Familial hypercholesterolaemia trials in Netherlands

In Netherlands 10 Also abroad 115

10 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2/3Taking people
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
Where
Amsterdam
Age
6 years to 17 years
People
153 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07058077 · EU 2024-519068-42-00
Phase 3Taking people
Study to evaluate efficacy and safety of inclisiran in children aged 2 to under 12 years of age with homozygous familial hypercholesterolemia
Where
Amsterdam
Age
Up to 17 years
People
8 worldwide
Run by
Novartis Pharma AG
See details and how to join2024-514595-41-00 · EU 2024-514595-41-00
Phase 3Taking people
Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia
Where
Amsterdam
Age
12 years to 17 years
People
10 worldwide
Run by
Arrowhead Pharmaceuticals
See details and how to joinNCT07473843 · EU 2025-523662-24-00
Phase 1Taking people
Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia
Where
Amsterdam, Rotterdam
Age
18 years to 70 years
People
132 worldwide
Run by
Verve Therapeutics, Inc.
See details and how to joinNCT06451770 · EU 2025-522617-39-00
Phase 3Taking people
Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies
Where
Amsterdam, Rotterdam
Age
2 years to 100 years
People
195 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05682378
Phase 4Taking people
Optimizing therapy with n=1-studies: negating the 'nocebo' effect in statin-intolerance
Where
Amersfoort, Arnhem, Dordrecht, Ede Gld, Nijmegen, Rotterdam, Tilburg, Utrecht, Zwolle
Age
18 years and over
People
249
Run by
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
See details and how to join2023-507489-20-00 · EU 2023-507489-20-00
No phaseTaking people
Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administration on Coronary Plaque Volumes Measured by Coronary Computed Tomography Angiography (CCTA) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)
Where
Amsterdam, Rotterdam
Age
12 years and over
People
52 worldwide
Run by
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi)
See details and how to joinNCT07447648
Phase 3Taking people
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Where
Amsterdam
Age
2 years to 11 years
People
9 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597006
Phase 3Taking people
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Where
Amsterdam
Age
6 years to 11 years
People
60 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597019
No phaseTaking people
HoFH, the International Clinical Collaborators Registry
Where
Amsterdam
People
1,000 worldwide
Run by
University of Pennsylvania
See details and how to joinNCT04815005