Heart failure: open trials in Canada

78 open trials have a site in Canada. Registry data; only the trial team decides who can take part.

NCT05859048
Multidisciplinary Approach for High Risk Patients Leading to Early Diagnosis of Canadians in Heart Failure
Trial Treatment · Cardiology Research UBC
Montreal Heart Institute, Montreal · University of Sherbrooke, Sherbrooke · Vancouver General Hospital, Vancouver
Registry updated 2026-11-05
NCT06547788
LEFT ATRIAL MONITORING IN PATIENTS BEFORE AND AFTER MITRAL SURGERY - LAMBDA STUDY
Trial Treatment · Ottawa Heart Institute Research Corporation
University of Ottawa Heart Institute, Ottawa
Registry updated 2026-11-05
NCT07434466
Ketone Ester for Treatment Of Acute Heart Failure
Trial Treatment · University of Alberta
University of Alberta, Edmonton
Registry updated 2026-11-05
NCT00271180
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
Research · Medtronic
Calgary · Kingston · Montreal · Québec
Registry updated 2026-11-04
NCT06736574
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Trial Treatment · Phase 3 · Cytokinetics
Mazankowski Alberta Heart Institute / University of Alberta Hospital, Edmonton · Kelowna General Hospital, Kelowna · Kingston Health Sciences Centre, Kingston · London Health Sciences Centre, London · Montreal Heart Institute, Montreal · Oakville Trafalgar Memorial Hospital - Halton Healthcare, Oakville · Diex Recherche Sherbrooke, Sherbrooke · SMH - Cardiology Clinical Trials Inc., Surrey · CISSSL - Hopital Pierre-Le Gardeur, Terrebonne · UHN-Toronto General Hospital, Toronto · St. Michael's Hospital, Toronto · Sunnybrook Health Sciences Centre, Toronto · St. Paul's Hospital, Vancouver · Victoria Heart Institute Foundation, Victoria · St. Boniface Hospital, Winnipeg
Registry updated 2026-11-04
NCT06678841
ELEVATE-HFpEF Clinical Study
Trial Treatment · Medtronic Cardiac Rhythm and Heart Failure
University Of Calgary, Calgary · Saint Pauls Hospital, Vancouver
Registry updated 2026-11-03
NCT05714085
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Trial Treatment · Phase 2/3 · Merck Sharp & Dohme LLC
Stollery Children's Hospital ( Site 0501), Edmonton · Centre intégré universitaire de santé et de services sociaux-Centre de recherche du CHUS ( Site 0502), Sherbrooke · The Hospital for Sick Children ( Site 0500), Toronto
Registry updated 2026-10-30
NCT07037459
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Trial Treatment · Phase 3 · Amgen
Brampton Clinical Trials, Brampton · Cambridge Cardiac Care Centre, Cambridge · Saul Vizel Professional Medicine Corporation - Vizel Cardiac Research, Cambridge · Ecogene-21, Chicoutimi · University of Alberta Hospital, Edmonton · Montreal Heart Institute, Montreal · Partners in Advanced Cardiac Evaluation, Newmarket · North York Diagnostic and Cardiac Centre, North York · Kawartha Cardiology Clinical Trials, Peterborough · CardioQuest Research Centre, Sarnia · Heart Health Institute Research Incorporated, Scarborough Village · Diex Recherche Sherbrooke Est, Sherbrooke · KMH Cardiology Centres Incorporated Hamilton, Stoney Creek · Curans Heart Center, Thunder Bay · Diabetes Heart Research Centre, Toronto · Womens College Hospital, Toronto · Diex Recherche Trois-Rivieres, Trois-Rivières · CPS Research, Waterloo · Winchester District Memorial Hospital, Winchester · St. Boniface Hospital, Winnipeg · Cardio 1, Winnipeg
Registry updated 2026-10-29
NCT06424288
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Trial Treatment · Phase 3 · Boehringer Ingelheim
Cambridge Cardiac Care Centre, Cambridge · Royal Alexandra Hospital (Edmonton), Edmonton · Health Sciences North, Greater Sudbury · ViaCar Recherches Cliniques Inc. (Greenfield Park), Greenfield Park · Curnew Medicine Professional Corporation, Hamilton · Clinical Research Solutions Inc. (Kitchener), Kitchener · KMH Cardiology Centres (Mississauga), Mississauga · Montreal General Hospital - McGill University Health Centre, Montreal · Centre Hospitalier de l'Universite de Montreal (CHUM), Montreal · Jewish General Hospital, Montreal · Oakville Trafalgar Memorial Hospital, Oakville · James Cha, MD, Oshawa · Kawartha Cardiology Clinical Trials, Peterborough · CardioVasc HR Inc., Saint-Jean-sur-Richelieu · CardioQuest Research Centre, Sarnia · KMH Cardiology Centres (Hamilton), Stoney Creek · Diabetes Heart Research Centre, Toronto · Diex Recherche Trois-Rivieres, Trois-Rivières
Registry updated 2026-10-28
NCT06935370
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Trial Treatment · Phase 3 · Boehringer Ingelheim
ViaCar Recherches Cliniques Inc. (Brossard), Brossard · Saul Vizel Medicine Professional Corporation, Cambridge · Health Sciences North, Greater Sudbury · Premier Clinical Trial Network, Hamilton · Elevate Clinical Research - KMH Hamilton, Kitchener · KMH Cardiology Centres (Mississauga), Mississauga · Oakville Trafalgar Memorial Hospital, Oakville · James Cha, MD, Oshawa · Kawartha Cardiology Clinical Trials, Peterborough · CIUSSS du Saguenay Lac-Saint-Jean, Québec · Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Québec · CardioQuest Research Centre, Sarnia · Diex Recherche Sherbrooke, Sherbrooke · Diex Recherche Trois-Rivieres, Trois-Rivières · Fadia El Boreky Medicine Professional Corporation, Waterloo
Registry updated 2026-10-28
NCT07192952
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Trial Treatment · Phase 3 · Bayer
Stollery Children's Hospital | Cardiology, Edmonton · Children's Hospital | Cardiology, London · Centre hospitalier universitaire Sainte-Justine | Cardiology, Montreal · Royal University Hospital | Cardiology, Saskatoon · The Hospital for Sick Children (SickKids) | Cardiology, Toronto · BC Children's Hospital | Children's Heart Centre, Vancouver
Registry updated 2026-10-27
NCT07893821
Renal Denervation in Patients With Atrial Fibrillation and Hypertension
Trial Treatment · Pavel Antiperovitch
London Heart Rhythm Program, London
Registry updated 2026-10-26
NCT06991257
A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
Trial Treatment · Phase 2 · Pfizer
CIUSSS- saguenay-Lac-Saint-Jean, Chicoutimi · Health Sciences North Research Institute, Greater Sudbury · ACV Clinic, Greater Sudbury · QEII Health Sciences Centre, Victoria General Site, Halifax · CHU de Quebec-Universite Laval-Hotel Dieu de Quebec, Québec · Richmond Clinical Trials, Richmond · CardioQuest Research Centre, Sarnia · Clinique de Médecins Spécialistes, Shebrooke · Diex Recherche Sherbrooke Est, Sherbrooke · Centre intégré de santé et de services sociaux de Lanaudière - Hopital Pierre-Le Gardeur., Terrebonne · Corcare, Toronto · Diex Recherche Trois-Rivieres, Trois-Rivières · Winchester District Memorial Hospital, Winchester · Community Care Building, Winchester
Registry updated 2026-10-23
NCT07059962
Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)
Research · Bodyport Inc.
St. Joseph's Health Centre, Toronto · St. Michael's Hospital, Toronto · Seven Oaks General Hospital, Winnipeg
Registry updated 2026-10-22
NCT05961176
Exploratory Study on Bio-signal Telemonitoring Using Electronic Textiles in a Pediatric Acute and Critical Care Setting
Research · The Hospital for Sick Children
The Hospital for Sick Children (SickKids), Toronto
Registry updated 2026-10-21
NCT06677060
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Trial Treatment · Phase 3 · AstraZeneca
Abbotsford British Columbia · Calgary · Cambridge · Guelph · Halifax · Hamilton · Laval · Lévis · Markham · Mirabel · Moncton · Montreal · Newmarket · North York · Oakville · Ottawa · Québec · Regina · Saint-Charles-Borromée · Saint John · Sarnia · Scarborough Village · Sherbrooke · Sherwood Park · St. John's · Sydney · Terrebonne · Toronto · Trois-Rivières
Registry updated 2026-10-21
NCT07207811
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Trial Treatment · Phase 3 · Novo Nordisk A/S
University Of Calgary, Calgary · Health Sciences North Research Institute-Advanced Medical Research Institute of Canada, Greater Sudbury · Nova Scotia Health Authority, Halifax · Cardio Health Clinical Trials, Hamilton · Cardio Health Clinical Trials, Kitchener · London Health Sciences Centre, University Hospital, London · Cardio Health Clinical Trials, Mississauga · University of Ottawa - Heart Institute (UOHI) (Institut de Cardiologie de L'Universite d'Ottawa), Ottawa · Hotel-Dieu de Quebec, Québec · CIUSSS du Saguenay Lac-Saint-Jean, Québec · Centre Hospitalier Regional De Rimouski, Rimouski · Cardio Health Clinical Trials, Scarborough Village · Riverside Cardiology and Diagnostic Imaging, Toronto · Vancouver General Hospital, Vancouver
Registry updated 2026-10-21
NCT07272902
Treating Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: Ablation or Medication
Trial Treatment · Nova Scotia Health Authority
QEII HSC, Halifax · Hamilton Health Sciences, Hamilton · London Health Sciences Centre, London · Montreal Heart Institute, Montreal
Registry updated 2026-10-20
NCT05427370
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
Trial Treatment · Sunnybrook Health Sciences Centre
University of Calgary; Libin Cardiovascular Institute, Calgary · Mackenzie Health Sciences Center, Edmonton · Queen Elizabeth II Hospital, Halifax · Hamilton General Hospital, Hamilton · London Health Sciences Center, University Hospital, London · Hospital Sacre-Coeur, Montreal · Center Hospitalier Universitaire de Montreal, Montreal · Jewish General Hospital, Montreal · Montreal Heart Institute, Montreal · Southlake Regional HC, Newmarket · Fraser Health; Royal Columbian Hospital, New Westminster · Ottawa Heart Institute, Ottawa · Institut de Cardiologie Quebec (QC) - Laval, Québec · St. Michael's, Toronto · Toronto General Hospital, Toronto · Sunnybrook Health Sciences Center, Toronto · Providence Health, Vancouver · The University of Manitoba and St. Boniface Hospital Inc., Winnipeg
Registry updated 2026-10-19
NCT07727304
Implementation of Acute Heart Failure Checklist
Trial Treatment · Ottawa Hospital Research Institute
Ottawa Hospital Research Institute, Ottawa
Registry updated 2026-10-16
NCT06570473
Feasibility Trial for a Right Ventricular Failure Platform Trial
Trial Treatment · Phase 2 · University of Alberta
University Of Calgary, Calgary · University of Alberta, Edmonton · London Health Sciences Centre, University Hospital, London · The Ottawa Hospital, Ottawa · The University of British Columbia, Vancouver
Registry updated 2026-10-15
NCT07188805
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Trial Treatment · Phase 3 · Bayer
Stollery Children's Hospital | Cardiology, Edmonton · Children's Hospital | Cardiology, London · Centre hospitalier universitaire Sainte-Justine | Cardiology, Montreal · Royal University Hospital | Cardiology, Saskatoon · The Hospital for Sick Children (SickKids), Toronto · BC Children's Hospital | Children's Heart Centre, Vancouver
Registry updated 2026-10-15
NCT06307652
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Trial Treatment · Phase 3 · AstraZeneca
Cambridge · Chicoutimi · Greenfield Park · Hamilton · London · Montreal · Newmarket · New Westminster · North Vancouver · North York · Oakville · Oshawa · Ottawa · Peterborough · Saint-Jean-sur-Richelieu · Sydney · Thunder Bay · Toronto · Trois-Rivières · Vancouver · Waterloo · Winnipeg
Registry updated 2026-10-13
NCT06812533
Alleviant ALLAY-HFrEF Study
Trial Treatment · Alleviant Medical, Inc.
Centre Hospitalier de l'Universite de Montreal (CHUM), Montreal · Centre Integre Universitaire de Sainte et de Services Scoiiaux de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke (CIUSSS de l'Estrie - CHUS), Montreal · Southlake Regional Hospital Centre, Newmarket · IUCPQ - Université Laval (Quebec), Québec
Registry updated 2026-10-06
NCT05434819
Surgical Ablation of AF Efficacy Trial
Trial Treatment · Population Health Research Institute
Hamilton General Hospital, Hamilton
Registry updated 2026-10-05

All Heart failure trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Report an error