Bipolar disorder trials in United States

In United States 94 Also abroad 235

94 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
Where
Belmont
Age
18 years to 50 years
People
40
Run by
Mclean Hospital
See details and how to joinNCT05837104
Phase 4Taking people
RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)
Where
Rochester
Age
18 years to 65 years
People
120
Run by
Mayo Clinic
See details and how to joinNCT07266545
No phaseTaking people
FOCUS Bipolar: Families Opening Conversations for Understanding Signs
Where
Dallas
Age
7 years and over
People
200
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT07622927
Phase 4Taking people
Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders
Where
Syracuse
Age
16 years to 70 years
People
2,500 worldwide
Run by
Parnassia Groep
See details and how to joinNCT05656469 · EU 2023-509680-25-00
No phaseTaking people
Personalized Mobile Cognitive Behavioral Therapy Application
Where
New York
Age
18 years to 25 years
People
100
Run by
Weill Medical College of Cornell University
See details and how to joinNCT05699525
Phase 4Taking people
CLOZAPINE Response in Biotype-1
Where
Athens, Boston, Chicago, Dallas, Hartford
Age
18 years to 60 years
People
524
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT04580134
Phase 2Taking people
Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder
Where
Ann Arbor
Age
18 years to 60 years
People
50
Run by
Leslie Swanson
See details and how to joinNCT06226025
Phase 2Taking people
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
Where
West Haven
Age
21 years to 65 years
People
30
Run by
Yale University
See details and how to joinNCT05786066
No phaseTaking people
Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study
Where
Rochester
Age
18 years and over
People
200
Run by
Mayo Clinic
See details and how to joinNCT06897670
No phaseTaking people
mHealth Estimate-based Algorithms Signaling Upcoming Recurrence of Episodes in Bipolar Disorders
Where
Minneapolis
Age
18 years and over
People
200
Run by
VA Office of Research and Development
See details and how to joinNCT06204705
No phaseTaking people
Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents
Where
Aurora, Cincinnati, Los Angeles, Pittsburgh
Age
12 years to 21 years
People
80
Run by
University of California, Los Angeles
See details and how to joinNCT06920940
No phaseTaking people
Decoding Emotional Dynamics in Bipolar Disorder
Where
Tulsa
Age
18 years to 65 years
People
72
Run by
Laureate Institute for Brain Research, Inc.
See details and how to joinNCT07221864
No phaseTaking people
Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder
Where
Belmont, Charlestown, Stony Brook
Age
18 years to 45 years
People
100
Run by
Stony Brook University
See details and how to joinNCT06373016
Phase 2Taking people
Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder
Where
Belmont
Age
18 years to 65 years
People
25
Run by
Mclean Hospital
See details and how to joinNCT05457465
No phaseTaking people
Cerebellar Stimulation and Cognitive Control
Where
Iowa City
Age
18 years to 90 years
People
200
Run by
Krystal Parker, PhD
See details and how to joinNCT03217110
Phase 4Taking people
Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder
Where
Rochester
Age
18 years to 65 years
People
100
Run by
Mayo Clinic
See details and how to joinNCT07213466
No phaseTaking people
Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services
Where
Athens, Belmont, Boston, Chicago, Dallas, Hartford
Age
18 years to 40 years
People
320
Run by
Beth Israel Deaconess Medical Center
See details and how to joinNCT06740383
No phaseTaking people
University of Iowa Interventional Psychiatry Service Patient Registry
Where
Iowa City
Age
18 years to 99 years
People
1,000
Run by
Mark Niciu
See details and how to joinNCT04480918
No phaseTaking people
Enhanced Coordinated Specialty Care for Early Psychosis
Where
Belmont, Boston, Cambridge, Worcester
People
350
Run by
Mclean Hospital
See details and how to joinNCT06071858
No phaseTaking people
Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients With Bipolar Depression
Where
Houston
Age
18 years to 50 years
People
45
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT05240352
No phaseTaking people
Greater Houston Area Pediatric Bipolar Registry
Where
Houston
Age
6 years to 17 years
People
1,000
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT06665984
No phaseTaking people
CBT-CP for Veterans With SMI
Where
Baltimore
Age
18 years and over
People
190
Run by
VA Office of Research and Development
See details and how to joinNCT06758414
No phaseEnrolling by invitation
Mindfulness-Based Therapy for Serious Mental Illness
Where
Providence
Age
18 years and over
People
160
Run by
Butler Hospital
See details and how to joinNCT06880796
No phaseTaking people
Children's Bipolar Network Treatment Trial I
Where
Aurora, Los Angeles, Pittsburgh, Richmond
Age
9 years to 19 years
People
80
Run by
University of California, Los Angeles
See details and how to joinNCT05427123
No phaseTaking people
Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device
Where
Philadelphia
Age
18 years to 65 years
People
50
Run by
Gaize
See details and how to joinNCT07389473