Crohn's disease trials in United States

In United States 125 Also abroad 425

125 trials · From ClinicalTrials.gov, checked 14 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease
Where
Beverly Hills, New York, St Louis
Age
18 years to 80 years
People
60
Run by
Washington University School of Medicine
See details and how to joinNCT06976853
Phase 2Taking people
Amitriptyline for IBS-like Symptoms in Quiescent Crohn's Disease
Where
Ann Arbor
Age
18 years to 65 years
People
100
Run by
University of Michigan
See details and how to joinNCT07556718
Phase 3Taking people
A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease
Where
Colorado Springs, Greenville, Indianapolis, La Jolla, Lexington, Los Angeles, Milwaukee, Naples, New York, Orlando, Rapid City, San Antonio, Seattle, Tampa, Tyler
Age
18 years to 65 years
People
396 worldwide
Run by
Takeda
See details and how to joinNCT06227910 · EU 2023-509391-42-00
Phase 2Taking people
A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)
Where
Glen Burnie, Tyler
Age
18 years to 75 years
People
192 worldwide
Run by
Takeda
See details and how to joinNCT06764615 · EU 2024-518914-18-00
Phase 2Taking people
DB-3Q bmMSC-EVs in Patients With Perianal Fistulizing Crohn's Disease
Where
Aurora, Nashville, New York, Philadelphia, St Louis
Age
18 years to 75 years
People
36
Run by
Direct Biologics, LLC
See details and how to joinNCT06918808
No phaseNot yet taking people in United States
VR Therapies for IBD
Where
Chicago, Los Angeles
Age
18 years and over
People
76
Run by
Brennan Spiegel
See details and how to joinNCT07590518
No phaseTaking people
Study of the Kono-S Anastomosis Versus the Side-to-side Functional End Anastomosis
Where
Boston, Dallas, Houston, New York, Oklahoma City, Seattle
Age
18 years to 90 years
People
600 worldwide
Run by
Weill Medical College of Cornell University
See details and how to joinNCT03256240
Phase 3Taking people
A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Where
Atlanta, Baltimore, Boston, Cleveland, Houston, Indianapolis, Kissimmee, Los Angeles, Minneapolis, Mobile, Morristown, New Hyde Park, Park Ridge, Phoenix, Pittsburgh, Providence, Roanoke, Rochester, San Diego, San Francisco, Stony Brook
Age
2 years to 17 years
People
240 worldwide
Run by
Takeda
See details and how to joinNCT05442567 · EU 2023-509046-36-00
Phase 3Taking people
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)
Where
Atlanta, Baltimore, Boston, Cleveland, Houston, Indianapolis, Kissimmee, Los Angeles, Minneapolis, Morristown, New Hyde Park, Park Ridge, Phoenix, Pittsburgh, Providence, Roanoke, Rochester, San Diego, San Francisco, Stony Brook, Syracuse
Age
2 years to 17 years
People
120 worldwide
Run by
Takeda
See details and how to joinNCT04779320 · EU 2023-509045-13-00
Phase 2/3Taking people
Precise Infliximab Exposure and Pharmacodynamic Control
Where
Cincinnati, Cleveland, Columbus, Indianapolis, Jacksonville, Los Angeles, Milwaukee, Norfolk, Palo Alto, San Diego, Wilmington
Age
6 years to 22 years
People
180
Run by
Children's Hospital Medical Center, Cincinnati
See details and how to joinNCT05660746
Phase 2Taking people
Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease
Where
Austin, Baytown, Bellaire, Brandon, Cedar Park, Clearwater, Colorado Springs, Dallas, Detroit, Evanston, Fairhope, Garland, Harlingen, Harrisburg, Hilliard, Houston, Iowa City, Irvine, Lakeland, Lebanon, Mansfield, Miami, Miami Lakes, Murrieta, Nashville, New Bedford, New Port Richey, Ocala, Orlando, Pittsburgh, Rapid City, Richmond, Roanoke, Salt Lake City, San Antonio, Scottsdale, Seattle, Sun City, Tampa, Temple Terrace, Tyler, Uniontown, Worcester
Age
18 years to 75 years
People
212 worldwide
Run by
Abivax S.A.
See details and how to joinNCT06456593 · EU 2023-508234-34-00
No phaseTaking people
Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)
Where
Seattle
Age
6 years to 21 years
People
200
Run by
Seattle Children's Hospital
See details and how to joinNCT06315179
No phaseEnrolling by invitation
Thermal Measurements of the Gut With a Colonoscope Compatible Thermal Probe
Where
Boston
Age
18 years and over
People
20
Run by
Massachusetts General Hospital
See details and how to joinNCT07352995
No phaseTaking people
COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)
Where
Chapel Hill, Charlotte, Durham, Pittsburgh
Age
1 year to 18 years
People
1,100
Run by
University of North Carolina, Chapel Hill
See details and how to joinNCT07198113
Phase 1Enrolling by invitation
Fecal Microbiome Transplant
Where
Philadelphia
Age
3 years to 21 years
People
250
Run by
Judith Kelsen
See details and how to joinNCT02636517
No phaseTaking people
Therapeutic Endpoint in Pediatric IBD Conditions
Where
Washington D.C.
Age
6 years to 21 years
People
60
Run by
Children's National Research Institute
See details and how to joinNCT06065228
No phaseTaking people
Value of PET/MR Enterography in the Assessment of Crohn's Disease Using a Collagen-binding Radiotracer.
Where
Charlestown
Age
18 years to 99 years
People
25
Run by
Massachusetts General Hospital
See details and how to joinNCT06252493
Phase 2Taking people
A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease
Where
Atlanta, Bellevue, Birmingham, Bridgeton, Cincinnati, Colorado Springs, Cordova, Dallas, Garland, Georgetown, Glenview, Greenville, Gurnee, High Point, Houston, Kansas City, Lafayette, Las Vegas, Liberty, Liberty Township, Little Rock, Littleton, Lubbock, Marrero, Miami, Milwaukee, New York, Orlando, Palmetto Bay, Pensacola, Providence, Raleigh, Rochester, Scottsdale, Shreveport, Silverdale, Snellville, Southlake, Sun City, Tacoma, Tyler, Webster, Ypsilanti
Age
18 years to 80 years
People
140 worldwide
Run by
Mirador Therapeutics, Inc.
See details and how to joinNCT07113522
No phaseTaking people
Impact of Prebiotics in Ulcerative Colitis
Where
Los Angeles
Age
18 years to 85 years
People
70
Run by
University of California, Los Angeles
See details and how to joinNCT06495658
Early phase 1Taking people
Effect of Statins on Crohn's Disease
Where
Stanford
Age
18 years to 80 years
People
20
Run by
Stanford University
See details and how to joinNCT06538649
Phase 1Not yet taking people in United States
Xylitol Use for Decolonization of C. Difficile in Patients With IBD
Where
Boston
Age
18 years and over
People
99
Run by
Brigham and Women's Hospital
See details and how to joinNCT05852587
Phase 1/2Taking people
Stem Cell Transplantation in Crohn's Disease
Where
Los Angeles
Age
13 years to 28 years
People
15
Run by
Cedars-Sinai Medical Center
See details and how to joinNCT04224558
No phaseTaking people
A Pilot Study to Assess the Safety, Tolerability, and Efficacy of Virtual Reality for the Treatment of Abdominal Pain in Quiescent Crohn's Disease
Where
Jacksonville
Age
18 years to 70 years
People
15
Run by
Mayo Clinic
See details and how to joinNCT06647615
Early phase 1Taking people
68Ga-FAPI-46 PET/CT for Assessing Small Bowel Fibrostenosis in Crohn's Disease
Where
Rochester
Age
18 years and over
People
45
Run by
Mayo Clinic
See details and how to joinNCT07273188
No phaseNot yet taking people in United States
ACT for Veterans With IBD and Mental Health Challenges
Where
Houston
Age
18 years and over
People
50
Run by
VA Office of Research and Development
See details and how to joinNCT07397195