Atrial fibrillation trials in United States

In United States 146 Also abroad 724

146 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Bachmann's Bundle Versus Right Atrial Appendage Pacing
Where
Pittsburgh
Age
18 years and over
People
334
Run by
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
See details and how to joinNCT07874763
No phaseTaking people
Renal Denervation + PVI vs PVI Alone for Persistent AF
Where
Short Hills
Age
18 years and over
People
50
Run by
University of Rochester
See details and how to joinNCT05116384
No phaseTaking people
Prospective Remapping With Concomitant Left Atrial Appendage Occlusion to Ensure Durable Electroporation Study
Where
Bay Shore
Age
18 years and over
People
50
Run by
Northwell Health
See details and how to joinNCT07620262
Phase 3Taking people
ReVeRA-301: Etripamil in Atrial Fibrillation Phase 3
Where
Haddon Heights, Littleton, Manhattan, West Hills
Age
18 years and over
People
750 worldwide
Run by
Milestone Pharmaceuticals Inc.
See details and how to joinNCT06716021 · EU 2024-516251-40-01
No phaseTaking people
BoxX-NoAF Clinical Trial
Where
Ann Arbor, Atlanta, Austin, Baltimore, Charleston, Chicago, Cincinnati, Clearwater, Cleveland, Dallas, Grand Rapids, Jonesboro, Louisville, Manhasset, Marietta, Naples, Nashville, New York, Orlando, Pittsburgh, Rochester, San Antonio, San Diego, Sarasota, Scottsdale, St. Helena, St Louis, Toledo, Wausau, Ypsilanti
Age
65 years and over
People
960 worldwide
Run by
AtriCure, Inc.
See details and how to joinNCT06989775
No phaseTaking people
Volunteers to Investigate Best Results for Ablation and Novel Therapies for Atrial Fibrillation
Where
San Francisco
Age
18 years and over
People
1,125
Run by
University of California, San Francisco
See details and how to joinNCT05504356
No phaseEnrolling by invitation
Hypertension and Arrhythmias in CLL Patients Treated With BTK Inhibitors
Where
Philadelphia
Age
22 years and over
People
50
Run by
Abramson Cancer Center at Penn Medicine
See details and how to joinNCT06211413
Phase 3Taking people
Optimal Anti-Thrombotic Management Following Percutaneous Left Atrial Appendage Occlusion
Where
Austin
Age
18 years and over
People
234
Run by
Texas Cardiac Arrhythmia Research Foundation
See details and how to joinNCT07840365
No phaseTaking people
Digitally Rendered Interventions And Knowledge To Limit Ethanol-Associated Atrial Fibrillation Severity
Where
San Francisco
Age
21 years and over
People
1,000
Run by
University of California, San Francisco
See details and how to joinNCT06995391
No phaseTaking people
Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation
Where
San Francisco
Age
21 years and over
People
100
Run by
University of California, San Francisco
See details and how to joinNCT07220525
Phase 3Taking people
Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR
Where
Oak Lawn
Age
18 years and over
People
153
Run by
Wake Forest University Health Sciences
See details and how to joinNCT06376916
No phaseEnrolling by invitation
KardiaMobile ECG Monitoring Effects on Health Care Utilization and Patient Experience With Atrial Fibrillation
Where
Chicago
Age
18 years to 90 years
People
100
Run by
Northwestern University
See details and how to joinNCT05407415
Phase 4Taking people
Comparing the Safety and Efficacy of Apixaban and Rivaroxaban
Where
Boston, Cleveland, Miami, Minneapolis, Philadelphia, Portland, Salt Lake City, West Los Angeles
Age
22 years and over
People
10,000
Run by
VA Office of Research and Development
See details and how to joinNCT06953726
No phaseTaking people
Real-world Experience of Catheter Ablation for the Treatment of Arrhythmias
Where
Albuquerque, Asheville, Atlanta, Aurora, Austin, Birmingham, Boston, Chandler, Cincinnati, Columbia, Columbus, Dallas, Detroit, Evanston, Golden, Greenville, Haddon Heights, Honolulu, Indianapolis, Iowa City, Jackson, Jacksonville, Janesville, Jonesboro, Lancaster, Lanham, Lansing, Littleton, Los Angeles, Louisville, Lynchburg, Madison, Miami, Midlothian, Mobile, Naperville, Naples, New York, Oklahoma City, Pensacola, Philadelphia, Pittsburgh, Portland, Poughkeepsie, Richmond, Rock Hill, Royal Oak, Saint Matthews, Salt Lake City, Santa Barbara, Sarasota, Savannah, Seattle, Springfield, Syracuse, Tacoma, Tampa, Tucson, Ventura, Walnut Creek, Winchester, Winston-Salem, Winterhaven, York, Ypsilanti
Age
18 years and over
People
20,000 worldwide
Run by
Heart Rhythm Clinical and Research Solutions, LLC
See details and how to joinNCT04088071
No phaseTaking people
The Fourth Left Atrial Appendage Occlusion Study
Where
Albuquerque, Ann Arbor, Asheville, Atlanta, Atlantis, Austin, Baltimore, Birmingham, Boise, Brentwood, Burlington, Canton, Charlottesville, Cincinnati, Cleveland, Coeur d'Alene, Dallas, Detroit, Evanston, Fountain Valley, Hackensack, Hershey, Indianapolis, Jacksonville, Jonesboro, Kansas City, Largo, Lexington, Loma Linda, Los Angeles, Manhasset, Memphis, Milwaukee, New Orleans, New York, Ocala, Pasadena, Philadelphia, Pittsburgh, Providence, Rochester, Rock Island, Sacramento, St Louis, Tacoma, Tampa, The Woodlands, Tulsa, Tyler, West Des Moines, Wilmington
Age
18 years and over
People
4,000 worldwide
Run by
Hamilton Health Sciences Corporation
See details and how to joinNCT05963698
No phaseTaking people
Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic
Where
Cleveland
Age
18 years and over
People
2,000
Run by
The Cleveland Clinic
See details and how to joinNCT00921986
No phaseTaking people
Post-ablation Alcohol Impacts Arrhythmia Recurrence, Quality of Life and Cognition in AF
Where
Austin
Age
18 years to 85 years
People
184
Run by
Texas Cardiac Arrhythmia Research Foundation
See details and how to joinNCT05510167
No phaseTaking people
Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation
Where
Cleveland, Houston
Age
18 years and over
People
400 worldwide
Run by
Oslo University Hospital
See details and how to joinNCT07436299
No phaseTaking people
High-resolution MRI of Atrial Fibrillation Patients Prior to Focal Impulse and Rotor Modulation (FIRM) Ablation
Where
Columbus
Age
18 years and over
People
20
Run by
Ohio State University
See details and how to joinNCT03444337
No phaseNot yet taking people in United States
Shared Decision Making to Address Racial Disparities in Oral Anticoagulation in NVAF
Where
Durham
Age
18 years and over
People
40
Run by
Duke University
See details and how to joinNCT04956978
No phaseTaking people
CellFX® Nanosecond Pulsed Field Ablation (nsPFA)™ Cardiac Surgery Clamp System to Treat Atrial Fibrillation
Where
Ann Arbor, Orlando, St. Helena
Age
18 years to 85 years
People
135
Run by
Pulse Biosciences, Inc.
See details and how to joinNCT06959121
Phase 4Not yet taking people in United States
A Study Of Stellate Ganglion Blockade With Liposomal Bupivacaine In Preventing Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting Surgery
Where
Rochester
Age
40 years and over
People
450
Run by
Mayo Clinic
See details and how to joinNCT07570940
No phaseTaking people
Surveillance Trial of the Apple Watch in Reliable Burden Assessment in Unseen Recurrence of Surgically Treated AF
Where
Cleveland, St Louis
Age
22 years and over
People
75
Run by
The Cleveland Clinic
See details and how to joinNCT07122947
No phaseTaking people
Evaluation of 4D Intracardiac Echocardiography (ICE) During Structural Heart and Electrophysiology Procedures
Where
Cleveland
Age
18 years and over
People
20
Run by
The Cleveland Clinic
See details and how to joinNCT07806890
No phaseNot yet taking people in United States
Empowering Veterans in Research Effectively Using Virtual Engagement Tools
Where
Palo Alto
Age
18 years and over
People
100,000
Run by
VA Office of Research and Development
See details and how to joinNCT07741955