Colorectal cancer trials in Spain

In Spain 148 Also abroad 1942

148 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
Where
Badajoz, Barcelona, Madrid, Pamplona, Santander, Sevilla, Valencia
Age
18 years and over
People
1,394 worldwide
Run by
Exelixis
See details and how to joinNCT05176483 · EU 2023-510061-10-00
Phase 1Taking people
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
Where
Barcelona, Lleida, Madrid, Pozuelo de Alarcón, Valencia
Age
18 years and over
People
392 worldwide
Run by
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
See details and how to joinNCT06625775 · EU 2024-519445-29-00
Phase 1Taking people
A Study of PHN-012 in Patients With Advanced Solid Tumors
Where
Barcelona, Madrid, Valencia
Age
18 years and over
People
165 worldwide
Run by
Pheon Therapeutics
See details and how to joinNCT07127874
Phase 1Taking people
A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors
Where
Barcelona, Madrid, Málaga
Age
18 years and over
People
83 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07277270 · EU 2025-522274-37-00
Phase 2Taking people
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
Where
Barcelona, Córdoba, Madrid, Málaga, Sevilla
Age
18 years to 130 years
People
454 worldwide
Run by
AstraZeneca
See details and how to joinNCT05489211 · EU 2023-509436-26-00
Phase 1/2Taking people
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Where
Barcelona, Madrid, Pamplona, Seville, Valencia, Zaragoza
Age
18 years and over
People
534 worldwide
Run by
Revolution Medicines, Inc.
See details and how to joinNCT06128551
Phase 1Taking people
A PHASE I STUDY OF THE CEACAM5 x CD3 ANTIBODY NILK-2301 IN COLORECTAL CANCER
Where
Barcelona, Madrid
Age
18 years to 64 years
People
12
Run by
NovImmune S.A.
See details and how to join2023-508058-24-01
Phase 4Taking people
Efficacy and tolerability of a simethicone-containing evacuating solution for colorectal cancer screening colonoscopy: a randomized parallel comparative trial. CLEAN+
Where
Barcelona
Age
18 years and over
People
818
Run by
Fundacio De Recerca Clinic Barcelona-Institut D’Investigacions Biomediques August Pi I Sunyer
See details and how to join2025-523748-11-00
Phase 1Taking people
A Phase 1 Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Denikitug (GS-1811), an Afucosylated Anti-CCR8 Monoclonal Antibody, as Monotherapy and in Combination With an Anti–PD-1 Monoclonal Antibody in Adults With Advanced Solid Tumors
Where
Barcelona, Madrid, Pamplona, Pozuelo de Alarcón
Age
18 years and over
People
93 worldwide
Run by
Gilead Sciences Inc.
See details and how to joinNCT05007782 · EU 2022-501684-40-00
Phase 1/2Taking people
A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations
Where
Barcelona, Madrid, Pamplona, Pozuelo de Alarcón
Age
18 years and over
People
265 worldwide
Run by
Blueprint Medicines Corporation
See details and how to joinNCT07629960
Phase 1/2Taking people
A Study to Assess Safety and Efficacy of SOT109 in Patients With Advanced Unresectable or Metastatic Colorectal Cancer
Where
Barcelona
Age
18 years and over
People
100 worldwide
Run by
SOTIO Biotech a.s.
See details and how to joinNCT07693751 · EU 2026-526235-19-00
Phase 1/2Taking people
A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
Where
Barcelona, Madrid
Age
18 years and over
People
47 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07213609
Phase 1Taking people
A phase I open-label, multi-center study to evaluate the safety, tolerability, dosimetry, and preliminary activity of [177Lu]Lu-DFC413 and safety and imaging properties of [68Ga]Ga-NNS309 in patients with solid tumors
Where
Barcelona, L'Hospitalet de Llobregat
Age
18 years and over
People
62 worldwide
Run by
Novartis Pharma AG
See details and how to join2025-521702-18-00
No phaseTaking people
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Where
A Coruña, Barcelona, Girona, Las Palmas de Gran Canaria, Madrid, Málaga, Sabadell, Santiago de Compostela, Valencia
Age
18 years and over
People
2,285 worldwide
Run by
Guardant Health, Inc.
See details and how to joinNCT05059444
Phase 1/2Taking people
Safety of HRX215 in Patients After Minor and Major Liver Resection
Where
Madrid, Valencia
Age
18 years to 75 years
People
80 worldwide
Run by
HepaRegeniX GmbH
See details and how to joinNCT06638502
Phase 2Taking people
A study to evaluate the safety and efficacy of two dose levels of ONO-4578 with Opdivo®, in combination with mFOLFOX6 and bevacizumab versus standard of care in participants with non MSI-H/dMMR, PD-L1 positive advanced colorectal cancer.
Where
Badalona, Barcelona, Córdoba, Madrid, Málaga, Sevilla, Valencia
Age
18 years and over
People
76 worldwide
Run by
Ono Pharmaceutical Co. Ltd.
See details and how to join2024-519590-19-00
Phase 1Taking people
A Phase 1/1b Study of IAM1363 in HER2 Cancers
Where
Barcelona, Madrid, Málaga, Seville, Valencia
Age
18 years and over
People
383 worldwide
Run by
Iambic Therapeutics, Inc
See details and how to joinNCT06253871
Phase 1Taking people
Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
Where
Barcelona, Madrid
Age
12 years to 85 years
People
411 worldwide
Run by
Inhibrx Biosciences, Inc
See details and how to joinNCT03715933 · EU 2023-508139-29-00
Phase 3Taking people
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
Where
Badalona, Barcelona, Burgos, Córdoba, Elche, Granada, L'Hospitalet de Llobregat, Madrid, Málaga, Ourense, Oviedo, Pamplona, Santander, Seville, Valencia, Zaragoza
Age
18 years and over
People
450 worldwide
Run by
Amgen
See details and how to joinNCT06252649
No phaseNot yet taking people in Spain
Optical Diagnosis of Neoplasia Using Artificial Intelligence
Where
Ourense
Age
18 years and over
People
70 worldwide
Run by
Fundacin Biomedica Galicia Sur
See details and how to joinNCT07158203
Phase 1/2Taking people
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
Where
Badalona, Barcelona, Madrid, Málaga, Pamplona
Age
18 years and over
People
1,109 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT04895709
Phase 1/2Taking people
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
Where
Barcelona, Madrid, Valencia
Age
18 years and over
People
366 worldwide
Run by
Marengo Therapeutics, Inc.
See details and how to joinNCT05592626 · EU 2023-505334-10-01
Phase 1Taking people
Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma
Where
Barcelona, Madrid
Age
18 years and over
People
307 worldwide
Run by
Xencor, Inc.
See details and how to joinNCT05433142 · EU 2024-513619-28-00
Phase 3Taking people
Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Subjects With Metastatic Colorectal Cancer With KRAS p.G12C Mutation (CodeBreaK 301)
Where
Badalona, Barcelona, Burgos, Córdoba, Elche, Granada, L'Hospitalet de Llobregat, Madrid, Málaga, Ourense, Oviedo, Pamplona, Santander, Sevilla, Valencia, Zaragoza
Age
18 years to 64 years
People
241 worldwide
Run by
Amgen Inc.
See details and how to join2022-502352-31-00
Phase 1Taking people
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
Where
Barcelona, Madrid
Age
18 years and over
People
434 worldwide
Run by
Amgen
See details and how to joinNCT07094113