Chronic myeloid leukaemia trials in United States

In United States 100 Also abroad 171

100 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies
Where
Seattle
Age
6 months and over
People
60
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT04195633
Phase 2Taking people
A Phase II, Open-Label, Study of Subcutaneous Canakinumab, an Anti-IL-1β Human Monoclonal Antibody, for Patients With Low or Int-1 Risk IPSS/IPSS-R Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia
Where
Houston
Age
18 years and over
People
76
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT04239157
Phase 1Taking people
HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant
Where
Seattle
Age
Up to 80 years
People
24
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT03326921
Phase 1/2Taking people
Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse
Where
Seattle
Age
18 years and over
People
36
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT06928662
No phaseTaking people
MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing
Where
Milwaukee
Age
0 years to 25 years
People
40
Run by
Medical College of Wisconsin
See details and how to joinNCT05794880
No phaseTaking people
Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome
Where
Boston, Brighton, Kalamazoo, Londonderry, Methuen, Milford, Weymouth
Age
18 years and over
People
10,000
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT02269592
Phase 1Taking people
Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.
Where
Boston, Chapel Hill, Chicago, Cincinnati, Columbus, Houston, Salt Lake City
Age
13 years and over
People
100
Run by
Newave Pharmaceutical Inc
See details and how to joinNCT04771572
No phaseTaking people
A Study to Learn About the Study Medicine Bosulif in Adult Patients With Chronic Myeloid Leukemia(CML).
Where
New York
Age
20 years and over
People
600
Run by
Pfizer
See details and how to joinNCT06297161
No phaseTaking people
The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen
Where
Winston-Salem
Age
18 years to 120 years
People
2,000
Run by
Wake Forest University Health Sciences
See details and how to joinNCT01890486
Phase 1Taking people
A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia
Where
Houston, New York, Portland, The Bronx
Age
18 years and over
People
250 worldwide
Run by
Enliven Therapeutics
See details and how to joinNCT05304377 · EU 2023-503335-18-00
Early phase 1Taking people
Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia
Where
Baltimore
Age
18 years to 100 years
People
18
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT07071155
Phase 1Taking people
Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide
Where
Columbus, Westwood
Age
18 years to 65 years
People
38
Run by
University of Kansas Medical Center
See details and how to joinNCT03533816
Phase 2Taking people
A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation
Where
Birmingham, Boston, Chapel Hill, Charlottesville, Detroit, Duarte, Houston, Miami, New York, Palo Alto, Portland, Seattle, Westwood
Age
18 years to 66 years
People
358
Run by
Center for International Blood and Marrow Transplant Research
See details and how to joinNCT06859424
Phase 1Taking people
A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias
Where
Boston, Chicago, Duarte, Houston, Nashville, New York, Palo Alto, Philadelphia, St Louis, Tampa
Age
12 years and over
People
72
Run by
Crossbow Therapeutics, Inc.
See details and how to joinNCT06994676
No phaseTaking people
Impact of Personality on Adherence to Tyrosine Kinase Inhibitor Therapy in Pts w/Chronic Myeloid Leukemia
Where
Orange
Age
18 years and over
People
75
Run by
University of California, Irvine
See details and how to joinNCT06229860
Phase 1Taking people
A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML)
Where
Boston, Houston, Nashville, Portland, Rochester, Stanford, Tampa
Age
18 years and over
People
105
Run by
Solu Therapeutics, Inc
See details and how to joinNCT06950034
Phase 2Taking people
Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML
Where
Sacramento, The Bronx, White Plains
Age
18 years and over
People
91
Run by
Montefiore Medical Center
See details and how to joinNCT05184842
Phase 1Taking people
Selumetinib and Azacitidine in High Risk Chronic Blood Cancers
Where
Chicago
Age
18 years and over
People
18
Run by
University of Chicago
See details and how to joinNCT03326310
Phase 1Taking people
Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL
Where
Atlanta, Augusta, Baltimore, Birmingham, Cleveland, Duarte, Houston, Seattle
Age
18 years and over
People
242 worldwide
Run by
Ascentage Pharma Group Inc.
See details and how to joinNCT04260022
Phase 1Taking people
ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML
Where
Boston, Buffalo, Chicago
Age
18 years and over
People
40
Run by
Marlise Luskin, MD
See details and how to joinNCT03595917
Phase 2Taking people
Two Step Haplo With Radiation Conditioning
Where
Philadephia
Age
18 years and over
People
63
Run by
Thomas Jefferson University
See details and how to joinNCT05031897
Phase 1Taking people
Q702 for the Treatment of Patients With Hematologic Malignancies
Where
Rochester, Scottsdale
Age
18 years and over
People
46
Run by
Mayo Clinic
See details and how to joinNCT06712810
Phase 1/2Taking people
Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Where
Atlanta, Birmingham, Boston, Cleveland, Columbus, Duarte, Durham, Huston, Irvine, La Jolla, Los Angeles, Miami, New Haven, Palo Alto, Sacramento
Age
18 years and over
People
240 worldwide
Run by
Aptose Biosciences Inc.
See details and how to joinNCT03850574 · EU 2023-503244-14-00
Phase 1Taking people
Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)
Where
Boston, Duarte, Minneapolis, New York, Seattle
Age
18 years and over
People
36
Run by
Tr1X, Inc.
See details and how to joinNCT06462365
Phase 1Taking people
Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition
Where
Philadelphia
Age
18 years and over
People
24
Run by
Fox Chase Cancer Center
See details and how to joinNCT06218628