Chronic myeloid leukaemia trials in Italy

In Italy 19 Also abroad 171

19 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP
Where
Padova, Roma
Age
1 year to 18 years
People
50 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07354074
Phase 4Taking people
Asciminib Roll-over Study
Where
Genoa, Meldola, Milan, Pisa, Rome, Turin
Age
7 years to 100 years
People
347 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT04877522 · EU 2023-507557-16-00
Phase 1/2Taking people
A Clinical Study of MK-4208/TERN-701 in Participants With Chronic Myeloid Leukemia (CML) (MK-4208-003/Tern701-1012/CARDINAL)
Where
Bologna, Milan, Monza
Age
18 years to 64 years
People
330 worldwide
Run by
Terns, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
See details and how to joinNCT06163430 · EU 2023-507677-18-00
Phase 1/2Taking people
Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors
Where
Bologna, Brescia, Genova, Milan, Monza, Naples, Pavia, Rome, Torino
Age
1 year to 17 years
People
70 worldwide
Run by
Incyte Biosciences International Sàrl
See details and how to joinNCT03934372 · EU 2023-509699-41-00
Phase 2/3Taking people
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
Where
Bologna, Florence, Milan, Novara, Ravenna, Rome, Turin
Age
18 years and over
People
316 worldwide
Run by
Taiho Oncology, Inc.
See details and how to joinNCT04256317 · EU 2024-515098-93-00
Phase 4Taking people
Registry and clinical trial comparing standard intensity and reduced intensity treatment in patients with AML or CLL who do not have residual disease.
Where
Bologna, Busto Arsizio, Milan, Modena, Novara, Padova, Perugia, Pescara, Ravenna, Rimini, Rome
Age
18 years and over
People
365 worldwide
Run by
Medizinische Hochschule Hannover
See details and how to join2024-512503-39-00 · EU 2024-512503-39-00
Phase 2Taking people
(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
Where
Bologna, Florence, Salerno, Verona
Age
18 years and over
People
140 worldwide
Run by
Cogent Biosciences, Inc.
See details and how to joinNCT04996875 · EU 2024-511407-42-00
Phase 3Taking people
Study of Olverembatinib (HQP1351) in Patients With CML-CP
Where
Bologna, Candiolo, Catania, Lecce, Meldola, Messina, Milan, Naples, Novara, Padova, Pisa, Rome, Turin, Varese
Age
18 years and over
People
333 worldwide
Run by
Ascentage Pharma Group Inc.
See details and how to joinNCT06423911 · EU 2024-511495-32-00
Phase 2Taking people
Study to evaluate the safety and efficacy of asciminib in pediatric participants with chronic myeloid leukemia.
Where
Padova, Rome
Age
Up to 17 years
People
16 worldwide
Run by
Novartis Pharma AG
See details and how to join2025-522138-29-00 · EU 2025-522138-29-00
No phaseTaking people
A Potential Relationship Between Treatment With Tyrosine Kinase Inhibitors and Erectile Dysfunction in Male Patients With Chronic Myeloid Leukemia
Where
Reggio Emilia
Age
18 years to 75 years
People
350
Run by
Azienda USL Reggio Emilia - IRCCS
See details and how to joinNCT07061145
Phase 2Enrolling by invitation
A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)
Where
Milan
Age
18 years and over
People
332 worldwide
Run by
Taiho Oncology, Inc.
See details and how to joinNCT04093570 · EU 2024-516293-29-01
Phase 1/2Not yet taking people in Italy
A Study to Evaluate S241656 Alone or in Combination in Participants With Selected Myeloid Malignancies
Where
Bologna, Naples, Padova, Pavia, Rozzano
Age
18 years and over
People
64 worldwide
Run by
Servier
See details and how to joinNCT07719348 · EU 2025-525128-88-00
No phaseNot yet taking people in Italy
ENERGIA: Personalized Exercise Program for Fatigue in Patients With Myeloproliferative Neoplasms and Chronic Myeloid Leukemia
Where
Torino
Age
18 years and over
People
25
Run by
Carmen Fava
See details and how to joinNCT07518940
Phase 1Taking people
A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia
Where
Ancona
Age
18 years and over
People
250 worldwide
Run by
Enliven Therapeutics
See details and how to joinNCT05304377 · EU 2023-503335-18-00
No phaseTaking people
Quality of Life and Care Organization of Patients With Chronic Myeloid Leukemia in the Lombardy Hematology Network
Where
Monza
Age
18 years and over
People
2,000
Run by
University of Milano Bicocca
See details and how to joinNCT07165535
Phase 2Taking people
PEARL Study: PotEntial of Asciminib in the eaRly Treatment of CML
Where
Ancona, Bari, Bologna, Brescia, Catania, Florence, Messina, Milan, Naples, Novara, Padova, Palermo, Pavia, Piacenza, Reggio Calabria, Reggio Emilia, Rome, Siena, Turin, Udine, Verona, Vicenza, ULSS3 SERENISSIMA - Ospedale dell'Angelo di Mestre
Age
18 years and over
People
160 worldwide
Run by
Gruppo Italiano Malattie EMatologiche dell'Adulto
See details and how to joinNCT06409936 · EU 2024-512696-12-00
No phaseTaking people
Ponatinib in Chronic Myeloid Leukemia Patients in Chronic Phase
Where
Cagliari, Milan, Naples, Pisa, Roma
Age
18 years and over
People
100
Run by
University of Pisa
See details and how to joinNCT06119269
No phaseTaking people
Interaction Between Gut Microbiota and TKIs in Defining the Clinical Outcomes of Patients With CML
Where
Torino
Age
18 years and over
People
100
Run by
Carmen Fava
See details and how to joinNCT06724536
No phaseTaking people
Italian Treatment Free Remission Registry
Where
Turin
Age
18 years and over
People
800
Run by
University of Turin, Italy
See details and how to joinNCT04769947