Chronic kidney disease: open trials in United Kingdom

• NCT06742723

  A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

  Trial Treatment · Phase 3 · AstraZeneca

  Bradford · Bristol · Canterbury · Cardiff · Dundee · Glasgow · Hounslow · London · Salford · Swansea

  Registry updated 2026-11-06

• NCT06234410

  Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation

  Research · University of Edinburgh

  Royal Infirmary of Edinburgh, Edinburgh · Queen Elizabeth Hospital, Glasgow · Imperial College Healthcare NHS Trust, London · University Hospitals Plymouth NHS Trust, Plymouth · Sheffield teaching Hospitals NHS Trust, Sheffield

  Registry updated 2026-11-05

• NCT07241390

  A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)

  Trial Treatment · Phase 3 · Eli Lilly and Company

  FutureMeds - Birmingham, Birmingham · Layton Medical Centre, Blackpool · FutureMeds - Liverpool, Bromborough · Futuremeds-Newcastle, Newcastle · Newquay Health Centre, Newquay · The Adam Practice, Poole · Clifton Medical Centre, Rotherham · Rame Group Practice, Torpoint

  Registry updated 2026-11-04

• NCT06823115

  Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0

  Research · Indiana University

  University Hospital Bristol and Weston, Bristol · Liverpool Women's Hospital, Liverpool · Great Ormond Street Hospital, London · Royal Victoria Infirmary, Newcastle upon Tyne

  Registry updated 2026-10-28

• NCT06593392

  Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus

  Trial Treatment · Phase 2 · Vifor Fresenius Medical Care Renal Pharma

  Royal Hospital for Children Glasgow, Glasgow · Alder Hey Childrens Nhs Foundation Trust, Liverpool

  Registry updated 2026-10-23

• NCT07422532

  A Multi-centre Trial to Assess the Efficacy and Safety of the Omnipod 5 System in People With Type 2 Diabetes Undergoing Haemodialysis

  Trial Treatment · Imperial College London

  Royal Derby Hospital, Derby · Hammersmith Hospital, London · Guys and St Thomas' Hospitals, London · Manchester Royal Infirmary, Manchester

  Registry updated 2026-10-19

• NCT07115953

  Streamlined Denervation With spYral For an Optimized Treatment (SPYRAL SWYFT) in Subjects With Uncontrolled Hypertension

  Trial Treatment · Medtronic Vascular

  Oxford University Hospitals NHS Trust, John Radcliffe Hospital, Oxford

  Registry updated 2026-10-16

• NCT07830719

  Dose-finding Study of YMI024 to Assess Efficacy, Safety, and Tolerability in Adults With Stable Coronary Artery Disease and Elevated hsCRP

  Trial Treatment · Phase 2 · Novartis Pharmaceuticals

  London

  Registry updated 2026-10-15

• NCT04557462

  A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

  Trial Treatment · Phase 3 · Novartis Pharmaceuticals

  Cambridge · Leicester · London · Newcastle upon Tyne · Salford

  Registry updated 2026-10-05

• NCT04522765

  Diurnal BP Patterns in Those at Increased Risk of CVD

  Research · University of Edinburgh

  Royal Infirmary of Edinburgh, Edinburgh

  Registry updated 2026-09-24

• NCT05457283

  A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

  Trial Treatment · Phase 3 · Bayer

  Royal Hospital for Children | Glasgow Clinical Research Facility, Glasgow · Great Ormond Street Hospital for Children | Clinical Research Facility, London · Royal Manchester Children's Hospital | Clinical Research Facility, Manchester · Nottingham Children's Hospital | Renal and Urology Unit, Nottingham

  Registry updated 2026-09-24

• NCT07624305

  A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)

  Trial Treatment · Phase 3 · AstraZeneca

  Aberdeen · Bristol · Cardiff · Dundee · Glasgow · London · Swansea

  Registry updated 2026-09-24

• NCT05485961

  Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

  Trial Treatment · Phase 2/3 · CSL Behring

  University Hospitals Birmingham NHS Foundation Trust - Birmingham Heartlands Hospital (BHH), Birmingham · Bradford Teaching Hospitals NHS Foundation Trust, Bradford · University Hospital Coventry and Warwickshire, Coventry · University Hospitals of Derby and Burton NHS Foundation Trust, Royal Derby Hospital, Derby · Dorset County Hospital NHS Foundation Trust - Dorset County Hospital (DCH), Dorchester · Royal Liverpool University Hospital, Liverpool · William Harvey Research Institute ; Barts Health NHS Trust - The Royal London Hospital, London · Hammersmith Hospital Imperial College Healthcare NHS Trust -Hammersmith Hospital - West London Renal and Transplant Centre, London · King´s College NHS Trust, London · St George's University Hospitals NHS Foundation Trust - St G, London · Altnagelvin Area Hospital, Londonderry · Northern Care Alliance NHS Foundation Trust - Salford Royal NHS Foundation Trust-Salford Care Organisation, Salford · The Shrewsbury and Telford Hospital NHS Trust (SaTH) - Royal Shrewsbury Hospital, Shrewsbury · Royal Stoke University Hospital, Stoke-on-Trent · The Royal Wolverhampton NHS Trust - New Cross Hospital, Wolverhampton

  Registry updated 2026-09-21

• NCT07812571

  Tenofovir Exposures in Advanced Kidney Disease Study

  Research · King's College Hospital NHS Trust

  King's College Hospital, London

  Registry updated 2026-09-10

• NCT07753993

  A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.

  Trial Treatment · Phase 3 · AstraZeneca

  Aberdeen · Cardiff · Corby · Coventry · Dundee · Glasgow · Leicester · Liverpool · London · Metropolitan Borough of Wirral · Northwood · Nottingham · Portsmouth · Shipley · Swansea · Thetford · York

  Registry updated 2026-09-09

• NCT07662135

  A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin

  Trial Treatment · Phase 3 · AstraZeneca

  Blackpool · Glasgow · Hull · Penzance · Sandbach · Thetford · Whitney

  Registry updated 2026-09-02

• NCT03573089

  Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)

  Trial Treatment · The University of Queensland

  NHS Lanarkshire, Airdrie · Wirral University Teaching Hospital NHS Foundation Trust, Birkenhead · University Hospital Birmingham NHS Foundation Trust, Birmingham · Bradford Teaching Hospital NHS Foundation Trust, Bradford · University Hospitals Sussex NHS Foundation Trust, Brighton · West Suffolk Hospital, Bury St Edmunds · Cambridge University Hospitals NHS Foundation Trust, Cambridge · East Kent Hospitals University NHS Foundation Trust, Canterbury · Cardiff and Wales University Local Health Board, Cardiff · North Cumbria Integrated Care NHS Foundation Trust, Carlisle · Epsom and St Helier University Hospitals NHS Trust, Carshalton · Gloucestershire Hospital NHS Foundation Trust, Cheltenham · Portsmouth Hospitals University NHS Trust, Cosham · University Hospitals Coventry & Warwickshire, Coventry · University Hospitals of Derby and Burton, Derby · Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust, Doncaster · Dorset County Hospital NHS Foundation Trust, Dorchester · The Dudley Group Nhs Foundation Trust, Dudley · Royal Devon and Exeter NHS Foundation Trust, Exeter · NHS Greater Glasgow and Clyde, Glasgow · James Paget University Hospitals NHS Foundation Trust, Great Yarmouth · Hull University Teaching Hospital NHS Trust, Hull · Nhs Highland, Inverness · Ipswich Hospital (East Suffolk & North Essex Foundation Trust), Ipswich · NHS Ayrshire and Arran, Kilmarnock · University Hospitals of Leicester NHS Trust, Leicester · Royal Liverpool University Hospitals, Liverpool · University Hospital Aintree, Liverpool · Guy's and St Thomas' NHS Foundation Trust, London · King's College Hospital NHS Foundation Trust, London · St. George's University Hospitals NHS Foundation Trust, London · Manchester University NHS Foundation Trust, Manchester · South Tees Hospitals NHS Foundation Trust, Middlesbrough · The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne · Nottingham University Hospitals NHS Trust, Nottingham · University Hospitals Plymouth NHS Trust, Plymouth · Royal Berkshire NHS Foundation Trust, Reading · Salford Royal NHS Foundation Trust, Salford · Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield · Shrewsbury and Telford Hospital NHS Trust, Shrewsbury · Mid and South Essex NHS Foundation Trust, Southend-on-Sea · East and North Hertfordshire NHS Trust, Stevenage · University Hospital of North Midlands NHS Trust, Stoke-on-Trent · South Tyneside and Sunderland NHS Foundation Trust, Sunderland · The Royal Wolverhampton NHS Trust, Wolverhampton · York and Scarborough Teaching Hospitals NHS Foundation Trust, York

  Registry updated 2026-08-26

• NCT03969329

  A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis

  Trial Treatment · Phase 3 · Amgen

  Royal Hospital for Sick Children, Glasgow · Leeds Teaching Hospitals NHS Trust, Leeds · Great Ormond Street Hospital for Children, London · University Hospital Southampton NHS Foundation Trust, Southampton

  Registry updated 2026-08-21

• NCT05753930

  Imlifidase Prior to Kidney Transplant in Highly Sensitised Children

  Trial Treatment · Phase 2 · Hansa Biopharma AB

  Great Ormond Street Hospital For Children NHS Foundation Trust, London

  Registry updated 2026-08-18

• NCT07768865

  Arterial Stiffness in Children and Young People With Hypertension and Chronic Kidney Disease

  Research · King's College London

  Evelina London Children's Hospital and Guys and St Thomas' NHS Foundation Trust, London

  Registry updated 2026-08-17

• NCT05846581

  Registry of GORE® ACUSEAL Vascular Graft in Dialysis Access

  Research · W.L.Gore & Associates

  North Bristol NHS Trust - Southmead Hospital, Bristol

  Registry updated 2026-08-13

• NCT06830629

  A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

  Trial Treatment · Phase 2 · Maze Therapeutics

  Leicester · London

  Registry updated 2026-07-27

• NCT07613593

  INCLUDE-CKD: INCLUsive Digital carE for Chronic Kidney Disease

  Research · Portsmouth Hospitals NHS Trust

  Portsmouth Hospitals University NHS Trust, Portsmouth

  Registry updated 2026-07-06

• NCT07054684

  Study of BHV-1400 in IgA Nephropathy

  Trial Treatment · Phase 1 · Biohaven Therapeutics Ltd.

  Leicester

  Registry updated 2026-06-23

• NCT02132741

  Optical Coherence Tomography And NEphropathy: The OCTANE Study

  Research · University of Edinburgh

  University of Edinburgh, Edinburgh

  Registry updated 2026-05-13

All Chronic kidney disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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