Dermatomyositis and polymyositis (myositis) trials in United States

In United States 45 Also abroad 124

45 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Where
Arlington, Bellaire, Charleston, Charlotte, Chula Vista, Covina, Gainesville, Great Falls, Hixson, Iowa City, Irving, Jackson, Jupiter, Katy, Los Alamitos, Los Angeles, Mesquite, Miami, Norcross, Phoenix, Plantation, Red Oak, Roanoke, Santa Ana, Statesville, Tucson, Tuscaloosa, Tustin, Willowbrook, Woodland
Age
18 years and over
People
90 worldwide
Run by
Artiva Biotherapeutics, Inc.
See details and how to joinNCT06991114 · EU 2025-520461-41-00
Phase 1Not yet taking people in United States
BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune Disease
Where
Boston
Age
16 years to 75 years
People
94
Run by
Luminary Therapeutics
See details and how to joinNCT07729995
Phase 1/2Taking people
Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders
Where
Cincinnati, St Louis, Washington D.C.
Age
12 years and over
People
50
Run by
Cartesian Therapeutics
See details and how to joinNCT07089121
Phase 1Taking people
Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)
Where
Amarillo, Austin, Baltimore, Chapel Hill, Columbus, Houston, Lake Success, New York, Orange, Philadelphia, Portland
Age
18 years to 85 years
People
144 worldwide
Run by
Chugai Pharmaceutical
See details and how to joinNCT06371417 · EU 2023-507692-21-00
Phase 1Taking people
A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
Where
Boston, Durham
Age
18 years and over
People
125 worldwide
Run by
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
See details and how to joinNCT07115745 · EU 2024-517681-41-00
Phase 2Taking people
Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty
Where
New York
Age
18 years and over
People
80
Run by
NYU Langone Health
See details and how to joinNCT07138898
No phaseNot yet taking people in United States
Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress
Where
Durham
Age
13 years to 22 years
People
25
Run by
Duke University
See details and how to joinNCT06999109
Phase 1Taking people
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
Where
Beverly Hills, Cleveland, Durham, Fullerton, Gainesville, Irvine, Los Angeles, Louisville, Memphis, Miami, Minneapolis, New York, Oklahoma City, Omaha, Philadelphia, San Francisco
Age
12 years to 70 years
People
244 worldwide
Run by
Fate Therapeutics
See details and how to joinNCT06308978
Phase 2Taking people
Intralesional Injection of STS in Treatment of Calcinosis
Where
Pittsburgh
Age
18 years and over
People
20
Run by
Robyn T. Domsic, MD, MPH
See details and how to joinNCT06672822
Phase 2/3Taking people
Safety and Efficacy of ULSC on Disease Severity and Steroid Tapering in Participants With Dermatomyositis/ Polymyositis (DM/PM), Also Known as Idiopathic Inflammatory Myopathy (IIM)
Where
Gainesville, Miami
Age
18 years and over
People
40
Run by
Restem, LLC.
See details and how to joinNCT07160205
No phaseTaking people
Muscle Health Measurements Using Electrical Impedance Myography
Where
Boston
Age
18 years to 89 years
People
150
Run by
Beth Israel Deaconess Medical Center
See details and how to joinNCT07502989
No phaseTaking people
Clinical Responsiveness of Dermatomyositis Using Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI)
Where
Philadelphia
Age
18 years and over
People
300
Run by
University of Pennsylvania
See details and how to joinNCT02945345
Phase 1Enrolling by invitation
A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease
Where
Buffalo, Redwood City
Age
18 years to 80 years
People
180
Run by
Adicet Therapeutics
See details and how to joinNCT06375993
No phaseTaking people
Rheumatology Patient Registry and Biorepository
Where
New Haven
Age
18 years to 99 years
People
5,000
Run by
Yale University
See details and how to joinNCT04402086
Phase 2/3Taking people
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Where
Denver
Age
18 years and over
People
70 worldwide
Run by
Kyverna Therapeutics
See details and how to joinNCT07403188 · EU 2024-511198-31-00
No phaseTaking people
MIHRA - Patient-Rooted Insights for Shaping Myositis Science (PRISMS)
Where
New Orleans
Age
7 years and over
People
700
Run by
Myositis International Health & Research Collaborative Alliance Foundation
See details and how to joinNCT07374107
Early phase 1Taking people
Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Patients With Sporadic Inclusion Body Myositis
Where
Austin
Age
45 years to 75 years
People
10
Run by
Austin Neuromuscular Center
See details and how to joinNCT06479863
Phase 1Taking people
Study of KYV-101 Anti-CD19 CAR T Therapy in Adult Dermatomyositis
Where
Palo Alto, Stanford
Age
25 years to 72 years
People
21
Run by
Stanford University
See details and how to joinNCT06298019
No phaseTaking people
Rheumatology Diet Study
Where
Orlando
Age
18 years to 65 years
People
500
Run by
University of Central Florida
See details and how to joinNCT06339957
Phase 2Not yet taking people in United States
Evaluation of Patients With Refractory Dermatomyositis Using [18F] FAPI-74 PET/MRI Imaging
Where
Stanford
Age
18 years and over
People
21
Run by
Farshad Moradi
See details and how to joinNCT06568783