Familial hypercholesterolaemia trials in Brazil

6 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

• Phase 2/3Taking people
  A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)

  Where

  Fortaleza, São Paulo

  Age

  6 years to 17 years

  People

  153 worldwide

  Run by

  Merck Sharp & Dohme LLC

  See details and how to joinNCT07058077 · EU 2024-519068-42-00
• No phaseTaking people
  A Study of Bempedoic Acid or Its Single-pill Combination Therapy With Ezetimibe in Patients With Primary Hypercholesterolaemia or Mixed Dyslipidaemia

  Where

  Belo Horizonte, Blumenau, Caixias Do Sul, Campina Grande do Sul, Curitiba, Joinville, Juiz de Fora, Maringá, Pocos de Calda, Porto Alegre, Salvador, Santo André, São Paulo, Tatuí

  Age

  18 years and over

  People

  2,120 worldwide

  Run by

  Daiichi Sankyo

  See details and how to joinNCT07206472
• Phase 3Taking people
  Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies

  Where

  Fortaleza, São Paulo

  Age

  2 years to 100 years

  People

  195 worldwide

  Run by

  Novartis Pharmaceuticals

  See details and how to joinNCT05682378
• Phase 3Taking people
  Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

  Where

  Fortaleza, Porto Alegre, Rio de Janeiro, São Paulo

  Age

  6 years to 11 years

  People

  60 worldwide

  Run by

  Novartis Pharmaceuticals

  See details and how to joinNCT06597019
• No phaseTaking people
  National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry

  Where

  Belém, Belo Horizonte, Bragança Paulista, Brasília, Consolação, Fortaleza, Goiânia, Joinville, Macapá, Maceió, Montes Claros, Natal, Palmas, Porto Alegre, Porto Velho, Rio Branco, Rio de Janeiro, Salvador, São Carlos, São Paulo, Vila Velha

  People

  1,211

  Run by

  Hospital do Coracao

  See details and how to joinNCT06546137
• Phase 4Taking people
  LATAM LOWERS LDL-C

  Where

  Belo Horizonte, Blumenau, Campina Gde Do Sul, Campo Largo, Porto Alegre, Salvador, São José

  Age

  18 years to 100 years

  People

  520 worldwide

  Run by

  Novartis Pharmaceuticals

  See details and how to joinNCT06501443