Familial hypercholesterolaemia trials in France

In France 9 Also abroad 115

9 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2/3Taking people
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
Where
Bron, Toulouse Cedex 9
Age
6 years to 17 years
People
153 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07058077 · EU 2024-519068-42-00
Phase 3Taking people
Study to evaluate efficacy and safety of inclisiran in children aged 2 to under 12 years of age with homozygous familial hypercholesterolemia
Where
Paris
Age
Up to 17 years
People
8 worldwide
Run by
Novartis Pharma AG
See details and how to join2024-514595-41-00 · EU 2024-514595-41-00
Phase 3Taking people
Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies
Where
Besançon, Toulouse
Age
2 years to 100 years
People
195 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05682378
No phaseTaking people
Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administration on Coronary Plaque Volumes Measured by Coronary Computed Tomography Angiography (CCTA) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)
Where
Paris
Age
12 years and over
People
52 worldwide
Run by
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi)
See details and how to joinNCT07447648
No phaseTaking people
"Detection and Follow-up of Coronary Lesions in HeFH (DESTINY-FH Study)"
Where
Paris
Age
30 years to 60 years
People
300
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT07427472
Phase 3Taking people
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Where
Marseille, Nantes, Paris
Age
6 years to 11 years
People
60 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597019
No phaseTaking people
Study of the Determinants of Coronary Atherosclerosis in Familial Hypercholesterolemia (ATHERO-FH Study)
Where
Dijon, Lille, Lyon, Marseille, Nantes, Paris, Rennes, Strasbourg
Age
40 years and over
People
600
Run by
Nantes University Hospital
See details and how to joinNCT06960902
No phaseTaking people
Screening for Familial Hypercholesterolemia in Children
Where
Amiens
Age
2 years to 18 years
People
300
Run by
Centre Hospitalier Universitaire, Amiens
See details and how to joinNCT06555120
No phaseTaking people
Effect of LIMICOL®-NG on Plasma LDL-cholesterol Concentration in Subjects with Moderate Hypercholesterolemia
Where
Lille
Age
18 years to 70 years
People
35
Run by
Institut Pasteur de Lille
See details and how to joinNCT06894251