Heart failure trials in Germany

In Germany 111 Also abroad 1265

111 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Intrahospital Influenza Vaccination in Patients at High Cardiovascular Risk (VACC-UP)
Where
Cologne, Hamburg
Age
18 years and over
People
482
Run by
Stephan Baldus
See details and how to joinNCT07721649
No phaseTaking people
A Study to Learn About the Use of Acoramidis in Patients With a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world Setting
Where
Multiple Locations
Age
18 years and over
People
2,000 worldwide
Run by
Bayer
See details and how to joinNCT07235462
Phase 2Taking people
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Where
Berlin, Dresden, Essen, Frankfurt Am Main, Halle Saale, Hanover, Heidelberg, Kiel
Age
40 years to 84 years
People
200 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT06979362 · EU 2024-515796-35-00
No phaseNot yet taking people in Germany
Remote Monitoring and Optimization of Heart Failure Therapy
Where
Giessen
Age
18 years to 85 years
People
800 worldwide
Run by
Zoll Medical Corporation
See details and how to joinNCT07622472
No phaseTaking people
Early Feasibility Study of the Edwards APTURE Transcatheter Shunt System
Where
Cologne, Dresden, Mainz
Age
18 years and over
People
15
Run by
Edwards Lifesciences
See details and how to joinNCT07858799
Phase 3Taking people
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
Where
Bad Oldesloe, Bamberg, Berlin, Bielefeld, Bremen, Chemnitz, Cologne, Dresden, Elsterwerda, Erlangen, Essen, Freiburg im Breisgau, Gera, Hamburg, Heidelberg, Homburg, Jena, Kaiserslautern, Karlsbad, Kiel, Ludwigshafen, Ludwigshafen Am Rhein, Lüneburg, Magdeburg, Mainz, Markkleeberg, Mühldorf am Inn, Neuruppin, Nürnberg, Obertshausen, Paderborn, Papenburg, Stuttgart, Trier, Tuebingen, Ulm
Age
18 years and over
People
6,950 worldwide
Run by
AstraZeneca
See details and how to joinNCT07761117 · EU 2026-526304-79-00
Phase 2Taking people
Impact of Glucagon on Physical Capacity and Metabolism
Where
Bochum
Age
18 years and over
People
33
Run by
Katholisches Klinikum Bochum gGmbH
See details and how to join2025-521835-35-00 · EU 2025-521835-35-00
No phaseTaking people
Left Bundle Branch Area Pacing (LBBAP) PMCF Study
Where
Bad Nauheim
Age
18 years and over
People
200 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT07217392
No phaseNot yet taking people in Germany
A Comparison of Left Bundle Branch Optimized Cardiac Resynchronization Therapy vs Left Bundle Branch Area Pacing Alone
Where
Neuruppin
Age
18 years and over
People
124
Run by
PD Dr. Guram Imnadze
See details and how to joinNCT07842874
No phaseTaking people
Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)
Where
Berlin
Age
18 years and over
People
149 worldwide
Run by
Echosens
See details and how to joinNCT07222813
No phaseTaking people
AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure
Where
Munich
Age
18 years to 99 years
People
40
Run by
Technical University of Munich
See details and how to joinNCT06650995
No phaseTaking people
Tezspire Cardiac Events PASS
Where
Berlin
Age
12 years to 130 years
People
16,640 worldwide
Run by
AstraZeneca
See details and how to joinNCT06951867
Phase 1/2Taking people
A Phase 1b/2a Trial to Evaluate Invobenitug Also Known as Procizumab (PCZ; AK1967) in Critical Cardiovascular Care.
Where
Bad Krozingen, Berlin, Hamburg, Leipzig, Mannheim
Age
18 years to 80 years
People
90 worldwide
Run by
4TEEN4 Pharmaceuticals GmbH
See details and how to joinNCT06832722 · EU 2024-518450-16-00
Phase 2Not yet taking people in Germany
A Study to Evaluate the Safety and Efficacy of AC01 Compared to Placebo in Participants With Chronic Heart Failure
Where
Freiburg im Breisgau, Jena, Magdeburg, Neuwied, Papenburg
Age
18 years to 85 years
People
400 worldwide
Run by
AnaCardio AB
See details and how to joinNCT07584967 · EU 2025-524469-25-00
No phaseTaking people
BAROSTIM THERAPY™ in Heart Failure With Reduced Ejection Fraction
Where
Bad Oeynhausen, Berlin, Bernau, Chemnitz, Cologne, Detmold, Dresden, Frankfurt, Giessen, Göttingen, Hamburg, Hamm, Hanover, Ingolstadt, Kiel, Lahr, Leipzig, Mainz, Münster, Paderborn, Regensburg, Siegen, Stadtlohn, Tuttlingen
People
500 worldwide
Run by
CVRx, Inc.
See details and how to joinNCT02880618
No phaseTaking people
Pacing Advancements With Cost and Experience VALuation for Unified Patient-Led Clinical Evidence - the PACEVALUE Study
Where
Bad Krozingen
Age
18 years and over
People
4,500 worldwide
Run by
Insel Gruppe AG, University Hospital Bern
See details and how to joinNCT07276139
Phase 3Taking people
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Where
Berlin, Dresden, Giessen, Jena, Lübeck, Regensburg
Age
18 years and over
People
5,200 worldwide
Run by
Colorado Prevention Center
See details and how to joinNCT06008197
No phaseTaking people
Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
Where
Berlin, Essen, Frankfurt am Main, Würzburg
Age
18 years and over
People
500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07690436
Phase 1Taking people
A STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF COR-1389
Where
Neuss
Age
18 years to 64 years
People
140
Run by
Corteria Pharmaceuticals
See details and how to join2024-514853-31-00 · EU 2024-514853-31-00
No phaseTaking people
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
Where
Aalen, Berlin, Bernau, Dresden, Erlangen, Leipzig, Münster
Age
18 years and over
People
1,700 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT05489705
Phase 3Taking people
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Where
Aachen, Bad Friedrichshall, Bad Oeynhausen, Berlin, Bochum, Coburg, Cologne, Dresden, Elsterwerda, Erfurt, Essen, Frankfurt Am Main, Freiburg im Breisgau, Hamburg, Kaiserslautern, Kamp-Lintfort, Kiel, Langen (Hesse), Ludwigshafen am Rhein, Mainz, Markkleeberg, Muenster, Neuruppin, Osnabrueck, Papenburg, Rostock, Rotenburg A. D. Fulda, Stuhr, Stuttgart, Traunstein, Wermsdorf, Weyhe-Leeste, Witten, Wuerzburg
Age
18 years and over
People
5,610 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07567001 · EU 2025-523717-29-00
No phaseTaking people
Alleviant ALLAY-HF Study
Where
Hamburg, Lübeck, Magdeburg
Age
40 years and over
People
700 worldwide
Run by
Alleviant Medical, Inc.
See details and how to joinNCT05685303
No phaseTaking people
Multimodal Phenotyping In Patients Referred With Acute Cardiac faiLurE
Where
Bad Krozingen, Freiburg im Breisgau, Nuremberg, Villingen-Schwenningen
Age
18 years and over
People
600
Run by
University Heart Center Freiburg - Bad Krozingen
See details and how to joinNCT07515508
No phaseTaking people
Early Detection and IntervenTion in Heart Failure
Where
Freiburg im Breisgau, Herne, Leipzig
Age
65 years and over
People
18,000 worldwide
Run by
University Hospital, Basel, Switzerland
See details and how to joinNCT07731490
Phase 3Taking people
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Where
Frankfurt am Main
Age
2 years to 11 years
People
9 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597006