Bladder cancer trials in United States

In United States 259 Also abroad 626

259 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
Low-grade UTUC Treated With Nadofaragene Firadenovec Administered to Renal Pelvis
Where
Houston, Jacksonville, New York, Philadelphia, Rochester, Santa Monica, Scottsdale
Age
18 years and over
People
20 worldwide
Run by
Ferring Pharmaceuticals
See details and how to joinNCT06668493 · EU 2024-514360-70-00
Phase 1Taking people
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas
Where
Atlanta, Cleveland, Duarte, Durham, Fairfax, Grand Rapids, Houston, Los Angeles, Nashville, New Haven, New York, Philadelphia, San Francisco
Age
18 years and over
People
160
Run by
EvolveImmune United, Inc
See details and how to joinNCT07217171
No phaseTaking people
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Where
Appleton, Aurora, Birmingham, Boston, Broomall, Chandler, Chapel Hill, Cincinnati, Cleveland, Dallas, East Brunswick, Edinburg, Forth Worth, Grand Rapids, Hollywood, Hot Springs, La Jolla, Lakeland, Lewiston, Myrtle Beach, New Orleans, Newport Beach, New York, Philadelphia, Redwood City, Rochester, Rock Hill, Sacramento, Salt Lake City, San Antonio, Shreveport, Toledo, York
Age
18 years and over
People
2,285 worldwide
Run by
Guardant Health, Inc.
See details and how to joinNCT05059444
No phaseNot yet taking people in United States
Feasibility of HISA During TURBT for NMIBC
Where
Charleston
Age
18 years to 89 years
People
40
Run by
CAMC Health System
See details and how to joinNCT07817173
Phase 2/3Taking people
A Study of Ivonescimab in Combination With Enfortumab Vedotin vs Pembrolizumab in Combination With Enfortumab Vedotin in Metastatic Urothelial Carcinoma
Where
Jacksonville, Los Angeles, Nashville, Phoenix, Rochester, Spokane, Washington D.C.
Age
18 years and over
People
800
Run by
Summit Therapeutics
See details and how to joinNCT07815665
No phaseTaking people
A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trial
Where
Seattle
Age
18 years and over
People
128
Run by
University of Washington
See details and how to joinNCT06040762
Phase 2Taking people
Assessment of Decision Tool to Select Women for Gynecologic Sparing Radical Cystectomy
Where
Gainesville
Age
18 years to 99 years
People
127
Run by
University of Florida
See details and how to joinNCT06184516
Phase 1Taking people
A Phase 1/1b Study of IAM1363 in HER2 Cancers
Where
Ann Arbor, Aurora, Austin, Boston, Chicago, Cleveland, Dallas, Detroit, Durham, Fairfax, Grand Rapids, Houston, Kansas City, La Jolla, Lebanon, Los Angeles, Miami, Nashville, New Brunswick, New York, Oklahoma City, Portland, Seattle, St Louis, St. Petersburg, West Valley City
Age
18 years and over
People
383 worldwide
Run by
Iambic Therapeutics, Inc
See details and how to joinNCT06253871
Phase 1Taking people
First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors
Where
Boston, Nashville, New York
Age
18 years and over
People
150 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06644755
Phase 2Taking people
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
Where
Alexandria, Amarillo, Annapolis, Arlington, Atlanta, Austin, Bakersfield, Bala-Cynwyd, Boston, Carmel, Chapel Hill, Charleston, Charlotte, Chicago Ridge, Cincinnati, Cleveland, Clive, Columbus, Dallas, Gahanna, Gainesville, Germantown, Gilbert, Glenview, Greenwood, Hackensack, Hanover, Hershey, Houston, Irvine, Jacksonville, Jeffersonville, Lafayette, Lakewood, Lancaster, Largo, Lisle, Little Rock, Lone Tree, Los Alamitos, Los Angeles, Merrillville, Murrieta, Myrtle Beach, Nashville, New Orleans, New York, North Charleston, Omaha, Orange, Oxford, Philadelphia, Phoenix, Portland, Raleigh, Rochester, Royal Oak, Sacramento, San Antonio, San Diego, Spokane, Springfield, St Louis, Syracuse, Tallahassee, The Bronx, Torrance, Troy, Tucson, Virginia Beach, Wichita, Woodbury
Age
18 years and over
People
325 worldwide
Run by
CG Oncology, Inc.
See details and how to joinNCT06567743
Phase 3Taking people
A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer
Where
Amarillo, Arkansas City, Arlington, Austin, Aventura, Bakersfield, Chandler, Charleston, Charlotte, Charlottesville, Cincinnati, Clive, Columbus, Dallas, Gainesville, Greensboro, Hershey, Hialeah, Homewood, Houston, Margate, Myrtle Beach, New Brunswick, North Charleston, Omaha, Orange, Queen Creek, Rochester, San Antonio, The Bronx, The Woodlands, Tulsa, Washington D.C.
Age
18 years and over
People
70 worldwide
Run by
UroGen Pharma Ltd.
See details and how to joinNCT06774131 · EU 2024-519343-15-00
No phaseTaking people
A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Rockville Centre
Age
18 years and over
People
26
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT05837767
Phase 3Not yet taking people in United States
Effectiveness of Medical and Environmental Interventions to Reduce Cystoscopy Discomfort (CystoDiscomfort)
Where
Birmingham, Chapel Hill, Dallas, White River Junction, Wilmington
Age
18 years and over
People
1,740
Run by
Florian Schroeck
See details and how to joinNCT07795255
Early phase 1Not yet taking people in United States
Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer
Where
Boston, Grand Rapids, New York
Age
18 years and over
People
40
Run by
Lumina Pharmaceuticals Inc
See details and how to joinNCT07781852
Phase 1/2Taking people
Consolidative Therapy After EV + Pembrolizumab in Muscle Invasive Bladder Cancer, REINFORCE Trial
Where
Seattle
Age
18 years and over
People
12
Run by
University of Washington
See details and how to joinNCT07579195
No phaseTaking people
Artificial Intelligence Prediction Tool in Non-muscle Invasive Bladder Cancer (NMIBC)
Where
Dallas, San Antonio
Age
18 years to 99 years
People
600
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT05825950
Phase 2Taking people
Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer
Where
Amarillo, Arlington, Aurora, Austin, Bakersfield, Bloomington, Boston, Cleveland, Denver, Gainesville, Garden City, Homewood, Houston, Jacksonville, Lafayette, Lake Barrington, Lakewood, Little Rock, Lone Tree, Los Angeles, Memphis, Myrtle Beach, Nashville, New York, Orange, Phoenix, Pittsburgh, Plymouth, Queen Creek, Richmond, Rochester, San Antonio, San Diego, Shreveport, Spokane, St Louis, Syracuse, The Bronx, Toledo, Torrance
Age
18 years and over
People
131 worldwide
Run by
Protara Therapeutics
See details and how to joinNCT05951179
No phaseTaking people
Patient-Derived Xenografts to Reduce Cancer Health Disparities
Where
Orange, Sacramento
Age
21 years to 100 years
People
500
Run by
University of California, Davis
See details and how to joinNCT04410302
Phase 1/2Taking people
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
Where
Jacksonville
Age
16 years and over
People
138
Run by
Mayo Clinic
See details and how to joinNCT05269381
Phase 3Taking people
A Study Comparing Standard Treatments in People With Non-Muscle Invasive Bladder Cancer (NMIBC)
Where
Baltimore, Basking Ridge, Commack, East White Plains, Middletown, Montvale, New York, Uniondale
Age
21 years and over
People
125
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT06929286
Phase 2/3Taking people
Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma
Where
Atlanta, Aurora, Austin, Boston, Chapel Hill, Charlottesville, Dallas, Effingham, Fullerton, Germantown, Glendale, Grand Rapids, La Jolla, Largo, Locust Grove, Los Angeles, Madison, Memphis, Monroeville, Myrtle Beach, Nashville, New York, Niles, Norfolk, Orange, Orange City, Peoria, Philadelphia, Portland, Providence, Raleigh, Rochester, San Francisco, Spokane, St Louis, St. Petersburg, Tamarac
Age
18 years and over
People
630 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT07129993
No phaseTaking people
Dosing Physical Activity Among Older Cancer Survivors Who Experience Chronic Pain: a Micro-randomized Trial
Where
Milwaukee
Age
65 years and over
People
50
Run by
Medical College of Wisconsin
See details and how to joinNCT07227077
Phase 1/2Taking people
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
Where
Ann Arbor, Atlanta, Baltimore, Boston, Buffalo, Charlottesville, Chicago, Cincinnati, Grand Rapids, Hackensack, Maywood, New York, Philadelphia, Rochester, San Antonio, Seattle, Tampa, The Bronx
Age
18 years and over
People
300 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT04104776 · EU 2023-508002-20-00
Phase 1Taking people
Study of DCC-2812 in Participants With Advanced Genitourinary Cancers
Where
Ann Arbor, Austin, Boston, Cleveland, Nashville, Philadelphia, San Antonio, St Louis
Age
18 years and over
People
60
Run by
Deciphera Pharmaceuticals, LLC
See details and how to joinNCT06966024
Phase 2Taking people
A Study of T3011 in Patients With BCG-Unresponsive NMIBC or BCG-Exposed, Chemotherapy-Unresponsive NMIBC
Where
Cincinnati, Los Angeles, Middleburg Heights, Myrtle Beach, New Brunswick, Orlando, Pittsburgh, Queen Creek, Tampa
Age
18 years and over
People
160
Run by
ImmVira Pharma Co. Ltd
See details and how to joinNCT06971614