Down syndrome trials in Spain

In Spain 11 Also abroad 94

11 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Sleep and body temperature as markers of progression of Alzheimer's disease in Down syndrome.
Where
Barcelona
Age
18 years to 64 years
People
60
Run by
Fundacio Institut De Recerca De L Hospital De La Santa Creu I Sant Pau
See details and how to join2023-506609-21-00
Phase 2Taking people
A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)
Where
Barcelona, Dos Hermanas, Madrid, Málaga, Pamplona, Valencia
Age
40 years to 55 years
People
58 worldwide
Run by
Alnylam Pharmaceuticals
See details and how to joinNCT07636811 · EU 2025-523390-42-00
Phase 1/2Taking people
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
Where
Barcelona, Granada, Madrid, Santander, Valencia
Age
35 years to 85 years
People
304 worldwide
Run by
AC Immune SA
See details and how to joinNCT05462106 · EU 2022-500069-29-00
No phaseEnrolling by invitation
Immersive Virtual Reality Program in Down Syndrome
Where
Pontevedra
Age
16 years to 50 years
People
20
Run by
University of Vigo
See details and how to joinNCT07668908
No phaseTaking people
Trial-Ready Cohort-Down Syndrome (TRC-DS)
Where
Barcelona
Age
25 years to 55 years
People
550 worldwide
Run by
University of Southern California
See details and how to joinNCT04165109
Phase 2Taking people
AEF0217 in Participants With Down Syndrome
Where
Barcelona, Madrid
Age
16 years to 32 years
People
188 worldwide
Run by
Aelis Farma
See details and how to joinNCT07334912 · EU 2025-521013-10-00
No phaseEnrolling by invitation
Qualitative Effects of AEF0217 in Down Syndrome People
Where
Barcelona
People
28
Run by
Aelis Farma
See details and how to joinNCT07413224
Phase 3Taking people
LEvetiracetam to Prevent Seizures in Symptomatic Alzheimer's Disease in Adults With Down Syndrome
Where
Barcelona, Donostia, Granada, Madrid, Santander
Age
40 years and over
People
120
Run by
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
See details and how to joinNCT07234695 · EU 2024-516148-24-00
No phaseTaking people
Using Technologies to Promote HEalthy Lifestyles in Adolescents With Intellectual Disabilities
Where
Seville
Age
4 years to 30 years
People
60
Run by
University of Seville
See details and how to joinNCT07101523
Phase 2Taking people
LONGITUDINAL STUDY OF THE POSITRON EMISSION TOMOGRAPHY (PET) TRACER FOR TAU 18F-PI-2620 IN INDIVIDUALS WITH DOWN SYNDROME
Where
Barcelona
Age
18 years and over
People
80
Run by
Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau
See details and how to join2024-515574-27-00
No phaseEnrolling by invitation
Relationship Between Eating Patterns, Body Composition and the Detection of Fatty Liver in Children and Adolescents With Trisomy 21: LiverTy Project
Where
Madrid
Age
5 years to 22 years
People
34
Run by
IMDEA Food
See details and how to joinNCT06888570