Frontotemporal dementia trials in United Kingdom

4 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

• Phase 1Taking people
  A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

  Where

  London, Sheffield, Southampton

  Age

  50 years to 85 years

  People

  56 worldwide

  Run by

  Eli Lilly and Company

  See details and how to joinNCT06297590 · EU 2024-510604-37-00
• Phase 1/2Taking people
  A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

  Where

  Cambridge, Cardiff, London

  Age

  30 years to 75 years

  People

  18 worldwide

  Run by

  AviadoBio Ltd

  See details and how to joinNCT06064890 · EU 2023-509444-10-00
• Phase 3Taking people
  A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C

  Where

  London, Manchester

  Age

  4 years and over

  People

  53 worldwide

  Run by

  IntraBio Inc

  See details and how to joinNCT05163288
• No phaseTaking people
  The Imperial Comprehensive Cognitive Assessment in Cerebrovascular Disease (IC3)

  Where

  London

  Age

  18 years and over

  People

  700

  Run by

  Imperial College London

  See details and how to joinNCT05885295