Childhood cancers: open trials in Brazil

31 open trials have a site in Brazil. Registry data; only the trial team decides who can take part.

NCT05533775
A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma
Trial Treatment · Phase 1/2 · Hoffmann-La Roche
Hospital Erasto Gaertner, Curitiba · GRAACC - Grupo de Apoio ao Adolescente e a Crianca com Cancer, São Paulo
Registry updated 2026-11-05
NCT04811560
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
Trial Treatment · Phase 1/2 · Janssen Research & Development, LLC
IDOR - Regional Brasilia, Brasília · Liga Norte Riograndense Contra o Cancer, Natal · Ministerio da Saude Instituto Nacional do Cancer, Rio de Janeiro · IDOR - Regional Sao Paulo, São Paulo · Fundacao Antonio Prudente A C Camargo Cancer Center, São Paulo · Fundacao Faculdade de Medicina Instituto do Cancer do Estado de Sao Paulo, São Paulo
Registry updated 2026-11-04
NCT05959720
Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in Brazil
Research · Instituto do Cancer do Estado de São Paulo
Instituto do Câncer do Estado de São Paulo, São Paulo
Registry updated 2026-11-03
NCT06528691
Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors
Trial Treatment · Phase 2 · St. Jude Children's Research Hospital
Hospital de Cancer de Barretos, Barretos · Hospital Santa Marcelina, São Paulo · GRAACC Hospital (Grupo de Apoio ao Adolescente e à Criança com Câncer), São Paulo
Registry updated 2026-11-03
NCT06395103
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
Fundação Pio XII - Hospital de Câncer de Barretos (Site 1264), Barretos · Hospital Erasto Gaertner-CEPEP - Pesquisa Clínica (Site 1268), Curitiba · Hospital de Clinicas de Porto Alegre (Site 1265), Porto Alegre · Fundação Faculdade Regional de Medicina de São José do Rio Preto-Centro Integrado de Pesquisa (Site 1267), São José do Rio Preto
Registry updated 2026-10-30
NCT07101081
GYNGHER - HER2 Expression in Gynecological Malignancies: a Brazilian Cohort
Research · AstraZeneca
São Paulo
Registry updated 2026-10-26
NCT07211958
Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation
Trial Treatment · Phase 3 · Syndax Pharmaceuticals
Barretos · Fortaleza · Jaú · Porto Alegre · São Paulo
Registry updated 2026-10-21
NCT07354074
Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP
Trial Treatment · Phase 2 · Novartis Pharmaceuticals
Barretos · Rio de Janeiro · São Paulo
Registry updated 2026-10-15
NCT06137118
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
Trial Treatment · Phase 1/2 · AstraZeneca
Porto Alegre · São Paulo
Registry updated 2026-10-13
NCT06137144
AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.
Trial Treatment · Phase 1/2 · AstraZeneca
São Paulo
Registry updated 2026-10-13
NCT06941272
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
Fundação Pio XII - Hospital de Câncer de Barretos (Site 3264), Barretos · Hospital de Clinicas de Porto Alegre (Site 3265), Porto Alegre · Fundação Faculdade Regional de Medicina de São José do Rio Preto (Site 3267), São José do Rio Preto
Registry updated 2026-10-06
NCT05797662
A Study of Propranolol to Treat Kaposi Sarcoma
Trial Treatment · Phase 2 · AIDS Malignancy Consortium
Instituto Nacional de Câncer José de Alencar, Rio de Janeiro · Complexo Hospitalar Universitário Professor Edgard Santos, Salvador
Registry updated 2026-10-05
NCT06079671
Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)
Trial Treatment · Phase 3 · AstraZeneca
Barretos · Belo Horizonte · Curitiba · Fortaleza · Goiânia · Ijuí · Natal · Porto Alegre · Porto Velho · Recife · Rio de Janeiro · Salvador · São Paulo · Teresina
Registry updated 2026-09-30
NCT05489887
Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma
Trial Treatment · Phase 2 · Giselle Sholler
GRAACC Hospital, São Paulo
Registry updated 2026-08-12
NCT05697874
International Rare Brain Tumor Registry
Research · Children's National Research Institute
TUCCA - Santa Marcelina, São Paulo
Registry updated 2026-08-07
NCT07070128
Screening Tool Artificial Intelligence-based for Predicting the Genetic Risk of BREAST Cancer
Research · AstraZeneca
Golania · Porto Alegre
Registry updated 2026-07-29
NCT02332668
A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
MSD Brasil, São Paulo
Registry updated 2026-07-06
NCT04877522
Asciminib Roll-over Study
Trial Treatment · Phase 4 · Novartis Pharmaceuticals
Rio de Janeiro · São Paulo
Registry updated 2026-07-06
NCT07109154
DeniLA: Comprehensive Demographics and Clinical Profile of NSCLC Patients: Analyzing Guideline-Concordant Care in First-line Treatment Patterns
Research · AstraZeneca
Recife · Rio de Janeiro · Salvador · São Paulo
Registry updated 2026-05-13
NCT05580562
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)
Trial Treatment · Phase 3 · Jazz Pharmaceuticals
Hcor Research Institute, São Paulo · Hospital do GRAACC, São Paulo · Instituto do Câncer do Estado de São Paulo, São Paulo
Registry updated 2026-04-16
NCT06689956
Outcomes of Low-Risk Endometrial Cancer With Isolated Tumor Cells in the Sentinel Lymph Nodes: A Prospective, Multicenter, Single-Arm Observational Study
Research · Mayo Clinic
AC Camargo Cancer Center, São Paulo
Registry updated 2026-02-19
NCT02848274
ID Of Prognostic Factors In Mycosis Fungoides/Sezary Syndrome
Research · Stanford University
University of Sao Paulo Medical School, São Paulo
Registry updated 2025-10-22
NCT05705570
Clinical Trial Using CAR- T Cells for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies
Trial Treatment · Phase 1 · Nelson Hamerschlak
Hospital Israelita Albert Einstein, São Paulo
Registry updated 2025-09-25
NCT07167329
Real-World Effectiveness and Pharmacogenetics of Belzutifan in VHL Syndrome: The BELIEVE-VHL Trial
Trial Treatment · Phase 2 · José Claudio Casali da Rocha
AC Camargo Cancer Center, São Paulo
Registry updated 2025-09-11
NCT05929976
InterNatIonal CHildhood Leukemia Microbiome/MEtabolome Cohort
Research · Columbia University
Hospital de Cancer Infanto Juvenil de Barretos, Barretos · Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife · Instituto de Tratamento do Câncer Infantil (ITACI), São Paulo
Registry updated 2025-07-22

All Childhood cancers trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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