COPD trials in Canada

In Canada 34 Also abroad 559

30 of 34 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Inspiratory Muscle Training in Lung Transplant Candidates
Where
Edmonton, Montreal, Toronto, Vancouver
Age
18 years and over
People
90
Run by
University Health Network, Toronto
See details and how to joinNCT06370832
Phase 2Taking people
Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPD
Where
Edmonton
Age
40 years to 80 years
People
160
Run by
University of Alberta
See details and how to joinNCT05061368
Phase 2Taking people
A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
Where
Ajax, Kelowna, Sherbrooke, Trois-Rivières, Windsor
Age
40 years to 75 years
People
606 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07759245 · EU 2026-525480-41-00
Phase 2Taking people
To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment
Where
Ajax, Montreal, Québec, Saint-Charles-Borromée
Age
40 years to 85 years
People
600 worldwide
Run by
Expedition Therapeutics, Inc
See details and how to joinNCT07684820
No phaseTaking people
Lungs on Fire: Wildfire Smoke, Incident Diseases, Susceptible Populations, and Community Values in Canada
Where
Vancouver
Age
19 years to 80 years
People
24
Run by
University of British Columbia
See details and how to joinNCT07536178
Phase 2Taking people
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Where
Ajax, Burlington, Edmonton, Guelph, Hamilton, Québec, Saint-Charles-Borromée, Saskatoon, Sherbrooke, Stoney Creek, Trois-Rivières, Truro, Victoriaville, Winnipeg
Age
40 years and over
People
987 worldwide
Run by
AstraZeneca
See details and how to joinNCT07082738
Phase 3Taking people
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
Where
Kelowna, Longueuil, Montreal, Niagara Falls, Québec, Saint-Charles-Borromée, Trois-Rivières, Victoriaville, West Vancouver, Windsor
Age
40 years to 80 years
People
942 worldwide
Run by
Sanofi
See details and how to joinNCT07190222 · EU 2024-518213-25-00
Phase 2/3Taking people
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Where
Québec, Sherwood Park, Trois-Rivières, Windsor
Age
35 years to 80 years
People
1,156 worldwide
Run by
Pfizer
See details and how to joinNCT07363694 · EU 2024-518587-12-00
Phase 3Enrolling by invitation
A Study to Evaluate the Long-term Safety and Efficacy of Lunsekimig in Adult Participants With Chronic Obstructive Pulmonary Disease (COPD)
Where
Guelph, Saint-Charles-Borromée
Age
40 years to 80 years
People
1,508 worldwide
Run by
Sanofi
See details and how to joinNCT07793409
Phase 4Taking people
A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.
Where
Calgary, London
Age
40 years to 85 years
People
218 worldwide
Run by
Sanofi
See details and how to joinNCT07053423
Phase 3Taking people
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Where
Ajax, Calgary, Guelph, Ottawa, Stoney Creek, Toronto, Vancouver, Waterloo
Age
40 years to 80 years
People
942 worldwide
Run by
Sanofi
See details and how to joinNCT07190209 · EU 2024-518016-39-00
Phase 3Taking people
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation
Where
Ajax, Richmond, Saint-Charles-Borromée, Saskatoon, Sherbrooke, Toronto, Windsor
Age
40 years to 80 years
People
981 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06959095 · EU 2024-520418-22-00
No phaseNot yet taking people in Canada
Indoor Overheating and Physiological Strain in Older Adults With COPD
Where
Ottawa
Age
60 years to 80 years
People
18
Run by
University of Ottawa
See details and how to joinNCT07852910
Phase 3Taking people
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Where
Ajax, Calgary, Guelph, Hamilton, Kelowna, Kingston, Montreal, Québec, Richmond, Saint-Charles-Borromée, Saskatoon, Sherwood Park, Sydney, Thunder Bay, Toronto, Trois-Rivières, Winnipeg
Age
40 years to 80 years
People
5,250 worldwide
Run by
AstraZeneca
See details and how to joinNCT06283966 · EU 2023-507407-59-00
No phaseTaking people
Early Diagnosis and Treatment of Undiagnosed Asthma or COPD: THE UCAP 2 TRIAL
Where
Hamilton, Kingston, Ottawa, Québec, Saskatoon, Toronto
Age
18 years and over
People
420
Run by
Ottawa Hospital Research Institute
See details and how to joinNCT06392776
Phase 3Taking people
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Where
Ajax, Burlington, Calgary, Montreal, Québec, Saint-Charles-Borromée, Saint-Laurent, Saskatoon, Scarborough Village, Toronto, Trois-Rivières, Vancouver, Winchester, Windsor
Age
40 years to 80 years
People
990 worldwide
Run by
AstraZeneca
See details and how to joinNCT06883305 · EU 2024-517458-90-00
Phase 4Taking people
129-Xe MRI Study of Single Triple Therapy Inhaler Effects in COPD Patients With Moderate-severe Dyspnea and/or Poor Health Status With High or Low Risk of Exacerbation
Where
London
Age
50 years to 85 years
People
60
Run by
Western University, Canada
See details and how to joinNCT07192016
Phase 3Taking people
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
Where
Kingston, Windsor
Age
40 years to 75 years
People
1,196 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07177339 · EU 2025-521108-23-00
Phase 3Enrolling by invitation
Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency
Where
Halifax, Toronto
Age
20 years to 72 years
People
290 worldwide
Run by
Grifols Therapeutics LLC
See details and how to joinNCT02796937
No phaseTaking people
CHARM-COPD Program of Care
Where
Toronto
Age
40 years and over
People
100
Run by
University Health Network, Toronto
See details and how to joinNCT06253013
No phaseNot yet taking people in Canada
Evaluating the EAPOC-COPD System
Where
Toronto
Age
18 years and over
People
25
Run by
Women's College Hospital
See details and how to joinNCT06852339
No phaseTaking people
Routine vs On-demand ECMO for Lung Transplantation
Where
Edmonton, Montreal, Toronto, Vancouver
Age
18 years and over
People
218
Run by
Centre hospitalier de l'Université de Montréal (CHUM)
See details and how to joinNCT06615492
No phaseTaking people
My Lung Health Coach-A Virtual COPD Self-management Support Program Integrated Into the Electronic Patient Record
Where
Toronto
Age
40 years to 100 years
People
50
Run by
Women's College Hospital
See details and how to joinNCT07027852
No phaseTaking people
High Flow Nasal Cannula Versus Non-Invasive Ventilation in Exacerbations of Chronic Obstructive Pulmonary Disease
Where
Toronto
Age
40 years and over
People
30
Run by
Unity Health Toronto
See details and how to joinNCT03033251
Phase 4Not yet taking people in Canada
Do Blood Tests Help to Decide Which Patients With Flares of Chronic Obstructive Pulmonary Disease (COPD) Need Antibiotics and Steroids?
Where
Ottawa
People
80
Run by
Ottawa Hospital Research Institute
See details and how to joinNCT06929767