Colorectal cancer trials in Spain

In Spain 148 Also abroad 1942

148 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Liver Transplantation for Non-resectable Colorectal Liver Metastases: Translational Research
Where
Barcelona
Age
18 years to 70 years
People
35
Run by
Hospital Vall d'Hebron
See details and how to joinNCT05398380
Phase 2Taking people
A Study of Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer
Where
Barcelona, Madrid, Oviedo, Valencia
Age
18 years and over
People
120 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06567782
Phase 1Taking people
Phase I open-label, multi-center study to evaluate the safety, tolerability, dosimetry, and preliminary activity of [177Lu]Lu-NNS309 in patients with pancreatic, lung, breast and colorectal cancers.
Where
Barcelona, Madrid
Age
18 years and over
People
76 worldwide
Run by
Novartis Pharma AG
See details and how to join2023-510356-23-00
No phaseTaking people
Effects of UNICLA-A2 Dairy Products on Patients at High-risk of Colorectal Cancer Development
Where
Zaragoza
Age
18 years to 80 years
People
34
Run by
Instituto de Investigación Sanitaria Aragón
See details and how to joinNCT04824053
No phaseTaking people
Multi-scale Spatio-Temporal Analysis of Research Data
Where
Granada
Age
18 years to 90 years
People
15
Run by
Universidad de Granada
See details and how to joinNCT07189312
No phaseTaking people
Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer
Where
Barcelona
Age
18 years to 49 years
People
2,300 worldwide
Run by
San Raffaele University
See details and how to joinNCT05732623
No phaseTaking people
NIMA-Colon Cancer Study
Where
Málaga
Age
18 years to 75 years
People
120
Run by
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
See details and how to joinNCT07534852
No phaseNot yet taking people in Spain
Effectiveness of a Multimodal Outpatient Supervised Physical Activity Program to Improve Tolerance and Efficacy of Chemotherapy in Adults With Breast, Lung and Colon Cancer
Where
Vic
Age
35 years to 65 years
People
70
Run by
University of Vic - Central University of Catalonia
See details and how to joinNCT07502963
No phaseTaking people
Hypofractionated Palliative Radiotherapy in Patients With Advanced Non-operable Rectal Cancer
Where
Terrassa
Age
18 years and over
People
50
Run by
Consorci Sanitari de Terrassa
See details and how to joinNCT03853733
No phaseTaking people
Pain Evaluation Across Robotic and Laparoscopic Surgery for Colorectal Procedures
Where
Madrid
Age
18 years and over
People
80
Run by
Hospital Central de la Defensa Gómez Ulla
See details and how to joinNCT07431892
Phase 2Taking people
Upfront Trastuzumab-Deruxtecan Plus Capecitabine and Bevacizumab for Patients With HER-2 Positive Metastatic Colorectal Cancer.
Where
Barcelona, Granada, Madrid, Santiago de Compostela, Valencia
Age
18 years and over
People
42 worldwide
Run by
Gruppo Oncologico del Nord-Ovest
See details and how to joinNCT07407465 · EU 2024-519479-24-00
Phase 3Taking people
Continuation of Cetuximab Beyond First-Line Progression in Metastatic Colorectal Cancer
Where
Barcelona, Cartagena, Córdoba, Granada, L'Hospitalet de Llobregat, Madrid, Málaga, Pamplona, Santander
Age
18 years and over
People
480 worldwide
Run by
University of Campania Luigi Vanvitelli
See details and how to joinNCT07389265
Phase 1/2Taking people
Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors
Where
Barcelona, Madrid
Age
18 years and over
People
43 worldwide
Run by
One-carbon Therapeutics AB
See details and how to joinNCT07151040 · EU 2024-519639-40-00
Phase 3Taking people
Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
Where
Badajoz, Barakaldo, Barcelona, Córdoba, Donostia, Elche, Granada, Jaén, Las Palmas de Gran Canaria, L'Hospitalet de Llobregat, Madrid, Majadahonda, Málaga, Oviedo, Pamplona, Santander, Sevilla, Valencia, Zaragoza
Age
18 years and over
People
892 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT05855200 · EU 2023-503265-27-00
No phaseEnrolling by invitation
Effectiveness of Health Education as a Nursing Intervention in Improving Quality of Life and Reducing Symptoms of Anxiety and Depression in Ostomy Patients Following Digestive Surgery: A Quasi-Experimental Study.
Where
Santiago de Compostela
Age
18 years and over
People
70
Run by
Hospital Clinico Universitario de Santiago
See details and how to joinNCT07347158
Phase 2Taking people
Phase II study of Durvalumab (MEDI4736) plus Total Neoadjuvant Therapy (TNT) in locally advanced rectal cancer (The DUREC trial)
Where
A Coruña, Barcelona, Elche, L'hospitalet De Llobregat, Madrid, Pamplona, Sabadell, Valencia, Zaragoza
Age
18 years and over
People
60
Run by
Grupo Espanol Multidisciplinar En Cancer Digestivo
See details and how to joinNCT04293419 · EU 2024-515240-24-00
No phaseTaking people
Exploring Participant Preference for Screening Methods and Experience Into Colorectal Cancer Screening Programme
Where
Madrid
Age
50 years to 69 years
People
1,000 worldwide
Run by
ADVANCED MARKER DISCOVERY S.L.
See details and how to joinNCT06696534
No phaseTaking people
Observational Cross-reactivity Study for Colorectal Cancer Diagnosis
Where
Madrid, Málaga, Ourense, Oviedo
Age
18 years and over
People
250
Run by
ADVANCED MARKER DISCOVERY S.L.
See details and how to joinNCT06889844
No phaseTaking people
Development and Validation of a Blood Test for Early Diagnosis of Colorectal Cancer
Where
Barcelona, Bilbao, Donostia / San Sebastian, Madrid, Oviedo, Salamanca, Santander, Zaragoza
Age
18 years and over
People
510
Run by
ADVANCED MARKER DISCOVERY S.L.
See details and how to joinNCT06889883
Phase 2Not yet taking people in Spain
A Study to Characterize Encorafenib Plus Cetuximab as Rechallenge Treatment for BRAF V600E-mutant Metastatic Colorectal Cancer Patients After Previous Therapy With BRAF Inhibitors-based Combinations
Where
Barcelona
Age
18 years and over
People
25
Run by
Vall d'Hebron Institute of Oncology
See details and how to joinNCT07178717 · EU 2023-509564-22-00
Phase 3Taking people
The Sagittarius Trial
Where
Barcelona, Córdoba, L'Hospitalet de Llobregat, Madrid, Pamplona, Sabadell, Santander, Santiago de Compostela, Valencia, Zaragoza
Age
18 years and over
People
700 worldwide
Run by
IFOM ETS - The AIRC Institute of Molecular Oncology
See details and how to joinNCT06490536 · EU 2023-509851-15-00
No phaseNot yet taking people in Spain
Low Powered Colorectal Anastomosis After Rectal Excision (OASIS)
Where
Madrid, Vigo
Age
18 years and over
People
400 worldwide
Run by
Bordeaux Colorectal Institute
See details and how to joinNCT07146334
No phaseTaking people
ALFAOMEGA Master Observational Trial
Where
Barcelona, Valencia
Age
18 years and over
People
3,000 worldwide
Run by
IFOM ETS - The AIRC Institute of Molecular Oncology
See details and how to joinNCT04120935
No phaseTaking people
A Retrospective Protocol Empowering Precision Research in Colorectal Cancer (ALFAOMEGA-RETRÒ)
Where
Barcelona, L'Hospitalet de Llobregat, Valencia
Age
18 years and over
People
500 worldwide
Run by
IFOM ETS - The AIRC Institute of Molecular Oncology
See details and how to joinNCT05101382
Phase 2Not yet taking people in Spain
5-fluorouracil Plus Panitumumab (Anti-EGFR) and Sotorasib (KRAS G12C Inhibitor) in First-line Treatment of Patients Non-eligible for a Doublet/Triplet Chemotherapy With Advanced Unresectab
Where
Barcelona, Córdoba, L'Hospitalet de Llobregat, Madrid, Oviedo, Pamplona, Salamanca, Valencia
Age
18 years and over
People
300 worldwide
Run by
Federation Francophone de Cancerologie Digestive
See details and how to joinNCT07124884 · EU 2024-514030-20-00