Chronic kidney disease trials in Germany

In Germany 43 Also abroad 798

43 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease
Where
Berlin
Age
18 years to 65 years
People
112 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07235059
Phase 3Taking people
"AMBITION 2: A research study investigating how well zenagamtide lowers blood sugar and body weight compared to placebo in people with type 2 diabetes and chronic kidney disease treated with once daily basal insulin alone or in combination with metformin, SGLT2i, or both."
Where
Bad Mergentheim, Berlin, Ludwigshafen, Mainz, Münster, Pirna, Pohlheim
Age
18 years and over
People
95 worldwide
Run by
Novo Nordisk A/S
See details and how to join2026-525471-13-00 · EU 2026-525471-13-00
No phaseTaking people
An Observational Study Called FINEROD to Learn More About the Use of the Treatment Finerenone Including How Safe it is and How Well it Works Under Real-world Conditions
Where
Berlin
Age
18 years and over
People
50,000 worldwide
Run by
Bayer
See details and how to joinNCT06278207
Phase 3Taking people
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Where
Bad Homburg, Bamberg, Berlin, Bochum, Brandenburg an der Havel, Brandenburg An Der Havel, Dresden, Essen, Goerlitz, Goettingen, Hanover, Heidelberg, Herne, Karlsburg, Karlsruhe, Landshut, Mainz, Obertshausen, Offenbach Am Main, Potsdam, Reinfeld, Rostock, Rotenburg, Ulm, Wermsdorf, Zwenkau
Age
18 years and over
People
5,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT06742723 · EU 2023-506460-14-00
No phaseTaking people
Impact of Propionic Acid on Regulatory T Cell Function in Children With CKD
Where
Berlin
Age
12 years to 20 years
People
16
Run by
Charite University, Berlin, Germany
See details and how to joinNCT05858437
Phase 3Taking people
A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)
Where
Essen, Essen, Ruhr, Goch, Hamburg, Köln, Oldenburg in Holstein, Stuhr
Age
50 years and over
People
7,140 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07241390 · EU 2025-523123-22-00
Phase 1Not yet taking people in Germany
A study to learn how safe nurandociguat is when taken with sildenafil in men with arterial hypertension.
Where
Berlin, Mannheim
Age
18 years to 64 years
People
36
Run by
Bayer AG
See details and how to join2025-522336-14-00 · EU 2025-522336-14-00
No phaseEnrolling by invitation
Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0
Where
Cologne, Heidelberg, Marburg
Age
0 Minutes to 2 weeks
People
8,000 worldwide
Run by
Indiana University
See details and how to joinNCT06823115
No phaseTaking people
SPYRAL GEMINI Pilot Study
Where
Erlangen, Homburg
Age
18 years to 80 years
People
175 worldwide
Run by
Medtronic Vascular
See details and how to joinNCT06907147
Phase 3Taking people
Phase 3 Clinical Trial With Dapagliflozin in Chronic Kidney Disease in Adolescents and Young Adult Patients
Where
Berlin, Cologne, Frankfurt am Main, Göttingen, Hamburg, Heidelberg, Leipzig, München, Münster
Age
10 years to 39 years
People
102
Run by
University Hospital Goettingen
See details and how to joinNCT05944016 · EU 2023-508502-18-00
No phaseTaking people
Streamlined Denervation With spYral For an Optimized Treatment (SPYRAL SWYFT) in Subjects With Uncontrolled Hypertension
Where
Erlangen, Homburg, Leipzig, Lübeck, Villingen-Schwenningen
Age
18 years and over
People
130 worldwide
Run by
Medtronic Vascular
See details and how to joinNCT07115953
Phase 2Taking people
Dose-finding Study of YMI024 to Assess Efficacy, Safety, and Tolerability in Adults With Stable Coronary Artery Disease and Elevated hsCRP
Where
Berlin, Essen, Freiburg im Breisgau, Gladbeck, Kaiserslautern, Konstanz, Leipzig, Loehne, Ludwigshafen, Mannheim, Pirna, Stuttgart, Ulm
Age
18 years to 80 years
People
180 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07830719 · EU 2026-525974-21-00
Phase 4Taking people
CKD-bioMatch: A biomarker-targeted clinical trial to optimize treatment for patients with chronic kidney disease
Where
Hamburg
Age
18 years and over
People
115 worldwide
Run by
Steno Diabetes Center Copenhagen
See details and how to join2023-507449-27-01 · EU 2023-507449-27-01
Phase 1Not yet taking people in Germany
A Study to Learn About How Safe Nitroglycerin is and How it Affects the Body When Taken Along With Nurandociguat in People With Coronary Artery Disease
Where
Berlin, Bonn, Erfurt, Heidelberg
Age
40 years to 80 years
People
36 worldwide
Run by
Bayer
See details and how to joinNCT07431294 · EU 2025-522335-34-00
Phase 3Taking people
A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy
Where
Aachen, Berlin, Dresden, Essen, Freiburg im Breisgau, Hanover, Kiel, Magdeburg, Mainz, Stuttgart, Tuebingen, Ulm
Age
18 years to 100 years
People
540 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT04557462 · EU 2023-508690-92-00
Phase 3Taking people
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
Where
Berlin, Bonn, Essen, Hamburg, Hanover, Heidelberg, Muenster
Age
1 year to 18 years
People
100 worldwide
Run by
Bayer
See details and how to joinNCT05457283 · EU 2023-504885-50-00
Phase 3Taking people
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
Where
Aachen, Bad Nenndorf, Berlin, Bonn, Brandenburg an der Havel, Braunschweig, Cloppenburg, Essen, Frankfurt am Main, Fulda, Gladbeck, Goslar, Hanover, Heidelberg, Leipzig, Magdeburg, München, Münster, Nuremberg, Obertshausen, Riesa, Rostock, Rotenburg (Wümme), Villingen-Schwenningen, Würzburg
Age
18 years to 99 years
People
2,800 worldwide
Run by
AstraZeneca
See details and how to joinNCT07624305 · EU 2026-526114-90-00
Phase 2Taking people
Efficacy and Safety of SP16 in Preventing Acute Kidney Injury in At-risk Subjects With Chronic Kidney Disease Undergoing Elective Cardiac Surgery Using the Heart-lung-machine
Where
Erlangen
Age
18 years and over
People
120
Run by
University of Erlangen-Nürnberg Medical School
See details and how to joinNCT07661940 · EU 2025-522491-89-00
Phase 2/3Taking people
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
Where
Berlin, Hessen, Kaiserslautern, Kiel, Leipzig, Mainz, Villingen-Schwenningen
Age
18 years and over
People
3,110 worldwide
Run by
CSL Behring
See details and how to joinNCT05485961 · EU 2022-500273-14-00
Phase 3Taking people
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
Where
Aachen, Ahrensburg, Bad Mergentheim, Bad Nenndorf, Bamberg, Berlin, Brandenburg An Der Havel, Brunswick, Chemnitz, Cloppenburg, Dortmund, Dresden, Duesseldorf, Duisburg, Erlangen, Essen, Frankfurt am Main, Freiburg, Fulda, Gladbeck, Goettingen, Goslar, Hamburg, Hanover, Heidelberg, Herne, Kiel, Landshut, Leipzig, Luebeck, Magdeburg, Mannheim, München, Munich, Nuremberg, Reinfeld, Riesa, Rostock, Rotenburg, Stuttgart, Trier, Ulm, Wiesbaden, Wuerzburg
Age
18 years and over
People
7,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT07753993 · EU 2025-523994-41-00
Phase 1Not yet taking people in Germany
A Research Study Looking Into How a Single Dose of the Medicine NNC0537-1482 Moves Through the Body of Participants With Normal or Reduced Kidney Function
Where
Berlin
Age
18 years to 75 years
People
54
Run by
Novo Nordisk A/S
See details and how to joinNCT07808788
No phaseTaking people
Association Between Biomarkers and Kidney Function Decline in Pulmonary Hypertension
Where
Bad Nauheim, Giessen
Age
18 years and over
People
400
Run by
University of Giessen
See details and how to joinNCT06409624
No phaseNot yet taking people in Germany
DKK3 as a Biomarker of Peritoneal Fibrosis in Peritoneal Dialysis Patients
Where
Homburg
Age
18 years and over
People
30
Run by
Universität des Saarlandes
See details and how to joinNCT07806708
Phase 3Taking people
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
Where
Bad Oeynhausen, Berlin, Chemnitz, Duisburg, Erlangen, Frankfurt am Main, Hamburg, Heilbronn, Hohenmölsen, Ludwigshafen, Münster, Nittendorf, Obertshausen, Pirna, St Ingbert, Stuttgart
Age
18 years and over
People
900 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662135 · EU 2025-523940-12-00
Phase 3Taking people
A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis
Where
Cologne, Hamburg, Heidelberg
Age
2 years to 17 years
People
24 worldwide
Run by
Amgen
See details and how to joinNCT03969329 · EU 2023-506471-10-00