Epidermolysis bullosa trials in United States

In United States 19 Also abroad 30

19 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Early phase 1Enrolling by invitation
Thera-Clean® Microbubbles System in Patients With Skin Diseases
Where
Chicago
Age
2 years and over
People
20
Run by
Northwestern University
See details and how to joinNCT07050810
Phase 2Not yet taking people in United States
Filsuvez in Moderate-to-Severe Epidermolysis Bullosa Simplex
Where
Palo Alto
Age
6 months and over
People
10
Run by
Stanford University
See details and how to joinNCT07756138
Phase 2Taking people
A Phase 2 Study of TCP-25 Gel in Patients With Epidermolysis Bullosa, STEP-study
Where
Cincinnati
Age
4 years and over
People
32 worldwide
Run by
Xinnate AB
See details and how to joinNCT06594393
Phase 3Taking people
Efficacy and Safety Study to Evaluate SD-101 in Epidermolysis Bullosa
Where
Charleston, Philadelphia, Rancho Santa Margarita, Redwood City
Age
28 days to 12 years
People
80
Run by
Paradigm Therapeutics
See details and how to joinNCT07482787
No phaseNot yet taking people in United States
A Study to Assess the Incidence of Skin Cancers in Patients With Epidermolysis Bullosa Receiving Filsuvez
Where
Aurora, Charleston, Cincinnati, Gainesville, Palo Alto, Philadelphia
People
170 worldwide
Run by
Chiesi Farmaceutici S.p.A.
See details and how to joinNCT06423573
No phaseTaking people
Impact of Body Positioning on EndoFLIP Measurements: A Comparative Study of Supine and Left Lateral Decubitus Positions
Where
Baltimore
Age
5 years to 21 years
People
25
Run by
Johns Hopkins University
See details and how to joinNCT07780981
Phase 2Taking people
A Phase II, Placebo Controlled, Clinical Trial of Topical TolaSure Targeting Aggregated Mutant Keratin in Epidermolysis Bullosa Simplex
Where
Chicago, Palo Alto
Age
2 years and over
People
40
Run by
BioMendics, LLC
See details and how to joinNCT07027345
No phaseEnrolling by invitation
A Long-Term Extension Study for Participants Previously Treated With EB-101 for the Treatment of RDEB
Where
Redwood City, Worcester
Age
6 years and over
People
22
Run by
Abeona Therapeutics, Inc
See details and how to joinNCT05708677
No phaseTaking people
A Long-Term Safety Follow-up Registry for Patients Who Received Treatment With Prademagene Zamikeracel for Recessive Dystrophic Epidermolysis Bullosa (RDEB) in the Post-Marketing Setting
Where
Aurora, Chicago, Galveston, Palo Alto
People
250
Run by
Abeona Therapeutics, Inc
See details and how to joinNCT07700966
Phase 1/2Taking people
Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullosa
Where
Redwood City
Age
6 years and over
People
8
Run by
M. Peter Marinkovich
See details and how to joinNCT06834035
Phase 1/2Not yet taking people in United States
Targeting Collagen VII Antibodies in Bullous Diseases Using Efgartigimod IV (VYVGART)
Where
Redwood City
Age
12 years and over
People
18
Run by
M. Peter Marinkovich
See details and how to joinNCT07011589
Early phase 1Taking people
Repurposing Dupilumab for Management of Pruritic Genetic Inflammatory Skin Disorders
Where
Chicago
Age
6 months and over
People
30
Run by
Northwestern University
See details and how to joinNCT05649098
No phaseTaking people
Characteristics of Patients With Recessive Dystrophic Epidermolysis Bullosa
Where
Stanford
People
70
Run by
Stanford University
See details and how to joinNCT01019148
Phase 2Taking people
Impact of COL7A1 Gene Therapy on SCC Recurrence in RDEB Skin
Where
Redwood City
Age
18 years and over
People
16 worldwide
Run by
Stanford University
See details and how to joinNCT06731933
Phase 3Taking people
A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa
Where
Cincinnati, Coral Gables, Rancho Santa Margarita, San Antonio, Worcester
Age
6 months and over
People
16
Run by
Krystal Biotech, Inc.
See details and how to joinNCT07016750
No phaseTaking people
A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB)
Where
Pittsburgh
Age
6 months and over
People
40
Run by
Krystal Biotech, Inc.
See details and how to joinNCT06563414
Phase 1/2Taking people
MSC EVs in Dystrophic Epidermolysis Bullosa
Where
Los Angeles, Philadelphia, Phoenix
Age
6 months and over
People
8
Run by
Aegle Therapeutics
See details and how to joinNCT04173650
No phaseTaking people
Long-Term Follow-up Protocol
Where
Coral Gables, Rancho Santa Margarita, Redwood City
Age
6 months and over
People
50
Run by
Krystal Biotech, Inc.
See details and how to joinNCT04917887
Phase 1/2Taking people
Gentamicin for Junctional Epidermolysis Bullosa
Where
Los Angeles
People
6
Run by
University of Southern California
See details and how to joinNCT03526159