Heart failure: open trials in Canada

• NCT06979362

  A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

  Trial Treatment · Phase 2 · Novo Nordisk A/S

  William Osler Hel Bra Civic Hs, Brampton · Cardio Health Clinical Trials, Hamilton · Hamilton General Hospital, Hamilton · Hamilton Hlth Sc. - General Site, Hamilton · Premier Clinical Trial Research Network (PCTRN), Hamilton · Cardio Health Clinical Trials, Mississauga · University of Ottawa Heart Institute (UOHI), Ottawa · IUCPQ-Universite Laval, Québec · Women's College Hospital, Toronto · St. Michael's Hospital, Toronto · St Pauls Hospital, Vancouver · Winchester Dist Memorial Hosp, Winchester

  Registry updated 2026-10-05

• NCT05873881

  COLchicine and Thiamine in Heart Failure Due to Ischemic Heart Disease

  Trial Treatment · Phase 3 · Hamilton Health Sciences Corporation

  Hamilton Health Sciences Corporation, Hamilton

  Registry updated 2026-10-02

• NCT07465653

  A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction

  Trial Treatment · Phase 1 · Novartis Pharmaceuticals

  Montreal

  Registry updated 2026-10-01

• NCT07761117

  A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

  Trial Treatment · Phase 3 · AstraZeneca

  Barrie · Etobicoke · Greater Sudbury · Hamilton · Kingston · London · Markham · Montreal · Newmarket · North York · Oakville · Ottawa · Stoney Creek · Thunder Bay · Toronto · Trois-Rivières

  Registry updated 2026-09-28

• NCT06008197

  A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

  Trial Treatment · Phase 3 · Colorado Prevention Center

  Calgary · Cambridge · Edmonton · Edmonton · Greater Sudbury · Kamloops · London · North Vancouver · North York · Regina · Sherbrooke · Surrey · Toronto · Toronto · Toronto · Vancouver · Winnipeg

  Registry updated 2026-09-10

• NCT06024746

  A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

  Trial Treatment · Phase 3 · Colorado Prevention Center

  CON-11011, Edmonton, AB, Edmonton · CON-11016, Sudbury, ON, Greater Sudbury · CON-11010, London, ON, London · CON-11026, Montreal, Quebec, Montreal · North York · Sherbrooke · Surrey · CON-11019, Toronto, ON, Toronto · CON-11001, Toronto, ON, Toronto · CON-11008, Toronto, ON, Toronto

  Registry updated 2026-09-10

• NCT06405555

  Midodrine in Heart Failure With Reduced Ejection Fraction With Hypotension

  Trial Treatment · Phase 2/3 · Ottawa Heart Institute Research Corporation

  University of Ottawa Heart Institute, Ottawa

  Registry updated 2026-09-08

• NCT06601465

  COgnitioN With VERiciGuat Evaluation in Heart Failure

  Trial Treatment · Phase 2 · University of Alberta

  University Of Calgary, Calgary · University of Alberta, Edmonton · McGill University Health Center, Montreal · University of Ottawa, Ottawa

  Registry updated 2026-08-25

• NCT04278404

  Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

  Research · Duke University

  CHU Sainte-Justine, Montreal · The Hospital for Sick Children, Toronto

  Registry updated 2026-08-21

• NCT07567001

  A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

  Trial Treatment · Phase 3 · Novo Nordisk A/S

  Circulate Cardiac and Vascular Centre, Burlington · University Of Calgary, Calgary · CIUSSS du Saguenay Lac St-Jean, Chicoutimi · Med Trust Research, Inc., Courtice · Nova Scotia Health, Halifax · Curnew Medicine Professional Corporation, Hamilton · Cardio Health Clinical Trials, Hamilton · Cardiac Institute for Research at Queen's - CIRQ, Kingston · G.A. Research Associates, Ltd., Moncton · CHUM-Hosp de Univ Montreal, Montreal · North York Diagn & Cardiac Ctr, North York · Halton Healthcare, Oakville · Kawartha Cardiology Clinical Trials, Peterborough · IUCPQ-Universite Laval, Québec · CHU de Quebec-Uni Laval-Hotel, Québec · CISSS BAS ST-LAURENT, HOPITAL regional DE RIMOUSKI, Rimouski · C.I.C. Joliette, Saint-Charles-Borromée · Corcare Cardiovascular Research, Scarborough Village · Diex Recherche Sherbrooke, Sherbrooke · St. Joseph's Heath Centre, Toronto · Women's College Hospital, Toronto · Diabetes Heart Research Centre, Toronto · Diex Recherche Trois-Rivieres, Trois-Rivières · St Pauls Hospital, Vancouver · CPS Research, Waterloo · Winchester Dist Memorial Hosp, Winchester · St. Boniface Hospital, Winnipeg

  Registry updated 2026-08-18

• NCT05685303

  Alleviant ALLAY-HF Study

  Trial Treatment · Alleviant Medical, Inc.

  Centre Hospitalier de l'Universite de Montreal (CHUM), Montreal · Centre Integre Universitaire de Sainte et de Services Scoiiaux de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke (CIUSSS de l'Estrie - CHUS), Montreal · Southlake Regional Hospital Centre, Newmarket

  Registry updated 2026-08-14

• NCT05724433

  VIrtual Care To Improve Outcomes and RecoverY From Heart Failure Hospitalization

  Trial Treatment · Population Health Research Institute

  Juravinski Hospital Cancer Centre, Hamilton · St. Joseph's Healthcare Hamilton, Hamilton · Hamilton General Hospital, Hamilton · Thunder Bay Regional Health Sciences Centre, Thunder Bay · Unity Health Toronto, Toronto

  Registry updated 2026-08-07

• NCT07695090

  Lumacaftor Yields Reversal of Impaired Cerebral Blood Flow in Heart Failure Patients

  Trial Treatment · Phase 2 · Qanatpharma AG

  St. Michael's Hospital, Toronto · University Health Network (UHN) Peter Munk Cardiac Centre, Toronto

  Registry updated 2026-07-17

• NCT06033950

  A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

  Trial Treatment · Phase 3 · Colorado Prevention Center

  Calgary, AB Investigative Site FIN-11009, Calgary · FIN-11028, Edmonton, AB, Edmonton · FIN-11011, Edmonton, AB, Edmonton · FIN-11016, Sudbury, ON, Greater Sudbury · FIN-11024, Kingston, ON, Kingston · FIN-11010, London, ON, London · FIN-11020, North Vancouver, BC, North Vancouver · FIN-11007, North York, ON, North York · FIN-11005, Sherbrooke, QC, Sherbrooke · Surrey · FIN-11008, Toronto, ON, Toronto · FIN-11019, Toronto, ON, Toronto · FIN-11025, Victoria, BC, Victoria · FIN-11006, Winnipeg, MB, Winnipeg

  Registry updated 2026-07-10

• NCT06183437

  The STOP-MED CTRCD Trial

  Trial Treatment · Phase 4 · Dinesh Thavendiranathan

  Cardio-Oncology Clinic, MAHI, University of Alberta Hospital, Edmonton · Hamilton General Hospital, Hamilton · University of Ottawa Heart Institute, Ottawa · St. Michael's Hospital, Toronto · University Health Network, Toronto · St. Boniface Hospital, Winnipeg

  Registry updated 2026-07-07

• NCT07447908

  Ted Rogers Understanding of Exacerbations in Heart Failure 2: Monitor

  Research · University Health Network, Toronto

  Southlake Health, Newmarket · Sunnybrook Health Sciences Center, Toronto · 200 Elizabeth Street, Toronto

  Registry updated 2026-07-06

• NCT06299514

  RAFT - Pace &Ablate

  Trial Treatment · Habib Khan

  Nova Scotia Health Authority, Halifax · Hamilton Health Sciences Corporation, Hamilton · Waterloo Wellington Cardiovascular Research Institute, Kitchener · London Health Sciences Centre, University Hospital, London · Centre Hospitalier de l'Universite de Montreal (CHUM), Montreal · Montreal Heart Institute, Montreal · Southlake Regional Health Centre, Newmarket · Ottawa Heart Institute Research Corporation, Ottawa · Institut universitaire de cardiologie et de pneumologie Québec - Université Laval (IUCPQ-ULaval), Québec · Hôpital Fleurimont, Sherbrooke · Sunnybrook Health Sciences Centre, Toronto · Victoria Cardiac Arrhythmia Trials, Victoria

  Registry updated 2026-07-01

• NCT07556185

  MedlyPeds Feasibility Study

  Trial Treatment · The Hospital for Sick Children

  The Hospital for Sick Children, Toronto

  Registry updated 2026-06-26

• NCT05450328

  Inhaled Milrinone and Epoprostenol for the Prevention of Difficult Cardiac Pulmonary Bypass Separation

  Trial Treatment · Phase 2 · Montreal Heart Institute

  Montreal Heart Institute, Montreal

  Registry updated 2026-06-25

• NCT06930521

  JUdicious Surveillance for Trastuzumab Induced Cardiotoxicity in the First Year

  Trial Treatment · Women's College Hospital

  Toronto General Hospital, Toronto

  Registry updated 2026-06-15

• NCT05376254

  3D Assessment of RV Function in Patients Undergoing LVAD Implantation

  Research · University of Alberta

  Mazankowski Alberta Heart Institute, Edmonton

  Registry updated 2026-05-29

• NCT07609381

  Clinical Information System Impact on Hospitalized Patients With Chronic Disease

  Research · University of Calgary

  University Of Calgary, Calgary

  Registry updated 2026-05-27

• NCT01790152

  Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

  Research · Children's Oncology Group

  Alberta Children's Hospital, Calgary · McMaster Children's Hospital at Hamilton Health Sciences, Hamilton · Centre Hospitalier Universitaire Sainte-Justine, Montreal · The Montreal Children's Hospital of the MUHC, Montreal · Children'S Hospital Of Eastern Ontario, Ottawa · Centre hospitalier universitaire de Québec, Québec · Hospital for Sick Children, Toronto

  Registry updated 2026-05-18

• NCT06969560

  WeRoaM: Wearable Remote Monitoring in Heart Failure

  Research · University of Alberta

  Stollery Children'S Hospital, Edmonton · CHU Sainte-Justine, Montreal · The Hospital for Sick Children, Toronto · BC Children ' s Hospital, Vancouver

  Registry updated 2026-05-11

• NCT03999138

  MRI Assessment of Pulmonary Edema in Acute Heart Failure

  Research · University of Alberta

  University of Alberta, Edmonton · University of Ottawa Heart Institute, Ottawa

  Registry updated 2026-05-08

All Heart failure trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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