Atrial fibrillation: open trials in United States
145 open trials have a site in United States. Registry data; only the trial team decides who can take part.
NCT07175428
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
Trial Treatment · Phase 2 · Regeneron Pharmaceuticals
PharmaTex Research, Amarillo · Health Sciences Research Building II, Atlanta · Grady Health System, Atlanta · Beth Israel Lahey Health-Beth Israel Deaconess Medical Center (BIDMC), Boston · Alpine Research TC, Clinton · Valley Clinical Trials, Inc., Covina · Nouvelle Clinical Research LLC, Cutler Bay · SEC Clinical Research, Dothan · North Coast Cardiology, Encinitas · Eastern Shore Research Institute, Fairhope · Profound Research, Millennium Cardiology, Farmington Hills · AA Medical Research Center (MRC), Flint · Mission Cardiovascular Research Institute, Fremont · Anderson Medical Research, Ft. Washington · Moses Cone Hospital Operating Corporation dba Cone Health, Lebauer-Brodie Center for Cardiovascular Research, Greensboro · National Institute of California Heart and Vein Specialists, Huntington Beach · Indiana University, Indianapolis · Franciscan Physician Network, Indiana Heart Physicians, Indianapolis · Blue Coast Research Center, LLC, Indianapolis · East Coast Institute for Research, Jefferson City, Jefferson City · NSC Research, Inc, Johns Creek · Fairview Health Services, Maplewood · K&R Research LLC, Marion · Advanced Medical Research, Maumee · Texas Institute of Cardiology PA, McKinney · Complete Heart Care P.A., McKinney · South Florida Research Organization LLC, Medley · Indiana Medical Research, Merrillville · Inpatient Research Clinic LLC, Miami Lakes · Synergy Group Medical, LLC, Missouri City · Permian Research Foundation, Odessa · Profound Research LLC at Southern California Heart Specialists, Pasadena · Empire Clinical Research, Pomona · Monument Health Clinical Research, Rapid City · The Cardiovascular Center, Redding · Reid Physician Associates, Richmond · Northbay Clinical Research Center, Santa Rosa · Cardiovascular Center of Sarasota Foundation for Research and Education, Sarasota · Tyler Cardiovascular Consultants, Tyler · Cardiology Associates Medical Group, Ventura · Interventional Cardiology Medical Group, West Hills · Monroe Research, LLC, West Monroe · Clinical Site Partners, LLC dba Flourish Research, Winter Park
Registry updated 2026-11-05
NCT07552272
Hummingbird ICE Study
Research · Philips Clinical & Medical Affairs Global
Cooper Hospital, Camden · Henry Ford Hospital, Detroit
Registry updated 2026-11-05
NCT07626411
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
Trial Treatment · Phase 3 · Regeneron Pharmaceuticals
Advanced Cardiovascular, Alexander City · PharmaTex Research, Amarillo · Morehouse School of Medicine, Atlanta · Atlanta Clinical Research Centers, Atlanta · Profound Research, Cardiology and Vascular Associates (CAVA) - Bloomfield Hills, Bloomfield Hills · Excel Medical Clinical Trials, dba Flourish Research, Boca Raton · PanAmerican Clinical Research, Brownsville · Alpine Research TC, Clinton · Hawthorne Health, Moose Pharmacy of Concord, Concord · Valley Clinical Trials, Inc., Covina · Nouvelle Clinical Research LLC, Cutler Bay · SEC Clinical Research, Dothan · Eastern Shore Research Institute, Fairhope · Lillestol Research, LLC, Fargo · Profound Research, Millennium Cardiology, Farmington Hills · Flint Clinical Research, Flint · K2 Medical Research, Foxboro, Foxborough · Mission Cardiovascular Research Institute, Fremont · Anderson Medical Research, Ft. Washington · West Valley Clinical Trials, Glendale · Peters Medical Research, High Point · Profound Research, Advanced Cardiovascular Care + Electrophysiology Clinic, Hobart · Synergy Groups Medical, Houston · West Houston Area Clinical Trial Consultants, LLC, Houston · National Institute of California Heart and Vein Specialists, Huntington Beach · Alliance Clinical Los Angeles, Inglewood · Nature Coast Clinical Research - Inverness, Inverness · NSC Research, Inc, Johns Creek · Profound Research LLC at San Diego Cardiovascular Associates, La Jolla · Arkansas Cardiology P.A., Little Rock · Carient Heart & Vascular, Manassas · K&R Research LLC, Marion · Advanced Medical Research, Maumee · South Florida Research Organization LLC, Medley · Synergy Group Medical, LLC, Missouri City · Cardiovascular Research of Northwest Indiana, LLC, Munster · Profound Research, Powers Health Medical Group - Electrophysiology, Munster · Radin Cardiovascular Medical Group, Newport Beach · Healix Clinical Research, New Smyrna Beach · Valley Clinical Trials, LLC dba Flourish Research, Northridge · Permian Research Foundation, Odessa · Southern California Heart Specialists, Pasadena · Sec Clinical Research, Pensacola · Monument Health Clinical Research, Rapid City · Flourish Research, St. Johns Center for Clinical Research, Saint Augustine · FOMAT - Comprehensive Cardiovascular Care, Santa Maria · Cardiovascular Center of Sarasota Foundation for Research and Education, Sarasota · Scottsdale Clinical Trials, Scottsdale · Super Health Pharmacy, Staten Island · Tennessee Center for Clinical Trials, Tullahoma · Tyler Cardiovascular Consultants, Tyler · Cardiology Associates Medical Group, Ventura · Conquest Research, Vienna · Interventional Cardiology Medical Group, West Hills · Monroe Research, LLC, West Monroe · Clinical Site Partners, LLC dba Flourish Research, Winter Park
Registry updated 2026-11-05
NCT07227532
A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System
Trial Treatment · Biosense Webster, Inc.
Aurora Denver Cardiology Associates, Aurora · Texas Cardiac Arrhythmia Research Foundation, Austin · The Christ Hospital, Cincinnati · Henry Ford Health System, Detroit · Baylor Scott and White Research Institute, Fort Worth · OC Memorial, Fountain Valley · University of Iowa Hospitals and Clinics, Iowa City · Mayo Clinic in Florida, Jacksonville · Mercy Hospital, Janesville · University of Kansas Medical Center, Kansas City · Northwell Health Physician Partners Cardiology, Lake Success · HCA Florida Mercy Hospital, Miami · Edward Hospital Midwest Cardiovascular Institute, Naperville · Orlando Health Heart and Vascular Institute, Orlando · The Kansas City Heart Rhythm Institute, Overland Park · Phoenix Cardiovascular Research Group, Phoenix · Baylor Scott & White Research Institute at The Heart Hospital Baylor Plano, Plano · Mayo Clinic - Rochester, Rochester · Springfield Medical Center, Springfield · Albert Einstein College of Medicine - Montefiore Medical Center, The Bronx · Capital Health Regional Medical Center, Trenton · Tucson Medical Center Pima Heart and Vascular, Tucson · Community Memorial Hospital, Ventura · Winchester Medical Center, Winchester · Trinity Health, Ypsilanti
Registry updated 2026-11-04
NCT05836987
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
Trial Treatment · Phase 3 · Johns Hopkins University
Presbyterian Healthcare Services, Albuquerque · University of New Mexico Health Sciences Center, Albuquerque · Emory University, Atlanta · University of Colorado, Aurora · Texas Cardiac Arrhythmia Research Foundation, Austin · Johns Hopkins University, Baltimore · Brigham and Women's Hospital, Boston · Tufts Medical Center, Boston · Boston Medical Center, Boston · Beth Israel Deaconess Medical Center, Boston · BMC - Brighton, Boston · St. Elizabeth's Medical Center, Boston · Mass General Hospital, Boston · University at Buffalo, Buffalo · Lahey Hospital & Medical Center, Burlington · University of North Carolina, Chapel Hill · Medical University of South Carolina, Charleston · University of Virginia, Charlottesville · Rush University Medical Center, Chicago · Northwestern University, Chicago · University of Chicago, Chicago · University of Illinois Chicago, Chicago · Loyola University Chicago, Chicago · The Lindner Center for Research and Education at The Christ Hospital, Cincinnati · University of Cincinnati College of Medicine, Cincinnati · BayCare Health Systems, Clearwater · MUSC Health Heart and Vascular, Columbia · OhioHealth Research Institute, Columbus · Ohio State University Medical Center, Columbus · University of Texas Southwestern Medical Center, Dallas · Henry Ford Health, Detroit · Essentia Health The Duluth Clinic, Duluth · Alexian Brothers Health System, Elk Grove Village · NorthShore University HealthSystem, Evanston · Advanced Heart and Vascular Institute of Hunterdon, Flemington · University of Florida, Gainesville · Trinity Health Grand Rapids/Mercy Health, Grand Rapids · Corewell Health (Former Spectrum Health), Grand Rapids · Hackensack Meridian Health, Hackensack · Baylor College of Medicine, Houston · Houston Methodist Hospital, Houston · University of Texas Health Science Center at Houston, Houston · Ascension St. Vincent, Indianapolis · University of Iowa Hospitals and Clinics, Iowa City · Mayo Clinic, Jacksonville · University Health Truman Medical Center, Kansas City · South Denver Cardiology Associates, P.C., Littleton · University of California Los Angeles (UCLA) Health, Los Angeles · University of Southern California Keck School of Medicine, Los Angeles · University of Wisconsin, Madison · University of Miami - Leonard S. Miller SOM, Miami · Medical College of Wisconsin/ Froedtert Hospital, Milwaukee · University of Minnesota, Minneapolis · Hennepin Healthcare Research Institute, Minneapolis · Minneapolis Heart Institute Foundation, Minneapolis · Midwest Cardiovascular Institute, Naperville · Columbia University Medical Center, New York · NYU Langone Health, New York · Weill Medical College of Cornell University, New York · University of Oklahoma Health Sciences Center, Oklahoma City · Cardiology Consultants of Philadelphia, Paoli · Thomas Jefferson University, Philadelphia · Banner University, Phoenix · Rutgers, the State University of New Jersey, Piscataway · Allegheny-Singer Research Institute, Pittsburgh · Rhode Island Hospital, Providence · NewYork Presbyterian - Queens, Queens · Virginia Commonwealth University, Richmond · James River Cardiology, Richmond · The Valley Hospital Inc., Ridgewood · William Beaumont Hospital, Royal Oak · UC Davis Health, Sacramento · University of Utah, Salt Lake City · Scripps Health, San Diego · Kaiser Permanente, San Francisco · Sarasota Memorial Health Care System, Sarasota · Maine Medical Partners MaineHealth Cardiology, Scarborough · Stanford University, Stanford · Staten Island University Hospital-Northwell Health, Staten Island · Washington University School of Medicine, St Louis · Stony Brook University, Stony Brook · Cleveland Clinic Florida, Stuart · St. Joseph Medical Center Tacoma, Tacoma · Westchester Medical Center, Valhalla · Georgia Arrhythmia Consultants and Research Institute, Warner Robins · Medical Faculty Associates George Washington University, Washington D.C. · White Plains Hospital, White Plains · Wake Forest Baptist Health, Winston-Salem · Baycare Health Systems Clearwater, Winter Haven · Wooster Community Hospital, Wooster · UMass Chan Medical School, Worcester · Penn State Health Medical Group Berks Cardiology, Wyomissing · Trinity Health Michigan Heart - Ann Arbor, Ypsilanti
Registry updated 2026-11-03
NCT07523750
A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation
Trial Treatment · Biosense Webster, Inc.
Emory Saint Joseph's Hospital, Atlanta · Texas Cardiac Arrhythmia Research Foundation, Austin · Beth Israel Deaconess Medical Center, Boston · Massachusetts General Hospital, Boston · OC Medical Center, Fountain Valley · St. Vincents Medical Center, Jacksonville · Arrhythmia Research Group, Jonesboro · Baptist Health Lexington, Lexington · HCA Florida Mercy Hospital, Miami · Intermountain Medical Center, Murray · NCH Healthcare, Naples · Rutgers, Robert Wood Johnson Medical School, New Brunswick · Lenox Hill Hospital, New York · Baylor Research Institute, Plano · WakeMed Hospital, Raleigh · Rochester General Hospital, Rochester · Memorial Health University Medical Center, Savannah · Montefiore Medical Center, The Bronx · Community Memorial Hospital, Ventura · Trinity Health Michigan Heart - Ann Arbor Campus, Ypsilanti
Registry updated 2026-11-03
NCT07527299
A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation
Trial Treatment · Biosense Webster, Inc.
JFK Medical Center, Atlantis · Aurora Denver Cardiology Associates, Aurora · Grandview Medical Center, Birmingham · Saint Elizabeth Medical Center, Edgewood · Hartford Hospital, Hartford · Mercy Hospital, Janesville · Arrhythmia Research Group, Jonesboro · Oklahoma Heart Hospital, Oklahoma City · Penn Presbyterian Medical Center, Philadelphia · Pacific Heart Institute Cedars Sinai Medical Center, Santa Monica · Albert Einstein College of Medicine - Montefiore Medical Center, The Bronx · Munson Medical Center, Traverse City · PIMA Heart and Vascular, Tucson
Registry updated 2026-11-03
NCT05724121
Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax
Research · National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-10-29
NCT06578104
PULSED AF Post-Approval Study
Research · Medtronic Cardiac Ablation Solutions
AnMed Health Center, Anderson · Piedmont Heart Institute, Atlanta · Medical University of South Carolina (MUSC), Charleston · University of Virginia Medical Center, Charlottesville · Endeavor Health - Swedish Hospital, Chicago · Bethesda North Hospital, Cincinnati · The Ohio State University -Wexner Medical Center, Columbus · Texas Health Research & Education Institute, Dallas · Doylestown Health Cardiology a division of Doylestown Health Physicians, Doylestown · Duke University Medical Center (DUMC), Durham · Southcoast Health System, Fall River · Mount Carmel Grove City Medical Center, Grove City · Northwell Health- Lenox Hill Hospital, New York · The Valley Hospital, New York · Nebraska Medical Center, Omaha · Beaumont Health System, Royal Oak · University of South Florida Health (USF), Tampa · Confluence Health Hospital Central Campus, Wenatchee · Pikeville Medical Center, Whitesburg
Registry updated 2026-10-28
NCT07217067
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
Trial Treatment · Phase 2 · Novartis Pharmaceuticals
Cooper University Hospital, Camden · Duke Univ Medical Center, Durham · Intermountain Medical Center, Murray · Weill Cornell Medical Center, New York · Swedish Heart and Vascular Clinic, Seattle · Cardiology Associates of North MS, Tupelo
Registry updated 2026-10-28
NCT07671677
BOdygUardian MOnitoriNg for ReCurrencE of AF
Research · Heart Rhythm Clinical and Research Solutions, LLC
Arrhythmia Center of South Florida, Delray Beach · University of Iowa Hospitals and Clinics, Iowa City · HCA Research Institute (FL Mercy Miami), Miami · Allegheny General Hospital, Pittsburgh · St. Mark's Hospital, Salt Lake City
Registry updated 2026-10-28
NCT07647939
Exclusion of Left Atrial Appendage Thrombus in Emergency Department Patients With Atrial Fibrillation Undergoing CT to Assess for Pulmonary Embolus: A Feasibility Study
Trial Treatment · Northwell Health
North Shore University Hospital, Manhasset
Registry updated 2026-10-26
NCT07651852
Globe Registry: Globe® Pulsed Field System Registry Study for Treating Patients With Symptomatic Atrial Fibrillation
Research · Kardium Inc.
Overlake Hospital, Bellevue · Arrhythmia Research Group, Jonesboro
Registry updated 2026-10-26
NCT07788040
Intracardiac Echocardiography Catheter Supply-Chain Reliability and Clinical Access Study
Research · Truway Health, Inc.
Truway Health, Inc., New York
Registry updated 2026-10-26
NCT07575269
Evaluation of the FARAFLEX Mapping and Pulsed Field Ablation System in Subjects With Atrial Fibrillation
Trial Treatment · Boston Scientific Corporation
Emory Saint Joseph's Hospital, Atlanta · Texas Cardiac Arrhythmia Research, Austin · Massachusetts General Hospital-Hospital, Boston · Trident Medical Center, Charleston · OhioHealth Research and Innovation Institute-Riverside Methodist Hospital, Columbus · Arrhythmia Research Group, Jonesboro · Pinnacle Health at Harrisburg Hospital - UPMC Pinnacle, Mechanicsburg · Mount Sinai Medical Center-Hospital, New York · Christus Trinity Mother Frances Health System-Hospital, Tyler · Mercy Hospital Medical Center, West Des Moines
Registry updated 2026-10-23
NCT06486636
Pericardiotomy in Cardiac Surgery
Trial Treatment · Population Health Research Institute
Baylor College of Medicine, Houston · University of Louisville, Louisville · Weill Cornell Medicine, New York
Registry updated 2026-10-21
NCT07275151
Repeatable Evaluation of Functional Intra-procedural Signals for Effect in Pulsed Field Ablation REFINE-PFA
Research · CathVision ApS
The Valley Hospital, Paramus · Trinity Health Ann Arbor Hospital, Ypsilanti
Registry updated 2026-10-21
NCT04703166
Tulane iPredict, Prevent Study to Evaluate the Progression of Atrial Myopathy.
Research · Tulane University School of Medicine
Tulane University School of Medicine, New Orleans
Registry updated 2026-10-20
NCT07625215
A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation
Trial Treatment · Phase 2 · Bayer
UCHealth University of Colorado Hospital - Cardiology, Aurora · Massachusetts General Hospital - Cardiology, Boston · Henry Ford Hospital - Cardiology, Detroit · Duke University Hospital - Cardiology, Durham · Texas Health Heart and Vascular Specialists - Fort Worth, Fort Worth · M Health Fairview Heart Clinic - Maplewood, Maplewood · UCSF Advanced Heart Failure Comprehensive Care Center, San Francisco · CHRISTUS Trinity | Mother Frances Louis and Peaches Owen Heart Hospital - Electrophysiology Clinic, Tyler
Registry updated 2026-10-20
NCT07883629
Comparison of Two Pulse Field Ablation Systems for AF Ablation
Trial Treatment · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Allegheny General Hospital, Pittsburgh
Registry updated 2026-10-20
NCT07298473
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)
Trial Treatment · Medtronic Cardiac Ablation Solutions
Piedmont Heart Institute, Atlanta · University of Alabama at Birmingham (UAB) Hospital, Birmingham · Massachusetts General Hospital, Boston · Cleveland Clinic Foundation, Cleveland · OhioHealth Research and Innovation Institute (OHRI), Columbus · Texas Cardiac Arrhythmia Research Foundation, Dallas · Inova Fairfax Hospital, Falls Church · Texas Health Fort Worth, Fort Worth · Kansas City Heart Rhythm Institute (Midwest Heart and Vascular Specialist), Kansas City · Scripps Green Hospital, La Jolla · Cedars-Sinai Medical Center, Los Angeles · Centra Medical Group Stroobants Cardiovascular Center, Lynchburg · NCH Rooney Heart Institute, Naples · Vanderbilt University Medical Center, Nashville · Northwell Health Lenox Hill Hospital, New Hyde Park · Sentara Norfolk General Hospital, Newport News · NYU Langone Health, New York · AdventHealth Cardiovascular Research Institute, Orlando · Hospital of the University of Pennsylvania, Philadelphia · Allegheny General Hospital, Pittsburgh · Memorial Health University Medical Center, Savannah · Montefiore Medical Center, The Bronx
Registry updated 2026-10-19
NCT07287436
Elite AF IDE Trial (Elite AF)
Trial Treatment · Boston Scientific Corporation
Sanger Heart and Vascular Institute / Atrium Health, Charlotte · Arrhythmia Research Group, Jonesboro
Registry updated 2026-10-16
NCT07874763
Bachmann's Bundle Versus Right Atrial Appendage Pacing
Trial Treatment · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Allegheny General Hospital, Pittsburgh
Registry updated 2026-10-16
NCT07430956
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
Trial Treatment · Phase 3 · Regeneron Pharmaceuticals
PharmaTex Research, Amarillo · AnMed Health, Anderson · Atlanta Clinical Research Centers, Atlanta · Profound Research, Cardiology and Vascular Associates (CAVA) - Bloomfield Hills, Bloomfield Hills · PanAmerican Clinical Research, Brownsville · Hawthorne Health, Moose Pharmacy of Concord, Concord · Southwest Family Medicine Associates, Dallas · SEC Clinical Research, Dothan · Profound Research, Millennium Cardiology, Farmington Hills · AA Medical Research Center (MRC), Flint · Flint Clinical Research, Flint · Mission Cardiovascular Research Institute, Fremont · Sun City Clinical Research, Glendale · Synergy Groups Medical, Houston · East Texas Cardiology, Houston · Synergy Group Medical,LLC, Houston · National Institute of California Heart and Vein Specialists, Huntington Beach · Franciscan Physician Network, Indiana Heart Physicians, Indianapolis · Jackson Heart Clinic, Jackson · East Coast Institute for Research, Jacksonville, Jacksonville · NSC Research, Inc, Johns Creek · Profound Research LLC at San Diego Cardiovascular Associates, La Jolla · Arkansas Cardiology P.A., Little Rock · Heart Institute of East Texas, Lufkin · K&R Research LLC, Marion · Texas Institute of Cardiology PA, McKinney · South Florida Research Organization LLC, Medley · Indiana Medical Research, Merrillville · Synergy Group Medical, LLC, Missouri City · Profound Research, Powers Health Medical Group - Electrophysiology, Munster · Valley Clinical Trials, LLC dba Flourish Research, Northridge · Profound Research LLC at Southern California Heart Specialists, Pasadena · Sec Clinical Research, Pensacola · Monument Health Clinical Research, Rapid City · FOMAT - Comprehensive Cardiovascular Care, Santa Maria · Cardiovascular Center of Sarasota Foundation for Research and Education, Sarasota · Super Health Pharmacy, Staten Island · Tennessee Center for Clinical Trials, Tullahoma · Cardiology Associates Medical Group, Ventura · Conquest Research, Vienna · Interventional Cardiology Medical Group, West Hills · Monroe Research, LLC, West Monroe · Clinical Site Partners, LLC dba Flourish Research, Winter Park
Registry updated 2026-10-14
NCT05116384
Renal Denervation + PVI vs PVI Alone for Persistent AF
Trial Treatment · University of Rochester
University of Rochester, Short Hills
Registry updated 2026-10-13
All Atrial fibrillation trials and the map
This page is not medical advice. Talk to your doctor before contacting a trial.