Colorectal cancer trials in Spain

In Spain 148 Also abroad 1942

148 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
Where
Barcelona, Madrid
Age
18 years to 100 years
People
162 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06562192
No phaseNot yet taking people in Spain
Personalised Behavioural Intervention in Cancer Screening Programmes
Where
Palma de Mallorca
Age
50 years to 69 years
People
162
Run by
Fundació d'investigació Sanitària de les Illes Balears
See details and how to joinNCT07722442
Phase 3Taking people
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
Where
Alicante, Barcelona, Córdoba, L'Hospitalet de Llobregat, Lleida, Madrid, Málaga, Ourense, Oviedo, Pamplona, San Cristóbal de La Laguna, Santander, Sevilla, Valencia, Zaragoza
Age
18 years and over
People
400 worldwide
Run by
Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT05253651 · EU 2024-514180-25-00
Phase 1Taking people
A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
Where
L'Hospitalet de Llobregat, Madrid
Age
18 years and over
People
914 worldwide
Run by
Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT06131840 · EU 2023-505858-18-00
Phase 1Taking people
A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
Where
Barcelona, Madrid
Age
18 years and over
People
710 worldwide
Run by
Incyte Corporation
See details and how to joinNCT06179160 · EU 2023-507091-47-00
Phase 2Taking people
Randomized Study to Evaluate Melphalan/HDS Treatment Followed by Trifluridine–tipiracil plus Bevacizumab Versus Trifluridine–tipiracil plus Bevacizumab Alone in Metastatic Colorectal Cancer Patients
Where
Barcelona, L'Hospitalet de Llobregat, Madrid
Age
18 years and over
People
35 worldwide
Run by
Delcath Systems Inc.
See details and how to join2024-520356-24-00
Phase 2Taking people
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
Where
Badalona, Barcelona, Córdoba, Madrid, Málaga, Seville, Valencia
Age
18 years and over
People
144 worldwide
Run by
Ono Pharmaceutical Co., Ltd.
See details and how to joinNCT06948448
No phaseEnrolling by invitation
Frequency of Care for Peripherally Inserted Central Vascular Access In the Prevention of Marsi
Where
Badalona
Age
18 years and over
People
150
Run by
Institut Català d'Oncologia
See details and how to joinNCT07697170
Phase 4Taking people
Efficacy and Tolerability of a Simethicone-containing Evacuating Solution for Colorectal Cancer Screening Colonoscopy
Where
Barcelona
Age
50 years to 69 years
People
818
Run by
Fundacion Clinic per a la Recerca Biomédica
See details and how to joinNCT07696793
No phaseTaking people
Stage II/III Colorectal Cancer Recurrence
Where
Barcelona, Madrid
Age
18 years and over
People
400 worldwide
Run by
City of Hope Medical Center
See details and how to joinNCT06314958
No phaseTaking people
Early Onset Colorectal Cancer Detection
Where
Barcelona, Madrid, Salamanca, San Cristóbal de La Laguna
Age
18 years to 50 years
People
400 worldwide
Run by
City of Hope Medical Center
See details and how to joinNCT06342401
No phaseTaking people
Early Detection of Advanced Adenomas and Colorectal Cancer
Where
Barcelona
Age
18 years and over
People
2,000 worldwide
Run by
City of Hope Medical Center
See details and how to joinNCT06342440
Phase 1/2Taking people
A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors
Where
Barcelona, Córdoba, El Palmar, Madrid, Seville, Tarragona, Valencia
Age
18 years and over
People
180 worldwide
Run by
Alentis Therapeutics AG
See details and how to joinNCT07169734 · EU 2025-521441-24-00
Phase 1/2Taking people
A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer
Where
Barcelona, Madrid
Age
18 years and over
People
482 worldwide
Run by
BioNTech SE
See details and how to joinNCT07079631 · EU 2025-521768-36-00
No phaseTaking people
Impact of SMS Messaging on Participation in Colorectal Cancer Screening
Where
Sabadell
Age
50 years to 69 years
People
10,084
Run by
Corporacion Parc Tauli
See details and how to joinNCT07628998
Phase 2Taking people
Bevacizumab plus encorafenib-cetuximab in BRAF-V600E mutated metastatic colorectal cancer, a phase II study with a safety lead-in cohort, the BRAVE trial
Where
A Coruña, Barcelona, Córdoba, L'Hospitalet de Llobregat, Madrid, Málaga, Oviedo, Santander, Valencia, Zaragoza
Age
18 years and over
People
94
Run by
Vall D Hebron Institute Of Oncology
See details and how to join2023-509204-15-00
Phase 3Taking people
CAPRI-3 Phase 3 clinical study to evaluate the use of continuing cetuximab treatment beyond first line progression in molecular selected metastatic colorectal cancer patients
Where
Barcelona, Cartagena, Córdoba, Granada, Madrid, Málaga, Pamplona, Santander
Age
18 years and over
People
360 worldwide
Run by
Gruppo Oncologico Dell'Italia Meridionale
See details and how to join2024-519322-20-00
No phaseTaking people
Mesorectal Microbiome and Metabolome as a Prognostic Factor in Patients With Rectal Cancer
Where
Girona
Age
18 years to 18 years
People
100
Run by
University Hospital of Girona Dr. Josep Trueta
See details and how to joinNCT04804956
Phase 3Taking people
Efficacy of the Use of Neoadjuvant With/Without Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Locally Advanced Colon Cancer
Where
Córdoba
Age
18 years to 75 years
People
1,083
Run by
Maimónides Biomedical Research Institute of Córdoba
See details and how to joinNCT06783491 · EU 2025-520471-29-00
No phaseTaking people
Efficacy and Safety of Transcutaneous Posterior Tibial Nerve Stimulation on Fecal Continence in Patients Undergoing Surgery for Rectal Neoplasia
Where
Manresa
Age
18 years and over
People
84
Run by
Althaia Xarxa Assistencial Universitària de Manresa
See details and how to joinNCT07632196
No phaseTaking people
A Mobile Application to Improve the Quality of Colonoscopy in Colorectal Cancer Screening Program (PrepColon APP)
Where
Valladolid
Age
50 years to 74 years
People
470
Run by
Hospital del Rio Hortega
See details and how to joinNCT06314022
Phase 2Taking people
Single cEll pRofiling PErsistaNce To ImmuNothErapy
Where
Barcelona
Age
18 years and over
People
60
Run by
Vall d'Hebron Institute of Oncology
See details and how to joinNCT06680739
Phase 1/2Taking people
A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies
Where
Badalona, Hortaleza
Age
18 years and over
People
252 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07223047
Phase 1/2Taking people
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
Where
Barcelona, Madrid
Age
12 years and over
People
500 worldwide
Run by
Turning Point Therapeutics, Inc.
See details and how to joinNCT03093116 · EU 2024-512606-25-00
Phase 1/2Taking people
Beamion BCGC-1: A study to find a suitable dose of zongertinib used alone and in combination with other treatments to test whether it helps people with different types of HER2+ cancer that has spread
Where
A Coruña, Barcelona, L'Hospitalet de Llobregat, Madrid, Pamplona, Sevilla, Valencia
Age
18 years and over
People
181 worldwide
Run by
Boehringer Ingelheim International GmbH
See details and how to join2023-509566-38-00