Brain metastases trials in Netherlands

In Netherlands 16 Also abroad 221

16 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer
Where
Amsterdam
Age
18 years and over
People
180 worldwide
Run by
ETOP IBCSG Partners Foundation
See details and how to joinNCT05522660
Phase 2Taking people
Tarlatamab for SCLC Brain Metastases
Where
Amsterdam, Groningen, Maastricht, Rotterdam
Age
18 years and over
People
35
Run by
Maastricht University Medical Center
See details and how to joinNCT07402343 · EU 2025-522162-75-00
Phase 3Taking people
Bevacizumab for the treatment of cerebral RAdiation Induced NecrosiS (BRAINS) study: A multicenter, open-label, randomized clinical trial to assess the clinical efficacy and cost-effectiveness of bevacizumab versus corticosteroids as first-line treatment in patients with symptomatic cerebral radiation necrosis after radiation for high grade glioma or brain metastases
Where
Amsterdam, Leiden, Leidschendam, Maastricht, Nieuwegein, Utrecht
Age
18 years and over
People
408
Run by
Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting
See details and how to join2024-512466-34-00
No phaseTaking people
Pilot IntraOperative Neuronal Electrophysiology in Tumor rElatEd suRgery
Where
Rotterdam
Age
18 years and over
People
20
Run by
Erasmus Medical Center
See details and how to joinNCT06617208
Phase 1Taking people
A Phase 1/1b Study of IAM1363 in HER2 Cancers
Where
Amsterdam
Age
18 years and over
People
383 worldwide
Run by
Iambic Therapeutics, Inc
See details and how to joinNCT06253871
No phaseNot yet taking people in Netherlands
Targeted Pediatric High-Grade Glioma Therapy
Where
Utrecht
Age
12 months to 39 years
People
350 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT05839379
Phase 2Not yet taking people in Netherlands
Study of Olutasidenib and Temozolomide in HGG
Where
Utrecht
Age
12 years to 39 years
People
60 worldwide
Run by
Rigel Pharmaceuticals
See details and how to joinNCT06161974
No phaseTaking people
Novel Ga68-PSMA PET/CT-tracer to Differentiate Between Radiation Necrosis and Tumor Progression in Brain Metastases
Where
Amsterdam
People
100
Run by
The Netherlands Cancer Institute
See details and how to joinNCT07511933
Phase 3Taking people
Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases
Where
Amsterdam, Leiden, Maastricht, The Hague, Utrecht
Age
18 years and over
People
408
Run by
The Netherlands Cancer Institute
See details and how to joinNCT06888817
No phaseTaking people
Value of Screening MRI Brain in Stage IV Non-small Cell Lung Cancer
Where
Groningen, Maastricht, Scheemda
Age
18 years and over
People
100
Run by
University Medical Center Groningen
See details and how to joinNCT05864794
Phase 2Not yet taking people in Netherlands
Boosting Osimertinib Blood Brain Barrier Penetration
Where
Amsterdam, Maastricht, Rotterdam
Age
18 years and over
People
7
Run by
Maastricht University Medical Center
See details and how to joinNCT07485452 · EU 2025-523033-26-00
Phase 2Not yet taking people in Netherlands
Phase II Study of Upfront SRT Plus Ivonescimab/Chemotherapy vs Ivonescimab/Chemotherapy in NSCLC Brain Mets
Where
Maastricht, Rotterdam, Utrecht
Age
18 years and over
People
158 worldwide
Run by
European Organisation for Research and Treatment of Cancer - EORTC
See details and how to joinNCT07234877 · EU 2025-522985-60-00
No phaseEnrolling by invitation
Automated Detection of Brain Metastases on MRI
Where
Amsterdam
Age
18 years and over
People
12
Run by
Robovision BV
See details and how to joinNCT06727032
Phase 2Taking people
Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases
Where
Amsterdam, Groningen, Maastricht
Age
18 years and over
People
25
Run by
Maastricht University Medical Center
See details and how to joinNCT06401824 · EU 2024-514066-40-00
No phaseEnrolling by invitation
Cryoablation of Brain Neoplasm
Where
Rotterdam
Age
18 years to 80 years
People
20
Run by
Erasmus Medical Center
See details and how to joinNCT06753617
No phaseTaking people
Improving Therapeutic Ratio With Hypo Fractionated Stereotactic Radiotherapy for Brain Metastases
Where
Leidschendam
Age
18 years and over
People
130
Run by
Haaglanden Medical Centre
See details and how to joinNCT05346367