Depression trials in Canada

In Canada 75 Also abroad 664

75 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults
Where
Toronto
Age
60 years and over
People
28
Run by
Rotman Research Institute at Baycrest
See details and how to joinNCT03665831
No phaseTaking people
Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation
Where
Winnipeg
Age
6 years to 24 years
People
160
Run by
University of Manitoba
See details and how to joinNCT06763081
No phaseTaking people
The Impact of Coach-guided Risk Communication on the Risk of Major Depression
Where
Halifax
Age
18 years to 65 years
People
1,000
Run by
Dalhousie University
See details and how to joinNCT06619366
No phaseTaking people
rTMS for Youth Inpatients With Depression
Where
Toronto
Age
14 years to 19 years
People
30
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT07140575
Phase 1Taking people
Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for Refractory Anorexia Nervosa With Comorbid Obsessive Compulsive Disorder or Major Depressive Disorder
Where
Toronto
Age
18 years to 65 years
People
10
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT07113665
No phaseTaking people
Focused Ultrasound Neuromodulation in Patients With Treatment-Resistant Depression
Where
Toronto
Age
18 years to 65 years
People
20
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT07094789
No phaseTaking people
Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar Depression
Where
Toronto
Age
18 years to 65 years
People
10
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT07108257
Phase 1Taking people
Theta-Burst Stimulation to Treat Depression
Where
Toronto
Age
18 years to 50 years
People
84
Run by
Centre for Addiction and Mental Health
See details and how to joinNCT07033780
No phaseTaking people
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
Where
Montreal
Age
9 years to 25 years
People
560
Run by
Douglas Mental Health University Institute
See details and how to joinNCT06978452
No phaseTaking people
Skills for Wellness
Where
Halifax
Age
9 years to 21 years
People
360
Run by
Nova Scotia Health Authority
See details and how to joinNCT01980147
Phase 4Taking people
Personalized Indications for CBT and Antidepressants in Treating Depression
Where
Halifax
Age
18 years and over
People
80
Run by
Nova Scotia Health Authority
See details and how to joinNCT02752542
No phaseTaking people
Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use
Where
Halifax
Age
12 years to 21 years
People
120
Run by
Nova Scotia Health Authority
See details and how to joinNCT03601026
No phaseTaking people
Physical Activity Program for TRD
Where
Toronto
Age
18 years to 65 years
People
30
Run by
Unity Health Toronto
See details and how to joinNCT06404320
No phaseTaking people
Temporal Interference and Depression
Where
Toronto
Age
18 years to 65 years
People
30
Run by
Unity Health Toronto
See details and how to joinNCT05295888
Phase 1Taking people
qEEG Brain Signature of Depression & Neuromodulation-induced Recovery
Where
North York, Toronto
Age
18 years to 80 years
People
100
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT06719427
No phaseTaking people
Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression
Where
Toronto
Age
18 years to 55 years
People
52
Run by
Centre for Addiction and Mental Health
See details and how to joinNCT04935619
No phaseNot yet taking people in Canada
Intermittent Fasting for Inflammation and Depression in Spinal Cord Injury
Where
London
Age
18 years and over
People
32
Run by
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
See details and how to joinNCT06807528
Phase 4Taking people
ECT with Ketamine Anesthesia Vs High Intensity Ketamine with ECT Rescue for Treatment-Resistant Depression
Where
Saskatoon
Age
18 years and over
People
62
Run by
University of Saskatchewan
See details and how to joinNCT03272698
No phaseNot yet taking people in Canada
Neurocardiac Predictors of Treatment Response to RTMS in Depression
Where
Vancouver
Age
19 years to 65 years
People
110
Run by
University of British Columbia
See details and how to joinNCT05139862
No phaseTaking people
The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression
Where
Toronto
Age
18 years to 65 years
People
50
Run by
Unity Health Toronto
See details and how to joinNCT06163625
No phaseTaking people
Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study
Where
Toronto
Age
18 years and over
People
200
Run by
Unity Health Toronto
See details and how to joinNCT06732089
No phaseTaking people
Light and Ion Maintenance In Treatment for Depression (LIMIT-D): Feasibility Study
Where
Vancouver
Age
19 years to 65 years
People
100
Run by
University of British Columbia
See details and how to joinNCT05423275
No phaseTaking people
Interleaved TMS-fMRI in Ultra-treatment Resistant Depression
Where
Toronto
Age
20 years to 65 years
People
88
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT05813093
No phaseTaking people
Risk and Resiliency Factors in the RCMP: A Prospective Investigation
Where
Regina
Age
19 years to 57 years
People
960
Run by
University of Regina
See details and how to joinNCT05527509
No phaseTaking people
E-field Guided iTBS for Treatment Resistant Depression
Where
Toronto
Age
18 years to 65 years
People
110
Run by
Centre for Addiction and Mental Health
See details and how to joinNCT05583747