospital Research Institute
See details and how to joinNCT07372716
Phase 3Taking people
Short Term Anti-aRrhythmic Therapy for Post-Operative AF in Cardiac Surgery Patients Pilot Trial
Where
Hamilton, Toronto
Age
18 years and over
People
400
Run by
Population Health Research Institute
See details and how to joinNCT05841056
No phaseTaking people
Randomized Controlled Trial- Ablation Strategy for Paroxysmal Atrial Fibrillation - Trigger and Substrate Guided Wide Area Radiofrequency Ablation Compared to Pulsed Field Ablation Pulmonary Vein Isolation
Where
Montreal, Ottawa
Age
18 years and over
People
556
Run by
Ottawa Heart Institute Research Corporation
See details and how to joinNCT04823299
No phaseTaking people
Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral Anticoagulation
Where
Hamilton, London
Age
18 years and over
People
2,000 worldwide
Run by
Javelin Medical
See details and how to joinNCT05723926
No phaseTaking people
Testing VIRTUES Patient Care Sets in Cardiac Patients (VIRTUES Cardiac Care)
Where
London
Age
18 years and over
People
2,000
Run by
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
See details and how to joinNCT05452356
No phaseTaking people
Anteroposterior Versus Anterolateral Electrode Position for Electrical Cardioversion of Atrial Fibrillation
Where
Hamilton, Montreal, Québec, Toronto
Age
18 years and over
People
1,750
Run by
McMaster University
See details and how to joinNCT05511389
No phaseTaking people
Predicting Development of SCAF in Device Patients
Where
Ottawa
Age
18 years and over
People
500
Run by
Ottawa Heart Institute Research Corporation
See details and how to joinNCT02808260