Chronic kidney disease trials in United Kingdom

In United Kingdom 40 Also abroad 798

40 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Imlifidase Prior to Kidney Transplant in Highly Sensitised Children
Where
London
Age
1 year to 17 years
People
10 worldwide
Run by
Hansa Biopharma AB
See details and how to joinNCT05753930 · EU 2022-500230-28-00
Phase 3Taking people
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Where
Bradford, Bristol, Canterbury, Cardiff, Dundee, Glasgow, Hounslow, London, Salford, Swansea
Age
18 years and over
People
5,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT06742723 · EU 2023-506460-14-00
No phaseTaking people
Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation
Where
Edinburgh, Glasgow, London, Plymouth, Sheffield
Age
16 years and over
People
332
Run by
University of Edinburgh
See details and how to joinNCT06234410
Phase 3Taking people
A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)
Where
Birmingham, Blackpool, Bromborough, Newcastle, Newquay, Poole, Rotherham, Torpoint
Age
50 years and over
People
7,140 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07241390 · EU 2025-523123-22-00
No phaseEnrolling by invitation
Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0
Where
Bristol, Liverpool, London, Newcastle upon Tyne
Age
0 Minutes to 2 weeks
People
8,000 worldwide
Run by
Indiana University
See details and how to joinNCT06823115
Phase 2Taking people
Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus
Where
Glasgow, Liverpool
Age
12 years to 18 years
People
18 worldwide
Run by
Vifor Fresenius Medical Care Renal Pharma
See details and how to joinNCT06593392 · EU 2023-509909-74-00
No phaseTaking people
A Multi-centre Trial to Assess the Efficacy and Safety of the Omnipod 5 System in People With Type 2 Diabetes Undergoing Haemodialysis
Where
Derby, London, Manchester
Age
18 years and over
People
84
Run by
Imperial College London
See details and how to joinNCT07422532
No phaseTaking people
Streamlined Denervation With spYral For an Optimized Treatment (SPYRAL SWYFT) in Subjects With Uncontrolled Hypertension
Where
Oxford
Age
18 years and over
People
130 worldwide
Run by
Medtronic Vascular
See details and how to joinNCT07115953
Phase 2Taking people
Dose-finding Study of YMI024 to Assess Efficacy, Safety, and Tolerability in Adults With Stable Coronary Artery Disease and Elevated hsCRP
Where
London
Age
18 years to 80 years
People
180 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07830719 · EU 2026-525974-21-00
Phase 3Taking people
A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy
Where
Cambridge, Leicester, London, Newcastle upon Tyne, Salford
Age
18 years to 100 years
People
540 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT04557462 · EU 2023-508690-92-00
No phaseTaking people
Diurnal BP Patterns in Those at Increased Risk of CVD
Where
Edinburgh
Age
18 years to 90 years
People
120
Run by
University of Edinburgh
See details and how to joinNCT04522765
Phase 3Taking people
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
Where
Glasgow, London, Manchester, Nottingham
Age
1 year to 18 years
People
100 worldwide
Run by
Bayer
See details and how to joinNCT05457283 · EU 2023-504885-50-00
Phase 3Taking people
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
Where
Aberdeen, Bristol, Cardiff, Dundee, Glasgow, London, Swansea
Age
18 years to 99 years
People
2,800 worldwide
Run by
AstraZeneca
See details and how to joinNCT07624305 · EU 2026-526114-90-00
Phase 2/3Taking people
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
Where
Birmingham, Bradford, Coventry, Derby, Dorchester, Liverpool, London, Londonderry, Salford, Shrewsbury, Stoke-on-Trent, Wolverhampton
Age
18 years and over
People
3,110 worldwide
Run by
CSL Behring
See details and how to joinNCT05485961 · EU 2022-500273-14-00
No phaseNot yet taking people in United Kingdom
Tenofovir Exposures in Advanced Kidney Disease Study
Where
London
Age
18 years and over
People
50
Run by
King's College Hospital NHS Trust
See details and how to joinNCT07812571
Phase 3Taking people
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
Where
Aberdeen, Cardiff, Corby, Coventry, Dundee, Glasgow, Leicester, Liverpool, London, Metropolitan Borough of Wirral, Northwood, Nottingham, Portsmouth, Shipley, Swansea, Thetford, York
Age
18 years and over
People
7,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT07753993 · EU 2025-523994-41-00
Phase 3Taking people
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
Where
Blackpool, Glasgow, Hull, Penzance, Sandbach, Thetford, Whitney
Age
18 years and over
People
900 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662135 · EU 2025-523940-12-00
No phaseTaking people
Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)
Where
Airdrie, Birkenhead, Birmingham, Bradford, Brighton, Bury St Edmunds, Cambridge, Canterbury, Cardiff, Carlisle, Carshalton, Cheltenham, Cosham, Coventry, Derby, Doncaster, Dorchester, Dudley, Exeter, Glasgow, Great Yarmouth, Hull, Inverness, Ipswich, Kilmarnock, Leicester, Liverpool, London, Manchester, Middlesbrough, Newcastle upon Tyne, Nottingham, Plymouth, Reading, Salford, Sheffield, Shrewsbury, Southend-on-Sea, Stevenage, Stoke-on-Trent, Sunderland, Wolverhampton, York
Age
18 years and over
People
3,600 worldwide
Run by
The University of Queensland
See details and how to joinNCT03573089
Phase 3Taking people
A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis
Where
Glasgow, Leeds, London, Southampton
Age
2 years to 17 years
People
24 worldwide
Run by
Amgen
See details and how to joinNCT03969329 · EU 2023-506471-10-00
No phaseTaking people
Arterial Stiffness in Children and Young People With Hypertension and Chronic Kidney Disease
Where
London
Age
10 years to 25 years
People
200
Run by
King's College London
See details and how to joinNCT07768865
No phaseTaking people
Registry of GORE® ACUSEAL Vascular Graft in Dialysis Access
Where
Bristol
Age
18 years and over
People
72 worldwide
Run by
W.L.Gore & Associates
See details and how to joinNCT05846581
Phase 2Taking people
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
Where
Leicester, London
Age
18 years to 68 years
People
74 worldwide
Run by
Maze Therapeutics
See details and how to joinNCT06830629
No phaseTaking people
INCLUDE-CKD: INCLUsive Digital carE for Chronic Kidney Disease
Where
Portsmouth
Age
18 years and over
People
1,000
Run by
Portsmouth Hospitals NHS Trust
See details and how to joinNCT07613593
Phase 1Taking people
Study of BHV-1400 in IgA Nephropathy
Where
Leicester
Age
18 years to 65 years
People
20 worldwide
Run by
Biohaven Therapeutics Ltd.
See details and how to joinNCT07054684
No phaseTaking people
Optical Coherence Tomography And NEphropathy: The OCTANE Study
Where
Edinburgh
Age
18 years to 80 years
People
150
Run by
University of Edinburgh
See details and how to joinNCT02132741