Familial hypercholesterolaemia trials in Germany

In Germany 7 Also abroad 116

7 of 7 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 2/3Taking people
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
Where
Freiburg im Breisgau, Hanover, Magdeburg
Age
6 years to 17 years
People
153 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07058077 · EU 2024-519068-42-00
Phase 3Taking people
Study to evaluate efficacy and safety of inclisiran in children aged 2 to under 12 years of age with homozygous familial hypercholesterolemia
Where
Frankfurt Am Main
Age
Up to 17 years
People
8 worldwide
Run by
Novartis Pharma AG
See details and how to join2024-514595-41-00
Phase 3Not yet taking people in Germany
A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events
Where
Berlin, Hamburg, Mainz, Mannheim
Age
18 years and over
People
103 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT07474649
Phase 3Active, not recruiting
Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies
Where
Frankfurt am Main, Freiburg im Breisgau
Age
2 years to 100 years
People
195 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05682378
Phase 3Taking people
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Where
Frankfurt am Main
Age
2 years to 11 years
People
9 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597006
Phase 4Taking people
Early TRIPLE versus dual LIPID lowering treatment in peOple with atherosclerotic cardiovascular disease and hypercholesterolemia Undergoing elecTive revascularisation
Where
Dresden, Mainz, Regensburg
Age
18 years and over
People
160 worldwide
Run by
Medical University Of Graz
See details and how to join2026-525917-29-00
Phase 3Taking people
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Where
Frankfurt am Main, Freiburg im Breisgau, Hanover
Age
6 years to 11 years
People
60 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597019