Epilepsy trials in United Kingdom

In United Kingdom 25 Also abroad 451

25 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1
Where
Plymouth
Age
18 years to 75 years
People
333 worldwide
Run by
Rapport Therapeutics Inc.
See details and how to joinNCT07563881
Phase 3Taking people
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Where
Cardiff, London, Oxford, Salford, Wakefield
Age
12 years and over
People
160 worldwide
Run by
Xenon Pharmaceuticals Inc.
See details and how to joinNCT05667142 · EU 2022-502286-16-00
Phase 3Enrolling by invitation
An Open-label Study of XEN1101 in Epilepsy
Where
Birmingham, Cardiff, Leeds, London, Oxford, Salford
Age
12 years and over
People
880 worldwide
Run by
Xenon Pharmaceuticals Inc.
See details and how to joinNCT05718817 · EU 2022-502282-24-00
Phase 3Taking people
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
Where
Cardiff, London, Sheffield
Age
2 years and over
People
150 worldwide
Run by
Epygenix
See details and how to joinNCT04462770 · EU 2024-518628-57-00
Phase 1/2Taking people
A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
Where
Glasgow, London
Age
6 months to 17 years
People
113 worldwide
Run by
Encoded Therapeutics
See details and how to joinNCT05419492
No phaseTaking people
An Observational Study of Epilepsy: Biology and Outcomes Using Real-world Data
Where
Cardiff
Age
16 years and over
People
2,000
Run by
Cardiff and Vale University Health Board
See details and how to joinNCT05632978
No phaseTaking people
Artificial Intelligence for Brain MRI Analysis in Epilepsy
Where
London
People
2,000 worldwide
Run by
Istituto Giannina Gaslini
See details and how to joinNCT07881185
Phase 3Enrolling by invitation
A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)
Where
Cardiff, Glasgow, London, Newcastle upon Tyne
Age
2 years to 66 years
People
324 worldwide
Run by
Longboard Pharmaceuticals
See details and how to joinNCT06908226 · EU 2024-514974-39-00
No phaseTaking people
Prospective Natural History Study of POLG Disease
Where
Cambridge, London
People
300 worldwide
Run by
The POLG Foundation
See details and how to joinNCT07775872
Phase 3Not yet taking people in United Kingdom
COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"
Where
London
Age
2 years and over
People
438 worldwide
Run by
Yale University
See details and how to joinNCT07281027
No phaseTaking people
Electrical Impedance Tomography & Selective Stimulation of Vagus Nerve
Where
London
Age
18 years and over
People
50
Run by
University College, London
See details and how to joinNCT05664854
Phase 2Enrolling by invitation
Long-term Safety and Tolerability of BHV-7000
Where
Cardiff, Glasgow, Liverpool, London, Newcastle upon Tyne, Oxford, Salford, Swansea
Age
18 years to 75 years
People
660 worldwide
Run by
Biohaven Therapeutics Ltd.
See details and how to joinNCT06443463 · EU 2023-508813-18-00
No phaseTaking people
The Clinical Utility of BioEP in Diagnostic Decision Making in Epilepsy
Where
Truro, Wolverhampton
Age
18 years and over
People
559
Run by
Neuronostics Ltd
See details and how to joinNCT06097195
No phaseTaking people
The PARS Study: Paediatric Advanced Respiratory Service Study - An Observational Diagnostic Feasibility Study
Where
Glasgow
Age
1 Minute to 16 years
People
225
Run by
NHS Greater Clyde and Glasgow
See details and how to joinNCT06292299
No phaseTaking people
The Children's Adaptive Deep Brain Stimulation for Epilepsy Trial
Where
London
Age
5 years to 14 years
People
22
Run by
University College, London
See details and how to joinNCT06924086
No phaseTaking people
Thalamic Recordings in Children Undergoing SEEG
Where
London
Age
2 years to 20 years
People
30
Run by
Great Ormond Street Hospital for Children NHS Foundation Trust
See details and how to joinNCT06453759
No phaseEnrolling by invitation
OPM MEG in Pre-surgical Mapping for Patients With Epilepsy
Where
Birmingham
Age
6 years to 15 years
People
20
Run by
Aston University
See details and how to joinNCT07378397
No phaseNot yet taking people in United Kingdom
Compassion Focussed Therapy Informed Psychoeducation and Loving Kindness Meditation for Young People With Epilepsy
Where
Lincoln
Age
12 years to 17 years
People
3
Run by
University of Lincoln
See details and how to joinNCT07265362
No phaseTaking people
REACH: RWE Retrospective Study to Evaluate Cenobamate Impact on Health Care Resource Utilization
Where
Glasgow, Wolverhampton
Age
18 years and over
People
200 worldwide
Run by
Aziende Chimiche Riunite Angelini Francesco S.p.A
See details and how to joinNCT06922175
No phaseTaking people
Biology of Juvenile Myoclonic Epilepsy
Where
Liverpool, London, Swansea
Age
10 years to 40 years
People
1,000 worldwide
Run by
King's College London
See details and how to joinNCT03400371
No phaseTaking people
Neurofrailty: A Study of Late-onset Epilepsy and Its Associations
Where
Preston
Age
18 years and over
People
360
Run by
Lancashire Teaching Hospitals NHS Foundation Trust
See details and how to joinNCT06263920
No phaseTaking people
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Where
Wolverhampton
Age
6 years and over
People
200,000
Run by
Future Genetics Limited
See details and how to joinNCT03987633
No phaseTaking people
Study of Patients with Electrical Status Epilepticus in Sleep
Where
Colchester
Age
1 year to 16 years
People
20
Run by
East Suffolk and North Essex NHS Foundation Trust
See details and how to joinNCT06792396
No phaseTaking people
Volatile Non-Invasive Biomarkers of Epileptic Seizures
Where
London
Age
18 years and over
People
270
Run by
University College London Hospitals
See details and how to joinNCT05725174
No phaseTaking people
National Registry of Rare Kidney Diseases
Where
Bristol
People
35,000
Run by
UK Kidney Association
See details and how to joinNCT06065852