Chronic myeloid leukaemia trials in United States

In United States 100 Also abroad 171

100 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML
Where
Birmingham, Boston, Chapel Hill, Dallas, Duarte, Goodyear, Greenville, Houston, Jacksonville, Lake Success, Morristown, Newnan, New Orleans, New York, Phoenix, Rochester, Scottsdale, Tampa, Zion
Age
12 years and over
People
160 worldwide
Run by
Sellas Life Sciences Group
See details and how to joinNCT04588922
Phase 2Taking people
Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide/Tacrolimus/Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell Transplantation
Where
Birmingham, Boston, Columbus
Age
18 years and over
People
124
Run by
Hannah Choe, MD
See details and how to joinNCT07249346
Phase 1Taking people
Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling
Where
Miami
Age
1 day to 21 years
People
65
Run by
Florida International University
See details and how to joinNCT05857969
Phase 2Taking people
Protocol Number: HJKC3-0003. Treatment Free Remission After Asciminib Based Therapy in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation
Where
Buffalo, Detroit, Milwaukee, New York, Salt Lake City
Age
18 years and over
People
51
Run by
Medical College of Wisconsin
See details and how to joinNCT04838041
No phaseTaking people
A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
Where
Akron, Albany, Ann Arbor, Atlanta, Augusta, Austin, Baltimore, Birmingham, Buffalo, Chapel Hill, Chicago, Cleveland, Columbia, Columbus, Dallas, Dayton, Detroit, Fargo, Fort Myers, Fort Worth, Grand Rapids, Greenville, Hackensack, Hollywood, Honolulu, Houston, Jackson, Jacksonville, Kalamazoo, Kansas City, Knoxville, Las Vegas, Madera, Madison, Marshfield, Memphis, Milwaukee, Minneapolis, Nashville, New Haven, Oakland, Oklahoma City, Omaha, Orlando, Pensacola, Philadelphia, Phoenix, Pittsburgh, Portland, Providence, Reno, Sacramento, San Antonio, San Diego, San Francisco, Seattle, Sioux Falls, Spokane, St Louis, Tampa, The Bronx, Wilmington, Winston-Salem
Age
6 years to 39 years
People
330 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT05702645
Phase 2Taking people
Pacritinib vs. Hydroxyurea in Advanced Proliferative Chronic Myelomonocytic Leukemia
Where
Atlanta, Houston, Rochester, Tampa
Age
18 years and over
People
66 worldwide
Run by
Theradex
See details and how to joinNCT07033598
Phase 1Taking people
TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT
Where
Palo Alto
Age
18 years to 80 years
People
50
Run by
Stanford University
See details and how to joinNCT07302776
Phase 2/3Taking people
Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS
Where
Houston
Age
18 years to 70 years
People
324
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT04708054
Phase 1/2Taking people
Pacritinib in CMML
Where
New York
Age
18 years and over
People
26
Run by
Douglas Tremblay
See details and how to joinNCT06159491
Phase 1/2Taking people
Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances
Where
Houston
Age
12 years to 80 years
People
80
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT05092451
Phase 2Enrolling by invitation
A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)
Where
Baltimore, Buffalo, Canton, Charleston, Chicago, Dallas, Fountain Valley, Grand Rapids, Hackensack, Houston, Kennewick, Nashville, Plantation, Portland, Rochester, San Antonio, Seattle
Age
18 years and over
People
332 worldwide
Run by
Taiho Oncology, Inc.
See details and how to joinNCT04093570 · EU 2024-516293-29-01
Phase 2Taking people
Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer
Where
Seattle
Age
18 years and over
People
20
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT07046078
No phaseTaking people
A Real-world Chronic Myelogenous Leukemia (CML) Patient Disease Registry to Describe Patient Experience and Clinical Outcomes Among Patients With CML Receiving Approved First or Second Line Tyrosine Kinase Inhibitor (TKI) Therapy
Where
Baltimore, Birmingham, Canton, Decatur, East Setauket, Kansas City, Pensacola, Salem, Seattle, Sioux Falls, Stamford, Stockton, Syracuse, Tacoma, Temple, Torrance
Age
18 years to 100 years
People
1,000
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07091019
No phaseTaking people
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)
Where
Akron, Amarillo, Ann Arbor, Atlanta, Augusta, Aurora, Baltimore, Beech Grove, Bethesda, Birmingham, Boston, Brandywine, Buffalo, Chapel Hill, Charleston, Charlotte, Charlottesville, Chicago, Cincinnati, Cleveland, Columbus, Dallas, Denver, Detroit, Duarte, Durham, Fort Sam Houston, Fort Worth, Gainesville, Gilbert, Glendale, Grand Rapids, Hackensack, Hershey, Honolulu, Houston, Indianapolis, Iowa City, Jackson, Jacksonville, Kansas City, La Jolla, Lake Sucess, Little Rock, Loma Linda, Los Angeles, Louisville, Lubbock, Madison, Maywood, Memphis, Miami, Milwaukee, Morgantown, Nashville, New Brunswick, New Haven, New Hyde, New Orleans, New York, Oakland, Oklahoma City, Omaha, Orange, Orlando, Park Ridge, Philadelphia, Phoenix, Pittsburgh, Portland, Providence, Richmond, Rochester, Sacramento, Salt Lake City, San Antonio, San Diego, San Francisco, Seattle, Sioux Falls, Stanford, St Louis, Stony Brook, St. Petersburg, Tampa, The Bronx, Tucson, Washington D.C., Westwood, Winston-Salem, Worcester, Zion
People
99,999
Run by
Center for International Blood and Marrow Transplant Research
See details and how to joinNCT01351545
Phase 2Taking people
Allo HSCT Using RIC and PTCy for Hematological Diseases
Where
Minneapolis
Age
Up to 75 years
People
56
Run by
Masonic Cancer Center, University of Minnesota
See details and how to joinNCT05805605
No phaseTaking people
Registry of Older Patients With Cancer
Where
Boone, Chapel Hill, Greenville, Hendersonville, Morehead City, New Bern, Raleigh
Age
65 years and over
People
3,000
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT01137825
Phase 2Taking people
Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning
Where
Duarte
Age
18 years to 80 years
People
35
Run by
City of Hope Medical Center
See details and how to joinNCT06815003
Phase 2Taking people
Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS)
Where
Chicago
Age
18 years to 65 years
People
38
Run by
University of Illinois Chicago
See details and how to joinNCT06802315
Phase 2Taking people
Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders
Where
Minneapolis
Age
Up to 60 years
People
300
Run by
Masonic Cancer Center, University of Minnesota
See details and how to joinNCT03314974
Phase 1/2Taking people
211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia
Where
Seattle
Age
18 years to 75 years
People
75
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT03128034
Phase 1/2Taking people
211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome
Where
Seattle
Age
18 years to 75 years
People
30
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT03670966
Phase 1Taking people
Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap Neoplasms
Where
Rochester
Age
18 years and over
People
25
Run by
Mayo Clinic
See details and how to joinNCT05549661
No phaseTaking people
Impact of Targeted Therapy on Cancer-Related Cognitive Impairment
Where
Rochester
Age
18 years and over
People
400
Run by
University of Rochester NCORP Research Base
See details and how to joinNCT07638007
Phase 2Taking people
Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases
Where
Gainesville
Age
6 months to 39 years
People
20
Run by
University of Florida
See details and how to joinNCT05800210
Early phase 1Taking people
Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant
Where
Rochester
Age
18 years to 75 years
People
24
Run by
Omar Aljitawi
See details and how to joinNCT03964506