Bladder cancer trials in United States

In United States 259 Also abroad 626

259 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
A Study of a Side Effects and Resource Navigation Program for People With Cancer
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Rockville Centre
Age
18 years and over
People
200
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT07646847
Phase 2Taking people
Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer
Where
Astoria, Austin, Bala-Cynwyd, Baltimore, Charleston, Chicago Ridge, Columbus, Dallas, Durham, Germantown, Greenwood, Homewood, Houston, Jeffersonville, Kansas City, Lancaster, Lisle, Little Rock, Morristown, Murrieta, Myrtle Beach, Nashville, New York, North Charleston, Plymouth, Raleigh, Rancho Mirage, San Antonio, San Diego, Springfield, St Louis, Syracuse, The Bronx, Voorhees Township
Age
18 years and over
People
90 worldwide
Run by
Tyra Biosciences, Inc
See details and how to joinNCT06995677 · EU 2025-521277-14-00
Phase 1Taking people
DBC-664 in Adult Patients With Solid Tumors
Where
Denver, East Brunswick, Grand Rapids, Lake Success, Nashville, San Antonio, St Louis
Age
18 years and over
People
210
Run by
Duboce Biopharmaceuticals, Inc.
See details and how to joinNCT07705035
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Baltimore, Buffalo, Chicago, Duarte, Houston, Kissimmee, Nashville, New Haven, New York, Rockville, Saint Louis Park, Saint Paul, Seattle, St Louis
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 1/2Taking people
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Where
Amarillo, Chattanooga, Dallas, Fairfax, Germantown, Los Angeles, Minneapolis, Nashville, New York, Pearland, Salt Lake City, Skokie, Wenatchee, Westbury, White Plains, Whittier
Age
18 years and over
People
680 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06330064 · EU 2023-509632-26-00
Phase 2Not yet taking people in United States
Neoadjuvant Intravesical Nadofaragene Firadenovec With Gemcitabine, Cisplatin and Durvalumab for the Treatment of Muscle Invasive Bladder Cancer, TRIFECTA Trial
Where
Seattle
Age
18 years and over
People
33
Run by
University of Washington
See details and how to joinNCT07332351
No phaseTaking people
Acupuncture and Exercise for EV-Pembro-Induced Peripheral Neuropathy
Where
Boston
Age
18 years and over
People
20
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT07548476
No phaseNot yet taking people in United States
Outcomes for IR and High Risk (HR) Non-muscle Invasive Bladder Cancer (NMIBC) and ctDNA-based Biomarkers for Response and Recurrence in Muscle Invasive Bladder Cancer (MIBC)
Where
Dallas
Age
18 years and over
People
1,400
Run by
Bladder Cancer Advocacy Network
See details and how to joinNCT07893509
Phase 3Taking people
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study
Where
Akron, Alton, Ankeny, Ann Arbor, Antigo, Atlanta, Aurora, Avon, Basking Ridge, Baton Rouge, Battle Creek, Beachwood, Beverly Hills, Billings, Bloomington, Bolivar, Boston, Bozeman, Brighton, Brownstown, Burnsville, Canton, Cape Girardeau, Carbondale, Carterville, Carthage, Cary, Centralia, Chadds Ford, Chapel Hill, Charleston, Chaska, Cheyenne, Chicago, Cleveland, Clinton Township, Clive, Coeur d'Alene, Columbia, Columbus, Commack, Conroe, Coon Rapids, Coral Gables, Creston, Dallas, Danville, Dearborn, Decatur, Deerfield Beach, Denver, Des Moines, Detroit, Dickson City, Dixon, Doral, Durham, Edina, Effingham, Elmhurst, Eureka, Fairbanks, Farmington, Farmington Hills, Fort Smith, Gaffney, Galesburg, Garden City, Grand Rapids, Great Bend, Great Falls, Greenwood, Greer, Harrison, Havre, Hazleton, Hershey, Highlands Ranch, Houston, Irvine, Jackson, Joplin, Kalamazoo, Kalispell, Kansas City, Kewanee, La Jolla, Lawrence, League City, Lebanon, Lee's Summit, Lewes, Lewisburg, Lexington, Lisle, Little Rock, Littleton, Lone Tree, Los Angeles, Macomb, Maple Grove, Maplewood, Mattoon, Mayfield Heights, Mechanicsville, Mentor, Metairie, Miami, Middletown, Midlothian, Millville, Minneapolis, Missoula, Monticello, Montvale, Morgantown, Mount Vernon, Muskegon, Naperville, Nashville, Newark, New Richmond, New York, Niles, North Miami, Norton Shores, Novi, Oak Park, O'Fallon, Oklahoma City, Orange, Orland Park, Osage Beach, Ottawa, Overland Park, Parker, Parkersburg, Pekin, Peoria, Peru, Pittsburg, Plantation, Post Falls, Princeton, Raleigh, Reed City, Rehoboth Beach, Reno, Rhinelander, Richmond, Robbinsdale, Rochester, Rolla, Royal Oak, Sacramento, Saint Cloud, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, Shakopee, Spartanburg, Springfield, Stevens Point, Stillwater, St Louis, Strongsville, Sugar Land, Sullivan, Tarzana, Temple, Topeka, Torrance, Traverse City, Troy, Union, Uniondale, Urbana, Waconia, Washington, Waukee, Wausau, Webster, West Bloomfield, West Des Moines, Westwood, Wheeling, Wichita, Wilkes-Barre, Willmar, Wilmington, Wisconsin Rapids, Woodbury, Wyandotte, Wyoming
Age
18 years and over
People
486 worldwide
Run by
NRG Oncology
See details and how to joinNCT07097142
Phase 1Taking people
Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic
Where
Boston, Fairfax, Irving, Lubbock, Oklahoma City, Orlando
Age
18 years and over
People
285
Run by
Sutro Biopharma, Inc.
See details and how to joinNCT07807345
Phase 1/2Taking people
A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors
Where
Celebration, Fairfax, Hackensack, Nashville, New Hyde Park
Age
18 years and over
People
428 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT07287995
Phase 1/2Taking people
Enfortumab Vedotin, Pembrolizumab and Quemliclustat for the Treatment of Unresectable Locally Advanced and Metastatic Urothelial Cancer
Where
Seattle
Age
18 years and over
People
27
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT07667335
No phaseTaking people
Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2
Where
Chapel Hill, Columbus, Iowa City, Nashville, Seattle, Tampa
Age
18 years and over
People
408
Run by
University of Washington
See details and how to joinNCT07225127
Phase 1Taking people
Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma
Where
Atlanta, Denver, Los Angeles, Milwaukee, Newport, New York, Rochester, San Antonio
Age
18 years and over
People
100
Run by
Nammi Therapeutics Inc
See details and how to joinNCT06582017
Phase 1/2Taking people
GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors
Where
Huntersville, New York
Age
18 years and over
People
317 worldwide
Run by
GI Innovation, Inc.
See details and how to joinNCT04977453
No phaseTaking people
Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers
Where
Duarte
Age
18 years and over
People
224
Run by
City of Hope Medical Center
See details and how to joinNCT05519878
No phaseTaking people
Care of the Urothelial Cancer Patient and Prospective Procurement of Urothelial Cancer Tissue
Where
Bethesda
Age
18 years to 120 years
People
500
Run by
National Cancer Institute (NCI)
See details and how to joinNCT02379429
No phaseTaking people
A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies
Where
Bethesda
Age
18 years and over
People
1,100
Run by
National Cancer Institute (NCI)
See details and how to joinNCT04923178
Phase 2Taking people
Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...
Where
Bethesda
Age
18 years to 120 years
People
60
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06161532
Phase 2Taking people
Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER)
Where
Bethesda
Age
18 years to 120 years
People
45
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06228066
Phase 1/2Taking people
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
Where
Boston, Denver, Houston, Miami, Nashville, San Antonio
Age
18 years and over
People
330
Run by
ModeX Therapeutics, An OPKO Health Company
See details and how to joinNCT06239194
Phase 1/2Taking people
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
Where
Denver, Detroit, New York, Orlando
Age
18 years and over
People
245 worldwide
Run by
BioNTech SE
See details and how to joinNCT07186842 · EU 2025-522613-26-00
No phaseTaking people
Office-Based Ureteroscopy Utilizing a Single Use Digital, Flexible Ureteroscope for Upper Tract Urothelial Carcinoma
Where
Ann Arbor
Age
18 years and over
People
10
Run by
University of Michigan Rogel Cancer Center
See details and how to joinNCT07630155
No phaseTaking people
Bladder Bank (a Prospective Banking Study)
Where
Rochester
Age
18 years and over
People
1,500
Run by
Mayo Clinic
See details and how to joinNCT06109857
Phase 1/2Not yet taking people in United States
Home-Based Outpatient Model for BCG Delivery to Reduce Undue Burden on Patients Undergoing Treatment for Non-Muscle Invasive Bladder Carcinoma
Where
Columbus
Age
18 years and over
People
49
Run by
Ohio State University Comprehensive Cancer Center
See details and how to joinNCT07874347