Colorectal cancer trials in Japan

In Japan 47 Also abroad 1930

47 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
Where
Kashiwa
Age
18 years and over
People
430 worldwide
Run by
Pfizer
See details and how to joinNCT04557449 · EU 2024-512120-11-00
Phase 1/2Taking people
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Where
Aichi, Nagoya, Isehara, Kagoshima, Kanagawa, Yokohama, Kashiwa-shi, Kyoto, Osaka, Tokyo, Koto-ku
Age
18 years and over
People
910 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06324357
Phase 3Taking people
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Where
Aichi, Chiba, Ehime, Fukuoka, Gifu, Hiroshima, Hokkaido, Kawasaki, Osaka, Saitama, Sendai, Shizuoka, Tokyo, Toyama, Yokohama
Age
18 years and over
People
900 worldwide
Run by
Summit Therapeutics
See details and how to joinNCT07228832
Phase 3Taking people
A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
Where
Chūōku, Fukuoka, Kitaadachi-gun, Kōtoku, Nagoya, Osaka, Sakai-shi, Sunto, Yokohama
Age
18 years and over
People
1,020 worldwide
Run by
EMD Serono Research & Development Institute, Inc.
See details and how to joinNCT07549412 · EU 2025-524648-37-00
Phase 1Taking people
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
Where
Shizuoka, Tokyo
Age
18 years and over
People
575 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06400472 · EU 2024-511238-11-00
Phase 2Taking people
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Where
Chuo Ku, Kashiwa, Koto-ku, Nagoya, Sakai, Sapporo
Age
18 years and over
People
111 worldwide
Run by
Bayer
See details and how to joinNCT06760819 · EU 2024-517419-62-00
Phase 3Taking people
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
Where
Bunkyo, Chiba, Chūō, Fukuoka, Hidaka, Kashiwa, Kitaadachi-gun, Kita-gun, Koto, Nagoya, Osaka, Sakai, Sapporo, Sendai, Sunto-gun, Yokohama
Age
18 years and over
People
477 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06997497 · EU 2024-517232-22-00
Phase 1Taking people
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Where
Chiba, Kyoto, Osaka
Age
18 years and over
People
421 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07114601 · EU 2025-522367-15-00
Phase 1Taking people
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
Where
Chiba, Kyoto
Age
18 years and over
People
340 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07213791 · EU 2025-521887-37-00
Phase 3Taking people
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Where
Chiba, Chūōku, Kashiwa, Nagoya, Osaka, Shizuoka, Suita, Tokyo
Age
18 years and over
People
1,000 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06662786 · EU 2024-513852-13-00
Phase 3Taking people
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Where
Chiba, Chūōku, Kashiwa, Nagoya, Osaka, Sakai, Shizuoka, Suita, Tokyo
Age
18 years and over
People
700 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06750094 · EU 2024-513853-66-00
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Where
Akashi-shi, Chiba, Chūōku, Fukuoka, Hidaka-shi, Kashiwa-shi, Kawasaki-shi, Kitaadachi-gun, Kita-gun, Kobe, Kōtoku, Kurashiki-shi, Nankoku-shi, Osaka, Shizuoka, Suita-shi, Yokohama
Age
18 years and over
People
700 worldwide
Run by
Incyte Corporation
See details and how to joinNCT07284849 · EU 2025-523735-19-00
Phase 1/2Taking people
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
Where
Kashiwa, Yokohama
Age
18 years and over
People
220 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06428409 · EU 2023-508703-21-00
Phase 1Taking people
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
Where
Hirakata, Koto-Ku
Age
18 years and over
People
404 worldwide
Run by
Astellas Pharma Inc
See details and how to joinNCT07094204 · EU 2025-522082-29-00
Phase 2Taking people
A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer
Where
Chuo-Ku, Kashiwa-shi, Kawasaki-shi, Nagoya, Sendai
Age
18 years and over
People
390 worldwide
Run by
AbbVie
See details and how to joinNCT06820463 · EU 2024-512981-33-00
Phase 1/2Taking people
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Where
Chuo Ku, Kashiwa, Koto-ku, Matsuyama, Nagaizumi-chō, Nagoya, Ōsaka-sayama, Saitama
Age
18 years and over
People
680 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06330064 · EU 2023-509632-26-00
Phase 2/3Taking people
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
Where
Chiba, Chuo Ku, Fukuoka, Hidaka, Ina-machi, Kashiwa, Kobe, Koto-ku, Kurashiki, Matsuyama, Nagaizumi-cho,Sunto-gun, Nagoya, Osaka, Sapporo, Sendai, Suita, Takatsuki, Toyoake, Yamagata, Yokohama
Age
18 years and over
People
990 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07221357 · EU 2025-523224-45-00
No phaseTaking people
TheraSphere Japan Pre-Market Study
Where
Chuo Ku, Kanazawa, Kashihara, Nishinomiya, Sayama
Age
18 years and over
People
51
Run by
Boston Scientific Corporation
See details and how to joinNCT07377487
Phase 1/2Taking people
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
Where
Aichi, Chiba, Hokkaido, Osaka, Tokyo
Age
18 years and over
People
346 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06885034
Phase 3Taking people
A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer
Where
Kashiwa-shi, Kawasaki-shi, Kobe, Koto-ku, Matsuyama, Osaka
Age
18 years and over
People
990 worldwide
Run by
AbbVie
See details and how to joinNCT07525206 · EU 2025-521712-19-00
Phase 1/2Taking people
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Where
Kanagawa, Kyoto, Tokyo
Age
18 years and over
People
554 worldwide
Run by
Institut de Recherches Internationales Servier
See details and how to joinNCT05786924 · EU 2025-523474-16-00
Phase 2Taking people
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
Where
Fukuoka, Gifu, Kashiwa-shi, Nagoya, Osaka, Sendai, Sunto-gun, Yokohama
Age
18 years and over
People
140 worldwide
Run by
AbbVie
See details and how to joinNCT07023289 · EU 2024-518015-19-00
Phase 3Taking people
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Where
Chiba, Fukuoka, Hidaka, Kashiwa, Kitaadachi-Gun, Koto-ku, Nagaizumi-chō, Nagoya, Osaka, Yokohama
Age
18 years and over
People
800 worldwide
Run by
Pfizer
See details and how to joinNCT07222800 · EU 2025-523521-18-00
Phase 2Taking people
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
Where
Chūōku, Kashiwa, Kōtoku, Nagoya, Shinagawa-ku, Suita-shi
Age
18 years to 130 years
People
454 worldwide
Run by
AstraZeneca
See details and how to joinNCT05489211 · EU 2023-509436-26-00
Phase 1/2Taking people
A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors
Where
Chuo Ku, Kashiwa-shi, Koto-ku
Age
18 years and over
People
150 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT07488676