Head and neck cancer trials in Netherlands

In Netherlands 31 Also abroad 942

31 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
Where
Amsterdam, Groningen, Maastricht
Age
18 years and over
People
600 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07276399 · EU 2025-521917-24-00
Phase 1/2Taking people
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
Where
Amsterdam, Nijmegen, Utrecht
Age
18 years and over
People
560 worldwide
Run by
Genmab
See details and how to joinNCT03526835 · EU 2024-513627-16-01
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Amsterdam, Groningen, Leiden, Maastricht, Nijmegen
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 1/2Taking people
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
Where
Amsterdam, Groningen, Nijmegen, Rotterdam, Utrecht
Age
18 years and over
People
680 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06330064 · EU 2023-509632-26-00
Phase 2Taking people
A Study Evaluating Ficerafusp Alfa (BCA101) QW in Combination With Pembrolizumab vs Alternative Ficerafusp Alfa Dosing in 1L R or M HNSCC
Where
Groningen, Nijmegen
Age
18 years and over
People
160 worldwide
Run by
Bicara Therapeutics
See details and how to joinNCT07807163 · EU 2026-526741-10-00
No phaseTaking people
Outcome Prediction in Head&Neck Cancer Patients After Radiotherapy
Where
Maastricht
Age
18 years and over
People
1,000
Run by
Maastricht Radiation Oncology
See details and how to joinNCT01985984
No phaseNot yet taking people in Netherlands
Off-line Adaptive Proton Therapy
Where
Groningen
Age
16 years and over
People
100
Run by
University Medical Center Groningen
See details and how to joinNCT07866547
Phase 3Taking people
IMCISION: Towards organ preservation and cure via ultra-short immunotherapy in advanced oral cancer. The IMCISION II trial, an investigator-initiated multicentre randomised phase 3 trial
Where
Amsterdam, Groningen, Leiden, Maastricht, Nijmegen, Rotterdam, Utrecht
Age
18 years and over
People
308
Run by
Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting
See details and how to join2025-522500-24-00 · EU 2025-522500-24-00
No phaseTaking people
To Assess the Correlation of High-resolution Specimen PET-CT Imaging, Using the XEOS AURA 10 PET-CT, With the Histopathology Results and Long-term Outcome of Patients Undergoing Resective Cancer Surgery.
Where
Groningen
Age
18 years and over
People
850 worldwide
Run by
XEOS Medical
See details and how to joinNCT06970275
Phase 2Taking people
Fluorescence-guided Surgery in Laryngeal- and Hypopharyngeal Cancer: a Feasibility Trial
Where
Rotterdam
Age
18 years and over
People
27
Run by
Erasmus Medical Center
See details and how to joinNCT05752149
Phase 1Taking people
Thermotherapy for Head and Neck Cancer Patients
Where
Rotterdam
Age
18 years and over
People
30
Run by
Erasmus Medical Center
See details and how to joinNCT07690618
Phase 1Taking people
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Where
Amsterdam
Age
18 years and over
People
714 worldwide
Run by
Seagen, a wholly owned subsidiary of Pfizer
See details and how to joinNCT05208762 · EU 2023-506604-18-00
Phase 1/2Taking people
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
Where
Amsterdam, Rotterdam
Age
18 years and over
People
880 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT05768139 · EU 2023-504807-94-00
Phase 1Taking people
A Phase 1 Open-label Study to Evaluate the Safety and Efficacy of MK‑8294 Monotherapy in Advanced Solid Tumors
Where
Amsterdam, Nijmegen
Age
18 years and over
People
21
Run by
Merck Sharp & Dohme LLC
See details and how to join2024-516870-31-00 · EU 2024-516870-31-00
Phase 2/3Not yet taking people in Netherlands
The Surf trial
Where
Rotterdam
Age
18 years and over
People
40
Run by
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
See details and how to join2025-523898-42-00 · EU 2025-523898-42-00
Phase 3Taking people
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma
Where
Amsterdam, Nijmegen
Age
18 years and over
People
410 worldwide
Run by
AVEO Pharmaceuticals, Inc.
See details and how to joinNCT06064877 · EU 2023-505606-42-00
No phaseTaking people
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
Where
Amsterdam, Deventer, Leeuwarden, Nijmegen, Utrecht
Age
18 years and over
People
8,000 worldwide
Run by
UMC Utrecht
See details and how to joinNCT04075305
Phase 2/3Taking people
Contrast-enhanced Ultrasound for Sentinel Node Detection
Where
Amsterdam
Age
18 years and over
People
91
Run by
The Netherlands Cancer Institute
See details and how to joinNCT07310758
Early phase 1Taking people
PET-imaging of Two Vartumabs in Patients With Solid Tumors
Where
Groningen
Age
18 years and over
People
32
Run by
Var2 Pharmaceuticals
See details and how to joinNCT06645808 · EU 2024-513827-18-00
Phase 3Taking people
Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Larynx and Pharynx Cancer. The PRIMO Study.
Where
Amsterdam, Arnhem, Enschede, Groningen, Leiden, Maastricht, Nijmegen, Rotterdam, Utrecht
Age
18 years and over
People
242
Run by
Radboud University Medical Center
See details and how to joinNCT05333523
Phase 1/2Taking people
Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI
Where
Maastricht, Rotterdam
Age
18 years and over
People
126 worldwide
Run by
Maastricht University Medical Center
See details and how to joinNCT04954599
No phaseTaking people
Telemedicine Follow-Up for Early Laryngeal Cancer: a Randomized Controlled Trial Comparing Care Close to Home Versus Standard of Care
Where
Groningen
Age
18 years and over
People
140
Run by
University Medical Center Groningen
See details and how to joinNCT06940505
No phaseTaking people
Feasibility of CBCT-Guided Online Adaptive Radiotherapy (FASCINATE)
Where
Amsterdam
Age
18 years and over
People
100
Run by
The Netherlands Cancer Institute
See details and how to joinNCT06691776
Phase 2Taking people
Towards Cure Via Only Ultra-short ICB in CSCC
Where
Amsterdam, Maastricht, Rotterdam, Utrecht
Age
18 years and over
People
41
Run by
The Netherlands Cancer Institute
See details and how to joinNCT06823479 · EU 2024-516152-17-00
Phase 1/2Not yet taking people in Netherlands
Molecular Imaging of DNA Damage Response by [18F]-Olaparib PET
Where
Groningen
Age
18 years and over
People
10
Run by
University Medical Center Groningen
See details and how to joinNCT06482307 · EU 2024-511962-34-00